DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment BtbVII and CG6765

DIOPT Version :9

Sequence 1:	NP_647774.2	Gene:	BtbVII / 38376	FlyBaseID:	FBgn0263108	Length:	907	Species:	Drosophila melanogaster
Sequence 2:	NP_001261582.1	Gene:	CG6765 / 38971	FlyBaseID:	FBgn0035903	Length:	681	Species:	Drosophila melanogaster

Alignment Length:	831	Identity:	163/831 - (19%)
Similarity:	261/831 - (31%)	Gaps:	312/831 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSVQQFCLRWNNHQPNFISVCSSLLHNGTLVDVTLAAEGRQ-----------LQAHKIVLSACSS 54
            |:.:.:.|:|::|.....|..::|..|....||.|.:....           :.|||.:|||.|.
  Fly     1 MAAENYHLKWDSHLTYLNSSIATLYKNEKFADVVLYSSYNSSGIPSDIPTVGISAHKFILSASSQ 65

  Fly    55 YFQALFTTNPCQHP-----IVILKDVQYDDLKTMVDFMYYGEVNVSQEQLPHILKTAEMLKIKGL 114
            :|..:|.|.|..:|     :|:..|:.:..::.:|.:||.||..||.:.|..:|:..|:|||:||
  Fly    66 FFATMFETAPITNPNGVLYVVLPPDLSHRAIQILVQYMYSGEATVSNDILNEVLRGGEILKIRGL 130

  Fly   115 AEMPTDPANLTKSDSKSSTDGTEMVGGAGVGTGAGNSAGSLGAGSGSSVGDSLWSSSEAQQFQQQ 179
            .                                  .::.|.|.||||.|..:
  Fly   131 C----------------------------------RTSSSNGGGSGSVVTTT------------- 148

  Fly   180 QQQQAQQQAQQQHHHHQQQQQLQQQQQQAQ-----------------QQQQQQQHHHHHHQQQQS 227
                        ||.|.....|..::....                 |.....|.....:..:..
  Fly   149 ------------HHPHSLAGHLHPREASTMYMSNGTRTALPPPPPPPQSTMSAQLQGDLYASKPG 201

  Fly   228 GQAQAAQTHHHQMRRTPSPLSAGTSPATRRKRLRKSSNNGSGDRNNAEEQHNSSLDAGSGAGNAG 292
            |..:.|..|||                       .||::...:.:|.::|..     |.||
  Fly   202 GSTRFALDHHH-----------------------LSSHHSHLNHHNPQQQFR-----GLGA---- 234

  Fly   293 LSLAQMNQMTFGAGGGLAGHSLHAAKLLKESASAELEQQPQDSDLDDGHGHLHMQIKPEVDIG-G 356
             |:...:.........||.|:    .||..::|::|                          | .
  Fly   235 -SVMPKDSPVIIKSPKLAAHT----GLLTVASSSKL--------------------------GIS 268

  Fly   357 VNQTMPLDISGGTTPSE---HDAPNSQSSHSEPSPAHAPHPPHPPLGAASSSSGGSGSFERSFSI 418
            ||:.:.:|      |.:   ..||....|.|        ||| ||....::..||.|      |:
  Fly   269 VNKEVAID------PEDKCCFAAPGQLESQS--------HPP-PPTTTTTTVGGGGG------SV 312

  Fly   419 GGVGSVE------CDPDGTPSSPAVMGTKRNRVLTRQPRVKRDSDSISSTNQISPDTAATTLDFD 477
            ||.|:..      |...|..|.|...|...::..|...|.:.:..::...|::.       |.|:
  Fly   313 GGSGAPPSQPISICTEVGCSSCPLTAGPGADQAETTLRRTEYEEQALRERNEVG-------LVFE 370

  Fly   478 PFNAAGATSATARDYSTTGSHHLH--------------------HQSAVHHHHHLLTV------- 515
            ......:....:||| ....|..|                    |...:.|.|:.||:
  Fly   371 RRLRRESACERSRDY-YEAPHFEHVVSSRLAATPPPPPQQAPPSHPPTLRHPHNFLTIKQEPTDW 434

  Fly   516 ---PPRIERHAS----EPAPSLAPSTP-------------------------HLLSVPSS----- 543
               ||.....::    |..|..:|..|                         |.|...::
  Fly   435 SNNPPNASSASNNNNLEELPLASPKQPLDFKMSAVKLEVNRDRGTPSEESEEHTLRDYNNFKQLL 499

  Fly   544 -----------TPYLIKQ---HS-DP-------LLPRQSALHMAGSGSGSSSAMATGS-NPFAPL 585
                       |..|::.   |: ||       |||..:    :||.:.:||.:|..| ..:.|.
  Fly   500 VCEICQKSFEDTKMLVRHLGTHAGDPTGGTERNLLPSSA----SGSTTSASSNLALRSVKTYVPK 560

  Fly   586 HRQYSHPLSGS-------------NASYVTPAP-LHH--PHHISLPESIYASGS----------P 624
            .|:.......:             :.|:.|||. :.|  ..|..:..:::.|..          |
  Fly   561 KRRRVSQQENNMDHDHVTLLCDLCSTSFDTPAEWVRHMNSQHTEIELAMFNSKKDGEQKGQQPPP 625

  Fly   625 PPAGSSQYLVPTRVVACPVVSSETAATPTNASPGSSSTVSAAVSVVTSPNA 675
            |||.||...|....:. |...|.||...|::......:.|.||:..|||.|
  Fly   626 PPATSSSSTVSNSQMQ-PKYPSSTATRSTHSLMLHKMSNSDAVATTTSPGA 675

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
BtbVII	NP_647774.2	BTB	24..117	CDD:279045	34/108 (31%)
BtbVII	NP_647774.2	BTB	32..117	CDD:197585	32/100 (32%)
CG6765	NP_001261582.1	BTB	24..132	CDD:279045	34/141 (24%)
CG6765	NP_001261582.1	BTB	53..130	CDD:197585	27/76 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000141
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23110
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	3.010