Protein Alignment BtbVII and Zbtb37

DIOPT Version :10

• Sequence 1: NP_647774.2
• Gene: BtbVII / 38376
• FlyBaseID: FBgn0263108
• Length: 907
• Species: Drosophila melanogaster
• Sequence 2: NP_775600.1
• Gene: Zbtb37 / 240869
• MGIID: 2444467
• Length: 504
• Species: Mus musculus
• Alignment Length: 696
• Identity: 118/696 - (16%)
• Similarity: 214/696 - (30%)
• Gaps: 257/696 - (36%)

  Fly    15 PNF----ISVCSSLLHNGTLVDVTLAAEGRQLQAHKIVLSACSSYFQALFTTNPCQH-PIVILKD 74
            |:|    :|..:.|...|.|.|:.:..:|:..:|||:||:|.|.||:...:.|.... .|.::|:
Mouse    14 PDFSNSVLSHLNQLRMQGRLCDIVVNVQGQAFRAHKVVLAASSPYFRDHMSLNEMSTVSISVIKN 78

  Fly    75 VQYDDLKTMVDFMYYGEVNVSQEQLPHILKTAEMLKIKGLAEMPTDPANLTKSDSKSSTDGTEMV 139
            ...  .:.::.|.|.|.:.:....:...|..|..|:::.:.:..|
Mouse    79 PTV--FEQLLSFCYTGRICLQLADIISYLTAASFLQMQHIIDKCT-------------------- 121

  Fly   140 GGAGVGTGAGNSAGSLGAGSGSSVGDSLWSSSEAQQFQQQQQQQAQQQAQQQHHHHQQQQQLQQQ 204
                                                           |..:..|......:::.:
Mouse   122 -----------------------------------------------QILEGIHFKINVAEVEAE 139

  Fly   205 QQQAQQQQQQQQHHHHHHQQQQSGQAQAAQTHHHQMRRTPSPLSAGTSPATRRKRLRKSSNNGSG 269
            ..|.:.:.|::....|                    |.||: |:...||
Mouse   140 LSQTRTKHQERPPESH--------------------RATPN-LNRSLSP---------------- 167

  Fly   270 DRNNAEEQHNSSLDAGSGAGNAGLSLAQMNQMTFGAGGGLAGHSLHAAKLLKESASAELEQQPQD 334
                   :||:|.....|..:|.|.:.:::..                   :|..|.::.:|..|
Mouse   168 -------RHNASKGNWRGQVSAVLDIRELSPP-------------------EEPTSPQIIEQSSD 206

  Fly   335 SD---------------LDDGHGHLHMQIKPEVDI-GGVN-QTMPLDISGGTTPSEHDAPNSQSS 382
            ::               ::.|......:...||.: |.|: :|..|:        |...|.:|.|
Mouse   207 AEGREPILRINRAGQWYVETGLADQGARSGDEVRVLGAVHIKTENLE--------EWLGPENQPS 263

  Fly   383 HSEPSPAHAPHPPHPPLGAASSSSGGSGSF-ERSFSIGGVGSVECDPDG------TPSSPAVMGT 440
            ..:.|.|.       .:.|....:.|.||. :.|:::|..|:....|..      :||...|..|
Mouse   264 GEDGSSAE-------EVTAMVIDTTGHGSIGQESYTLGSSGAKVARPTSSEVDRFSPSGSVVSMT 321

  Fly   441 KRNRVLTRQPRVKRDSDSISSTNQISPDTAATTL-----------DFDPFNAAGATSATARDYST 494
            :|:|..:..|....:...:||..:.|.....:..           .:..:|........|:.::.
Mouse   322 ERHRARSESPGRMDEPKQLSSQVEESAMMGVSAYVEYLREQEVSERWFRYNPRLTCIYCAKSFNQ 386

  Fly   495 TGSHHLHHQSAVHHHHHLLTVPPRIERHASEPAPSLAPSTPHLLSVPSSTPYLIKQHSDPLLPRQ 559
            .||  |.....:|     :.:.|.:.|...:.           .:......|.|::|:.   .:.
Mouse   387 KGS--LDRHMRLH-----MGITPFVCRMCGKK-----------YTRKDQLEYHIRKHTG---NKP 430

  Fly   560 SALHMAGSGSGSSSAMATGSNPFAPL---HRQYSHPLSGSNASYVTPAPLHHPHHISLPESIYAS 621
            ...|:.|.           |.||..:   |.:.:||  |.       .||..||.|| ||:...|
Mouse   431 FHCHVCGK-----------SFPFQAILNQHFRKNHP--GC-------IPLEGPHSIS-PETTVTS 474

  Fly   622 -----GSPPPAGSSQYLVPTRVVACPVVSSETAATPTNASPGSSST 662
                 |||                    |.|....|..::.||.||
Mouse   475 RQAEEGSP--------------------SHEEIVAPGESAQGSVST 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
BtbVII	NP_647774.2	BTB_POZ_BAB-like	30..113	CDD:349624	21/83 (25%)
Zbtb37	NP_775600.1	BTB_POZ_ZBTB37	9..131	CDD:349531	29/185 (16%)
		C2H2 Zn finger	377..397	CDD:275368	4/21 (19%)
		zf-H2C2_2	389..414	CDD:463886	5/42 (12%)
		zf-C2H2	403..425	CDD:395048	3/32 (9%)
		C2H2 Zn finger	405..425	CDD:275368	3/30 (10%)
		zf-H2C2_2	418..440	CDD:463886	5/35 (14%)
		C2H2 Zn finger	433..451	CDD:275368	6/28 (21%)