Protein Alignment BtbVII and ttk

DIOPT Version :10

• Sequence 1: NP_647774.2
• Gene: BtbVII / 38376
• FlyBaseID: FBgn0263108
• Length: 907
• Species: Drosophila melanogaster
• Sequence 2: XP_061497449.1
• Gene: ttk / 1274194
• VectorBaseID: AGAMI1_010022
• Length: 885
• Species: Anopheles gambiae
• Alignment Length: 1011
• Identity: 245/1011 - (24%)
• Similarity: 378/1011 - (37%)
• Gaps: 310/1011 - (30%)

  Fly     1 MSVQQFCLRWNNHQPNFISVCSSLLHNGTLVDVTLAAEGRQLQAHKIVLSACSSYFQALFTTNPC 65
            |:.|:|||||||||.|.::|...|||:.|.:|||||.||:.|:|||:||||||.|||.||.::|.
Mosquito     1 MTSQRFCLRWNNHQTNLLAVFDQLLHDETFIDVTLAVEGQHLKAHKMVLSACSPYFQQLFVSHPE 65

  Fly    66 QHPIVILKDVQYDDLKTMVDFMYYGEVNVSQEQLPHILKTAEMLKIKGLAEMPTDPANLTKSDSK 130
            :||||||:||.:.|:|.::||||.|||:|.|::|...|:.||.|:||||.|:..|..| ..|.|.
Mosquito    66 KHPIVILRDVPFKDMKCLLDFMYRGEVSVDQDRLAAFLRVAESLRIKGLTEVNDDKPN-APSGSA 129

  Fly   131 SSTDGTEMVGGAGVGTGAGNSAGSLGAGSGSSVGDSLWSSSEAQQFQQQQQQQAQQQAQQQHHHH 195
            |:|              |.|||||..:....:.|.:..:::......|:....:.....|.....
Mosquito   130 SAT--------------ATNSAGSAASSGAQATGATTTTNTVPNATVQKNSSGSSGMVSQVDDDE 180

  Fly   196 QQQ-----QQLQQQQQQAQQQQQQQQH----------------HHHHHQQQQSGQAQAAQTHHHQ 239
            ..:     ..:......|...|.|..|                .|.:...||.|.:.|:.:   .
Mosquito   181 DDRCSPVPNSIAVAPNAASSGQAQGGHLKPLPPLLSSTGIVTRSHSNSLLQQGGSSAASGS---A 242

  Fly   240 MRRTPSPLSAGTSPATRRK-RLRKSSNNGSGDRNN-----------AEEQHNSSLD------AGS 286
            |.:|...|....|...|:: |.||.|.:.:|:...           .||..:||:|      |.|
Mosquito   243 MVQTNPLLGTALSQQKRKRGRPRKLSGSDAGEGETEGNFVGGGGAPGEEYDSSSMDIMDVKIASS 307

  Fly   287 GAGNAGLSLAQMNQMTFGAGGGLAGHSLHAAKLLKESASA-----------ELEQQPQDSDLDDG 340
            ||.|:|....|:..        ::..:.....|:.|.|..           |.::...|.||:.|
Mosquito   308 GASNSGDDDQQLRI--------VSSRTDDDDTLMHEKAEQLDDEDDEVMDDEADELVDDVDLEAG 364

  Fly   341 HGHLHMQIKPEVDIGGVNQTMPLDISG---GTTPSEHDAPNSQSSHSEPSPAHAPHPPHPPLGAA 402
            .       :|......::::|. |.:|   |||.:..:...|...|.:...|.|     .|..|:
Mosquito   365 D-------EPRGTSPSLDESME-DTTGNMDGTTNNNGNTNRSGRQHQKQGTAAA-----KPSRAS 416

  Fly   403 ---------SSSSGGSGSF---ERSFSIGGVGS------VECDP-DGTPSSPAVMGTKRNRVLTR 448
                     :|.|....||   ::...:.|.|:      :|.|. ||...:.::|
Mosquito   417 KRSRTRNNENSLSDSKDSFAEDDKCNKLDGTGAGEEEDDIEDDQYDGRELNSSLM---------- 471

  Fly   449 QPRVKRDSDSISSTNQISPDTAATTLDFDPFNAAGATSATARDYSTTGSHHLHHQSAVHHHHHLL 513
            :|::..|...           ......|||...:||..      ||:.|::|
Mosquito   472 EPQLLLDEYD-----------EPVEFKFDPRTDSGAVD------STSNSNYL------------- 506

  Fly   514 TVPPRIERHASEPAPSLAPST-------PHLLSVPSSTPYLIKQHSDPLLPRQSALHMAGSGSGS 571
              ||      .:|.|.|..::       |.:..||::...:.|     |.|      :..||.|:
Mosquito   507 --PP------LQPKPGLKIASTSGGARMPQISVVPTTALQIPK-----LAP------LTASGGGT 552

  Fly   572 SSAMATGSNPFAPLHRQYSHPLSGSNASYVTPAPLHHPHHISLPESIYASGSPPPAGSSQYLVPT 636
            ||.:..|||                |.|.|   .||....:..|:.        |.|    :..|
Mosquito   553 SSFLGGGSN----------------NKSSV---KLHKRARLMTPKK--------PNG----MTTT 586

  Fly   637 RVVACPV---VSSETAATPTNASPGSSSTVSAAVSVVTSPNAG--LQNSASRHPLSPTFSIGSDV 696
            :.:...:   ::....:|...||.|||..::...|.:....:|  |::|      ||
Mosquito   587 QTILNNLNNNLNESLISTSNTASGGSSLCITGIGSEMYDMFSGSVLRSS------SP-------- 637

  Fly   697 AHERRSPHSPSISRSQVVERAGKNPAEAANGGGSRLRTSKSASGSITGTHLHPGQATMSSSFEHL 761
               |.:.:|||:                           |..||:.:|:..|.....
Mosquito   638 ---RSNSNSPSV---------------------------KGGSGNDSGSRTHKYAVI-------- 664

  Fly   762 PTLRVKNEELQRSVSSPQTQREIITLENPRSSHCPVIRPGPALGCNFCWNTIDGHGRILRRKTK- 825
                   ::.:.||      |:..|.|......|.|.........|||.:.:..|    :|..|
Mosquito   665 -------DDTEGSV------RDFCTKEGDHVYRCKVCARVYTHISNFCRHYVTSH----KRNVKV 712

  Fly   826 YHCPEC------QTNLCI---VPCFQEYHERLN-----NEAAAASSGAAAGDNQLSSSTT---GS 873
            |.||.|      :.|:..   :...|||.::..     ...:.||.|.:....:.|.|.|   |.
Mosquito   713 YPCPFCLKEFTRKDNMTAHVKIIHKQEYAQQQTTGVGPGGTSPASGGGSNSRGEESFSATLVGGR 777

  Fly   874 GSSSSGKASPYVSS----------AGSSSSGAGAAR 899
            ..|::|.:|...:|          .|::|.|.||.|
Mosquito   778 NDSTNGGSSLTTASIINAVGLQPKLGTNSGGTGAIR 813

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
BtbVII	NP_647774.2	BTB_POZ_BAB-like	30..113	CDD:349624	48/82 (59%)
ttk	XP_061497449.1	None