Protein Alignment BtbVII and Btbd18

DIOPT Version :10

• Sequence 1: NP_647774.2
• Gene: BtbVII / 38376
• FlyBaseID: FBgn0263108
• Length: 907
• Species: Drosophila melanogaster
• Sequence 2: NP_001138572.1
• Gene: Btbd18 / 100270744
• MGIID: 3650217
• Length: 723
• Species: Mus musculus
• Alignment Length: 761
• Identity: 160/761 - (21%)
• Similarity: 254/761 - (33%)
• Gaps: 188/761 - (24%)

  Fly    15 PNFISVCSSLLH----NGTLVDVTLAAEGRQLQAHKIVLSACSSYF-QALFTTNPCQHPIVILK- 73
            |.|:.|....||    :|...|..|.|||..:.||..:|||||.:| :.|....|.|...|:|:
Mouse    14 PRFLRVAFLQLHHQQQSGVFCDALLQAEGEAVPAHCCILSACSPFFTERLERERPVQGRKVVLEM 78

  Fly    74 -DVQYDDLKTMVDFMYYGEVNVSQEQLPHILKTAEMLKIKGLAEMPTDPANLTKSDS-------- 129
             .::...|:.:|||:|..|:.||||:...:|..|..|::..|..:..:...|.|:..
Mouse    79 GGLKIQTLRKLVDFLYTSEMEVSQEEAQDVLSAARQLRVSELETLQLEGGKLVKAPQGRRLNREC 143

  Fly   130 ----KSSTDGTEMVGGAG---VGTGAGNSAGSLGAGSGSSVGDSLWSSSEAQQFQQQQQQQAQQQ 187
                .::.....:||...   .......:...|||....|:|               :::.|.::
Mouse   144 LQPPAAAPISARVVGPKSRPQTPLPVTQTPSPLGAVRLKSLG---------------EEEGAHKK 193

  Fly   188 AQQQHHHHQQQQQLQQQQQ----QAQQQQQQQQHHHHHHQQQQSG-------------------- 228
            ....:.......||:::.:    |..:.....|.......:...|
Mouse   194 TNLPNADSLSDTQLKKKARVCLTQESRSSPSSQREGPKETKSNPGPTALPSLYPSVDEQLLPRKI 258

  Fly   229 QAQAAQTHHHQMRRTPS-----PLSAGTSPATRRKRLRKSSNNGSG-DRNN-AEEQHNSSLDAGS 286
            :...::...|....|||     |.|..|:|..|..|.|..|....| |:.. .|.:...|....|
Mouse   259 RLSRSKPSPHVYTSTPSSILSGPSSMPTAPGRRLWRQRTVSKEAQGVDKQKPGEVRPLQSTPDPS 323

  Fly   287 GAGNAGLSLAQMNQMTFGAGGGLAGHSLHAAKLLK--ESASAELEQQP-----QD-------SDL 337
            ..|....:..|..::.......:....:...||.|  .....|:.|:|     ||       ||:
Mouse   324 DVGKPAENKKQSPELRAPTSSSVEEGQVGRVKLRKIVNGTCWEVVQEPPLRNTQDSPQILEPSDV 388

  Fly   338 DDGHGHLHMQIKPEVDIGGVN-QTMPLDISGGTTPSEHDAPNS--------QSSHSEPSPAHAPH 393
            ::..|.|         :..|| |.:|..|.     ...|:|.|        .:|||
Mouse   389 EEPSGTL---------LSSVNEQEIPARIQ-----LCQDSPESPRLQDILLSASHS--------- 430

  Fly   394 PPHPPLGAASSSSGGSGSFERSFSIGGVGSVECDPDGTPSSPAVMGTKRNRVLTRQP------RV 452
            |.||.:.:...||......|...:|      :|      ..|....|    .|..||      |:
Mouse   431 PDHPMVKSEFGSSPMLTGKESDLNI------DC------REPYTFDT----TLLGQPCEAEQYRI 479

  Fly   453 KRDSDSISSTNQISP--DTAATTLDFDPFNAAGATSATARDYSTTGSHHLHHQSAVHHHHHLLTV 515
                .|.::|:::..  |......|.:|  ..|:..:...:...|.|:||..............:
Mouse   480 ----TSAAATSELEEIFDFMLCGSDVEP--PVGSLESPGAEGCRTPSYHLSETGKNWIEGEEWCL 538

  Fly   516 P-----PR----IERH-ASEPAPSLAPSTPHLLSVPSSTPYLIKQHSDPLLP-----RQSALHMA 565
            |     ||    :|:. .||....:.|.:|.::...::..:      :||.|     ..|...::
Mouse   539 PDMELWPRDLTGLEKEPVSENKEPVEPFSPLVMRSENTESF------EPLSPLVMPSEVSREELS 597

  Fly   566 GSGSGSSSAMATGSNPF-----APLHRQYSHPLSGSNASYVTPAPLHHPHHISLPESIYA-SGSP 624
            ..||.:.....|.|.|.     ..||...|.|   |..||         :|:|.|.|.:| :|..
Mouse   598 LRGSWTPDLEITSSQPLDGQGEKLLHFDSSDP---SQRSY---------NHLSPPCSDWAETGLE 650

  Fly   625 PPAGSSQYLVPTRVVACPVVSSETAATPTNASPGSSSTVSAAVSVV 670
            ...|....|.|.     |....|.:|.|....|...|:....:.||
Mouse   651 VSLGMDDVLCPV-----PKAVREVSANPEQLDPLPGSSEDEEIDVV 691

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
BtbVII	NP_647774.2	BTB_POZ_BAB-like	30..113	CDD:349624	31/85 (36%)
Btbd18	NP_001138572.1	BTB_POZ_BTBD18	20..138	CDD:349602	37/117 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	150..176		2/25 (8%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	188..350		25/161 (16%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	370..394		5/23 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	603..637		10/45 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	699..723