Protein Alignment Usp5 and Usp27x

DIOPT Version :10

• Sequence 1: NP_647773.1
• Gene: Usp5 / 38375
• FlyBaseID: FBgn0035402
• Length: 827
• Species: Drosophila melanogaster
• Sequence 2: NP_062334.2
• Gene: Usp27x / 54651
• MGIID: 1859645
• Length: 438
• Species: Mus musculus
• Alignment Length: 588
• Identity: 117/588 - (19%)
• Similarity: 194/588 - (32%)
• Gaps: 219/588 - (37%)

  Fly   285 FGINMAAMKKSE-----KSMVELELDINQR------IGE----WTALTESESEL-------QPVA 327
            :.|::..:.|.|     |.......:::|:      :||    |.. |:.|.||       :.:|
Mouse     7 YDIDIEQIAKEEQGEALKLQASTSTEVSQQQCSVPGLGEKYPTWET-TKPELELLGHNPRRRRIA 70

  Fly   328 GP---GYTGMRNLGNSCYINSVMQVLFVIPDFQQRFVGTGAERYFKEFPSDPANDFNIQMAKLGT 389
            ..   |..|:.||||:|::|.::|.|...|..:..|:   ::|:..|.|| |......:|:.|..
Mouse    71 SSFTIGLRGLINLGNTCFMNCIVQALTHTPILRDFFL---SDRHRCEMPS-PELCLVCEMSSLFR 131

  Fly   390 GLQSGKYSSIAENTLDTDHSTGISPAMFKNIVGKNHPDFSTKQQQDANDFYLHLLTLLDRNSRNQ 454
            .|.||..|...             |....::|..:....:..:||||::|.:..|.:|.|:.:..
Mouse   132 ELYSGNPSPHV-------------PYKLLHLVWIHARHLAGYRQQDAHEFLIAALDVLHRHCKGD 183

  Fly   455 ------TNPADALKFL-------LEDRVECLASHKVKYNTREEYSFRLPVPLDKATNLDEVREFQ 506
                  :||......:       |:..|.|.|.|.|                  :|.:|
Mouse   184 DVGKVASNPNHCNCIIDQIFTGGLQSDVTCQACHGV------------------STTID------ 224

  Fly   507 ERKKAARETGQRLPDRDIVRHKVPLQACLERFFGPELIEQFYSTAIGSKTNAR---KITRLATMP 568
                         |..||   .:.|         |.....|:..:.|.:::..   .|..:.|:.
Mouse   225 -------------PCWDI---SLDL---------PGSCTSFWPMSPGRESSLNGESHIPGITTLT 264

  Fly   569 DCLMIHVGKFTLGDDWVPKKLDVSVDMPDELDLSNWRSAGGLQPGEEALPEPATEEVKFAFDEAV 633
            |||.    :||               .|:.|..|.....|..|..:|:
Mouse   265 DCLR----RFT---------------RPEHLGSSAKIKCGSCQSYQES----------------- 293

  Fly   634 MSELLTMGFPPEACKRACYHTKNSGLEAASNWLMEHIADEDISEPFVVPNNSIGDCAANQFVANP 698
             ::.|||...|..   ||:|.|.          .||.|.:         ...|     ..:::.|
Mouse   294 -TKQLTMKKLPVV---ACFHFKR----------FEHSAKQ---------RRKI-----TTYISFP 330

  Fly   699 ESLAMLMSMGFDERQAVAALKATDGNVERATDWIFSHADSIGVEDAAPAANSSAAAASSTPNKTN 763
            ..|.|...|...:...|      :|.::.                                 .||
Mouse   331 LELDMTPFMASSKETRV------NGQLQL---------------------------------PTN 356

  Fly   764 YRDGRGKYRLVAFISHMGTSAQVGHYVCHIR-KKGEWVIFNDSKVAKSQNPPKDL----GYLYLY 823
            ..:...||.|.|.::|.|| .:.|||...|| .:.:|...:|:.:.|:.  .||:    |||..|
Mouse   357 SANNENKYSLFAVVNHQGT-LESGHYTSFIRHHRDQWFKCDDAVITKAS--IKDVLDSEGYLLFY 418

  Fly   824 MRE 826
            .::
Mouse   419 HKQ 421

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp5	NP_647773.1	zf-UBP_var	11..77	CDD:407678
		zf-UBP	204..278	CDD:460464
		Peptidase_C19B	333..823	CDD:239123	102/510 (20%)
		UBA1_UBP5_like	631..674	CDD:270480	11/42 (26%)
		UBA2_UBP5	696..737	CDD:270569	6/40 (15%)
Usp27x	NP_062334.2	Peptidase_C19D	78..419	CDD:239125	102/512 (20%)