Protein Alignment Usp5 and Usp12-46

DIOPT Version :10

• Sequence 1: NP_647773.1
• Gene: Usp5 / 38375
• FlyBaseID: FBgn0035402
• Length: 827
• Species: Drosophila melanogaster
• Sequence 2: NP_651099.1
• Gene: Usp12-46 / 42702
• FlyBaseID: FBgn0039025
• Length: 424
• Species: Drosophila melanogaster
• Alignment Length: 619
• Identity: 96/619 - (15%)
• Similarity: 153/619 - (24%)
• Gaps: 324/619 - (52%)

  Fly   318 ESESELQPVAGPGYTGMRNLGNSCYINSVMQVLFVIPDFQQRFVGTGAERYFKEFPSDPANDFNI 382
            |..|:|.| ....|.|:.|.||:||.|||:|.|:....|:::.:      .:|.....|......
  Fly    11 EIGSDLFP-PNEHYFGLVNFGNTCYSNSVLQALYFCKPFREKVL------EYKAKNKRPKETLLS 68

  Fly   383 QMAKL--GTGLQSGKYSSIAENTLDTDHSTGISPAMFKNIVGKNHPDFSTKQQQDANDF------ 439
            .:|.|  ....|..|..|||             |..|...:.|...:|....||||::|
  Fly    69 CLADLFYSIATQKKKVGSIA-------------PKKFITRLRKEKEEFDNYMQQDAHEFLNFLIN 120

  Fly   440 YLHLLTLLDR-----------------------------------------------NSRNQTNP 457
            :::.:.|.:|                                               ||.|.|..
  Fly   121 HINEIILAERNAGPSNGNPKATNQGGSTSAMASSIASKSSSTSNSNSNSNSTTNSNGNSSNSTGS 185

  Fly   458 ADA---------------------------------------LKFLLEDRVECLASHKVKYNTRE 483
            .:|                                       .:.:|.....||....|  ::::
  Fly   186 LNANTSVLDASGSLTATTTPIISGNGTGTNGANSEPTWVHEIFQGILTSETRCLNCETV--SSKD 248

  Fly   484 EYSFRLPVPLDKATNLDEVREFQERKKAARETGQRLPDRDIVRHKVPLQACLERFFGPELI---E 545
            |..|.|.|.:|:.|::..                                ||..|...|.:   .
  Fly   249 ENFFDLQVDVDQNTSITH--------------------------------CLRCFSNTETLCSDN 281

  Fly   546 QFYSTAIGSKTNARKITRLATMPDCLMIHVGKFTLGDDWVPKKLDVS--VDMPDELDLSNWRSAG 608
            :|......|...|:|..|:..:|..|.:|:.:|...:.: .:.:.||  |..|.||.|.|
  Fly   282 KFKCDNCCSYQEAQKRMRVKKLPMILALHLKRFKYMEQF-NRHIKVSHRVVFPLELRLFN----- 340

  Fly   609 GLQPGEEALPEPATEEVKFAFDEAVMSELLTMGFPPEACKRACYHTKNSGLEAASNWLMEHIADE 673
                               ..|:||
  Fly   341 -------------------TSDDAV---------------------------------------- 346

  Fly   674 DISEPFVVPNNSIGDCAANQFVANPESLAMLMSMGFDERQAVAALKATDGNVERATDWIFSHADS 738
                                   ||:.|
  Fly   347 -----------------------NPDRL------------------------------------- 351

  Fly   739 IGVEDAAPAANSSAAAASSTPNKTNYRDGRGKYRLVAFISHMGTSAQVGHYVCHIRKKGEWVIFN 803
                                            |.|.|.:.|.|:....|||:..::..|.|::|:
  Fly   352 --------------------------------YDLTAVVIHCGSGPNRGHYISIVKSHGLWLLFD 384

  Fly   804 DSKVAKSQ--------------NPPKDLGYLYLY 823
            |..|.|.:              :...:.||:..|
  Fly   385 DDMVDKIEASTIEDFYGLTSDIHKSSETGYILFY 418

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp5	NP_647773.1	zf-UBP_var	11..77	CDD:407678
		zf-UBP	204..278	CDD:460464
		Peptidase_C19B	333..823	CDD:239123	90/602 (15%)
		UBA1_UBP5_like	631..674	CDD:270480	2/42 (5%)
		UBA2_UBP5	696..737	CDD:270569	3/40 (8%)
Usp12-46	NP_651099.1	Peptidase_C19G	25..419	CDD:239128	91/604 (15%)