Protein Alignment Usp5 and Usp29

DIOPT Version :10

• Sequence 1: NP_647773.1
• Gene: Usp5 / 38375
• FlyBaseID: FBgn0035402
• Length: 827
• Species: Drosophila melanogaster
• Sequence 2: NP_001101935.1
• Gene: Usp29 / 361495
• RGDID: 1306648
• Length: 872
• Species: Rattus norvegicus
• Alignment Length: 618
• Identity: 122/618 - (19%)
• Similarity: 216/618 - (34%)
• Gaps: 204/618 - (33%)

  Fly   333 GMRNLGNSCYINSVMQVLFVIPDFQQRFVGTGAERYFKEFPSDPA--NDFNIQMAKL-------- 387
            |..||||:||:||::|.:|.||.|.:..:..|       .|.:..  :|..:.:::|
  Rat   294 GFPNLGNTCYMNSILQSVFGIPTFAKDLLTQG-------IPWEKVSYDDLIMPLSQLLVLKDIRD 351

  Fly   388 ----GTGLQSGKYSSIAENTLDTDHSTGISPAMFKNIVGKNHPDFSTKQQQDANDFYLHLLTLL- 447
                |..|.|.|.|  .....||                     ||..:|.||::|....|..|
  Rat   352 IEIKGELLTSVKKS--ISTVADT---------------------FSGNEQNDAHEFLSLCLDQLK 393

  Fly   448 ----------DRNSRNQTNPADALKFL----------LEDRVECLASHKVKYNTREEYSFRLPVP 492
                      |...:|:...|.|.:|:          |...:.|....:....|  |.|..|.:.
  Rat   394 LNMEKVNAMWDTERKNEPTCAGAKRFVCPVGANFEFELHSSIICEGCGEATLKT--EVSNYLSID 456

  Fly   493 LDKATNLDEVREFQERKKAARETGQRLPDRDIVRHKVPLQACLERFFGPELIEQFYSTAIGSKTN 557
            |...|.                           .|.:.:|...:.||.||.||. ......:|.:
  Rat   457 LHHGTK---------------------------THPLSIQKSFDLFFTPEKIEH-NCEKCKNKNS 493

  Fly   558 ARKITRLATMPDCLMIHVGKFTLGDDWVPKKLDVSVDMPDELDLS--------------NWRSAG 608
            ..|.| |..:|..|::|:.::.:..|.:|.|.:..|::...|::|              |....|
  Rat   494 VLKYT-LRRLPRVLIVHLKRYQVTTDLLPVKSEQPVEISQYLNISSHCHENRKLPFPLINTPPKG 557

  Fly   609 -----GLQPGEEALPEPATEEVKFAFDEAVMSE-----LLTMGFPPEA---CKRACYHTKNS--- 657
                 .:.||  .:||..::.:.   .:.|:||     :|.:|...:|   ..:..|..::.
  Rat   558 DYDIPNVSPG--LMPEIFSQSMS---SKKVISESSDPLVLQVGSSVDAEIQSFQIMYEDESEEEQ 617

  Fly   658 --GLEAASNWLMEHIADED------------------------ISEPFVVPNNSIGDCAANQFVA 696
              |||:.|....|.:..|:                        :.||..:.:..:.:....:...
  Rat   618 QRGLESGSMLDPELLKTENRVFRQKISPAPDSMMGDGYSFLPMLCEPMSIQDPGLAEMGLQEVPE 682

  Fly   697 NPE-------------SLAML------------MSMGFDERQAVAALKATDGNVERATDWIFSHA 736
            |||             .|:.|            :...|...:  ::|:..:.::.|::::
  Rat   683 NPEFKYYGKPDGRTNSELSKLHQNHGGRIKGSYLPASFANMR--SSLEDPEKDLSRSSEF----- 740

  Fly   737 DSIGVEDAAPAANSSAAAASSTPNKTNYRDGRGKYRLVAFISHMGTSAQVGHYVCHIR--KKGEW 799
                 |:..|   .|.|..|.........|....||||:.:||.|:|...||||..:.  ::..|
  Rat   741 -----EEDDP---HSFALGSDESKDEEMGDNLHNYRLVSVVSHFGSSPNSGHYVSDVYDFQRQAW 797

  Fly   800 VIFNDSKVAKSQNPPKD-----LGYLYLYMREQ 827
            ::::|.:|.::.:|...     .||::.||..:
  Rat   798 LLYSDVQVFENPDPSSQENRLHTGYIFFYMHNE 830

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp5	NP_647773.1	zf-UBP_var	11..77	CDD:407678
		zf-UBP	204..278	CDD:460464
		Peptidase_C19B	333..823	CDD:239123	120/612 (20%)
		UBA1_UBP5_like	631..674	CDD:270480	12/55 (22%)
		UBA2_UBP5	696..737	CDD:270569	8/65 (12%)
Usp29	NP_001101935.1	PH_USP37_like	4..109	CDD:270122
		UCH	294..560	CDD:425685	69/326 (21%)
		Peptidase_C19	<765..826	CDD:470612	18/60 (30%)