Protein Alignment Usp5 and Usp7

DIOPT Version :10

• Sequence 1: NP_647773.1
• Gene: Usp5 / 38375
• FlyBaseID: FBgn0035402
• Length: 827
• Species: Drosophila melanogaster
• Sequence 2: NP_572779.2
• Gene: Usp7 / 32169
• FlyBaseID: FBgn0030366
• Length: 1129
• Species: Drosophila melanogaster
• Alignment Length: 729
• Identity: 128/729 - (17%)
• Similarity: 235/729 - (32%)
• Gaps: 277/729 - (37%)

  Fly   113 SDMAKKYEIKDT------YSIVVAPHLD-----KKLPYPDPELPMRVTQSVEAILAADSAIAKLE 166
            ||:.:..:.:::      :..::.|.|.     .:||..:..:|.:.       |.|||:.....
  Fly    25 SDLQQTQQQRNSPPQLPKFKNLIQPQLHAVGAVTQLPSENGNMPPQQ-------LLADSSSTSFG 82

  Fly   167 KATLMGTWD----GEVRQASKYA---DNLQQLDNGKRIPPSGWQCEKCDLTNNLWLNLTDGSIMC 224
            ....||..|    .:.|..:.::   :|:.||.:.:..||             :::.:....||
  Fly    83 DGEAMGIDDESKEDQFRSETTFSFTVENVVQLKSQRLSPP-------------VYVRMLPWRIM- 133

  Fly   225 GRKFFDGSGGNDHAVEHYRVTGFPLAVKLGTITADGKSDVFSYPED---EMVLDPHLE------- 279
                         .:.:.|..||       .:..:|::|..::..:   |:.|..|..
  Fly   134 -------------VIPNDRALGF-------FLQCNGENDSPTWSCNAIAELRLKCHKPDAQPFTR 178

  Fly   280 ---RHL----------SHFGINMAAMKKSEKSMVE-----LELDINQRIGE------WTALTESE 320
               :||          |:| |....:|.||||.|.     ||:.:   :.:      |.:...:
  Fly   179 ARIKHLFYSKENDYGYSNF-ITWQELKDSEKSYVHNNSITLEVHV---VADAPHGVLWDSKKHT- 238

  Fly   321 SELQPVAGPGYTGMRNLGNSCYINSVMQVLFV----------IP---DFQQRFVGTGAERYFKE- 371
                     ||.|::|.|.:||:||::|.|:.          ||   |...:.||...:|.|.|
  Fly   239 ---------GYVGLKNQGATCYMNSLLQTLYFTNSLRLSVYRIPTEADDSSKSVGLSLQRVFHEL 294

  Fly   372 -FPSDPANDFNIQMAKLGTGLQSGKYSSIAENTLDTDHSTGISPAMFKNIVGKNHPDFSTKQQQD 435
             |...|          :||...:   .|....|||                        :..|.|
  Fly   295 QFGDRP----------VGTKKLT---KSFGWETLD------------------------SFMQHD 322

  Fly   436 ANDFYLHLLTLLDRNSRNQTNPADALKFLLEDRVECLASHK-VKYN-TREEYSFRLPVPLDKATN 498
            ..:|...||..|:...:. |.....:..|.|.::......| |.|| ||.|..:.:.:.:....|
  Fly   323 VQEFLRVLLDKLESKMKG-TILEGTIPGLFEGKMSSYIKCKNVDYNSTRYETFYDIQLNIKDKKN 386

  Fly   499 LDEVREFQERKKAARETGQRLPDRDIVRHKVPLQACLERFFGPELIE--QFYSTAIGSKTNARKI 561
            :.|  .||:                              :..||.:|  ..|...:.....|.|.
  Fly   387 IYE--SFQD------------------------------YVAPETLEGDNKYDAGVHGLQEASKG 419

  Fly   562 TRLATMPDCLMIHVGKF---TLGDDWVPKKLDVSVDMPDELDLSNWRSAGGLQPGEEALPE---- 619
            ....:.|..|.:|:.:|   .:.|..:  |.:...:..:.::|..:     |...|..|.:
  Fly   420 VIFTSFPPVLHLHLMRFQYDPVTDSSI--KYNDRFEFYEHINLDRY-----LAESENTLADYVLH 477

  Fly   620 -------------------PATEEVKFAFDEAVMSELLTMGFPPEACKR--------------AC 651
                               |..:...|.||:.|:|          :|::              ..
  Fly   478 AVLVHSGDNHGGHYVVFINPKADGRWFKFDDDVVS----------SCRKQEAIEQNYGGMDDEIS 532

  Fly   652 YHTKNSGL-------EAASNWLMEHIADEDISEPFV-----------VPNNSIGDCAANQFVANP 698
            :|.|.|..       ::..:.::..|.:.:||...|           ......|:  ||.:|
  Fly   533 FHAKCSNAYMLVYIRQSELDRVLGDITESEISSDLVERLDLEKRIEMARRKERGE--ANTYV--- 592

  Fly   699 ESLAMLMSMGFDER 712
             |:.:::...|:|:
  Fly   593 -SVHVILEENFEEQ 605

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp5	NP_647773.1	zf-UBP_var	11..77	CDD:407678
		zf-UBP	204..278	CDD:460464	9/76 (12%)
		Peptidase_C19B	333..823	CDD:239123	82/457 (18%)
		UBA1_UBP5_like	631..674	CDD:270480	7/63 (11%)
		UBA2_UBP5	696..737	CDD:270569	3/17 (18%)
Usp7	NP_572779.2	Peptidase_C19	101..1119	CDD:470612	113/646 (17%)