Protein Alignment Usp5 and C04E6.5

DIOPT Version :10

• Sequence 1: NP_647773.1
• Gene: Usp5 / 38375
• FlyBaseID: FBgn0035402
• Length: 827
• Species: Drosophila melanogaster
• Sequence 2: NP_504537.1
• Gene: C04E6.5 / 178977
• WormBaseID: WBGene00015422
• Length: 515
• Species: Caenorhabditis elegans
• Alignment Length: 639
• Identity: 126/639 - (19%)
• Similarity: 194/639 - (30%)
• Gaps: 270/639 - (42%)

  Fly   261 KSDVFSYPEDEMVLDPHLERHLSHFGINMAAMKKSEKSMVE----------LELDI------NQR 309
            :|:||          |....|.|....|..:.|::...:.|          :..|:      |.|
 Worm    74 RSEVF----------PEQLEHPSKNATNTGSRKRAHPKLFEASEPKVKSSNVSTDVIDGKKHNNR 128

  Fly   310 IGEWTALTESESELQPVAGPGYTGMRNLGNSCYINSVMQVLFVIPDFQQRFVGTGAERYF----- 369
                  .|.|......|.......:.|.||||::||.||.|.....|..|     .|:.:
 Worm   129 ------KTNSSRSFSKVNSSVTRKLVNTGNSCFLNSTMQALSSCHSFALR-----CEQLYCLVRK 182

  Fly   370 --KEFPSDPAN------------DFNIQMAKLGTGLQSGK-YSSIAENTLDTDHSTGISPAMFKN 419
              ..|.::.::            ||...||.|.....|.| ...|.|..|.|          |:.
 Worm   183 NIDYFDNEASHSEVLCRKYRVLIDFLKIMAALTKRSNSSKTQPEIIEANLQT----------FRE 237

  Fly   420 IVGKNHPDFSTKQQQDANDFYLHLLTLLDR-------------NSRNQTNPADALKFLLEDRVEC 471
            ::|....||:.|.||||::|.|.|...:|.             ....|.||.:|.||.:|....|
 Worm   238 LIGMIRNDFANKNQQDAHEFLLMLFEAIDDVAEYKADNEGDDVKEAKQLNPIEAFKFNVETCYVC 302

  Fly   472 LASHKVKYNTREEYSFRLPVPLDKATNLDEVREFQERKKAARETGQRLPDRDIVRHKVPLQACLE 536
                  |..::||  .|:.|..|.|.::                          |..:.:|
 Worm   303 ------KGCSKEE--VRVDVRNDLAVHM--------------------------RDNLSVQ---- 329

  Fly   537 RFFGPELIEQFYS--TAIGSKTN---------ARKITRLATMPDCLMIHVGKFTL-GDDWVPKKL 589
                 ||:...:|  |.|..|.:         :.:|||   .|:||:|::.::.| |..:..||:
 Worm   330 -----ELLSSSFSTWTPIEKKCSSCNHQHAILSERITR---FPECLVINLERYQLEGPQFSTKKI 386

  Fly   590 DVSVDMPDELDLSNWR-----SAGGLQPGEEALPEPATEEVKFAFDEAVMSELLTMGFPPEACKR 649
            :.|::...|||:|:.:     ...||:..|:.             .::...:||......|..|
 Worm   387 NCSLEPSFELDISSLQKFPEIEKNGLEQSEKQ-------------QDSQYGQLLDRMKSCEIIK- 437

  Fly   650 ACYHTKNSGLEAASNWLMEHIADEDISEPFVVPNNSIGDCAANQFVANPESLAMLMSMGFDERQA 714
             |..|||.        :||...|
 Worm   438 -CCETKNI--------IMEEKHD------------------------------------------ 451

  Fly   715 VAALKATDGNVERATDWIFSHADSIGVEDAAPAANSSAAAASSTPNKTNYRDGRGKYRLVAFISH 779
                                                                   ||.|||.|.|
 Worm   452 -------------------------------------------------------KYSLVAAICH 461

  Fly   780 MGTSAQVGHYVCHIRKKGE--WVIFNDSKVAKSQNPPKDL-----GYLYLYMRE 826
            :|.:...|||:.:.|:..|  |:..:|..:..:......|     ||:..|..|
 Worm   462 LGETPTNGHYIAYTREDTENSWLYCSDDLIRPATRSEISLSIRTSGYILFYEYE 515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp5	NP_647773.1	zf-UBP_var	11..77	CDD:407678
		zf-UBP	204..278	CDD:460464	4/16 (25%)
		Peptidase_C19B	333..823	CDD:239123	109/546 (20%)
		UBA1_UBP5_like	631..674	CDD:270480	11/42 (26%)
		UBA2_UBP5	696..737	CDD:270569	0/40 (0%)
C04E6.5	NP_504537.1	Peptidase_C19Q	146..513	CDD:239138	109/547 (20%)