Protein Alignment Usp5 and Usp5

DIOPT Version :10

• Sequence 1: NP_647773.1
• Gene: Usp5 / 38375
• FlyBaseID: FBgn0035402
• Length: 827
• Species: Drosophila melanogaster
• Sequence 2: XP_320294.4
• Gene: Usp5 / 1280441
• VectorBaseID: AGAMI1_007862
• Length: 833
• Species: Anopheles gambiae
• Alignment Length: 841
• Identity: 506/841 - (60%)
• Similarity: 635/841 - (75%)
• Gaps: 25/841 - (2%)

  Fly     1 MEELRKHLSKVNVPCASGAGSPPIYKDECVYSYDNPETPTGLYVCLHSFLGFGEAYVREYADKTG 65
            |:.|||:|::|.||||    |..:||:|||||:|||||.|||||.|.|||||||.|||.||:::|
Mosquito     1 MDTLRKYLAQVKVPCA----SDNVYKEECVYSFDNPETDTGLYVSLASFLGFGEQYVRPYAERSG 61

  Fly    66 NRVFLHIQRVKTIKEGADMEAECAESEAGPERKITRLAIGVEGGYNESDMAKKYEIKDTYSIVVA 130
            ||||||::|.| |:......|:.|....|||:|||||||||||||..:: :||||.::.|.:||.
Mosquito    62 NRVFLHLKRDK-IEIPDPSAADGAGGADGPEKKITRLAIGVEGGYTGAE-SKKYEYQEHYQVVVF 124

  Fly   131 PHLDKKLPYPDPELPMRVTQSVEAILAADSAIAKLEKATLMGTWDGEVRQASKYADNLQQLDNGK 195
            .....:|.||:.:||::|..::||:..|::|..|.|:..:.||||||:||.|.:|..|.||||||
Mosquito   125 DEPVVRLDYPNVDLPLQVQNAIEAVQKAEAASVKREREQMAGTWDGEIRQVSTHAAELLQLDNGK 189

  Fly   196 RIPPSGWQCEKCDLTNNLWLNLTDGSIMCGRKFFDGSGGNDHAVEHYRVTGFPLAVKLGTITADG 260
            :|||:||:|||||||:||||||||||||||||||||||||||||.||:.|.:|||||||||||||
Mosquito   190 KIPPTGWKCEKCDLTSNLWLNLTDGSIMCGRKFFDGSGGNDHAVNHYKETNYPLAVKLGTITADG 254

  Fly   261 KSDVFSYPEDEMVLDPHLERHLSHFGINMAAMKKSEKSMVELELDINQRIGEWTALTESESELQP 325
            |.||:||.||:||.||:|.:||:|:|||:..::|:||||:|||||:|||||||..|.||.|:|:|
Mosquito   255 KGDVYSYSEDDMVEDPYLVKHLAHWGINVGQLEKTEKSMIELELDLNQRIGEWGILCESGSQLKP 319

  Fly   326 VAGPGYTGMRNLGNSCYINSVMQVLFVIPDFQQRFVGTGAERYFKEFPSDPANDFNIQMAKLGTG 390
            :||||||||:||||:||:||||||||.||||.:||| .|::..|..||||||||||:||||||||
Mosquito   320 IAGPGYTGMKNLGNTCYLNSVMQVLFTIPDFVRRFV-DGSKAIFDSFPSDPANDFNVQMAKLGTG 383

  Fly   391 LQSGKYSSIAENTLDTDHST--GISPAMFKNIVGKNHPDFSTKQQQDANDFYLHLLTLLDRNSRN 453
            |.||:||.::|::|||..||  ||:|.|||.::|:.||||||||||||.:|:||:::.|:::||:
Mosquito   384 LCSGRYSVLSESSLDTADSTTGGIAPTMFKALIGQGHPDFSTKQQQDAQEFFLHIISTLEKHSRH 448

  Fly   454 QTNPADALKFLLEDRVECLASHKVKYNTREEYSFRLPVPLDKATNLDEVREFQERKKAARETGQR 518
            |.||::||:|.:||||||.:|.||.||.|:|:...|.:||.||||||||::::..:.||...|:|
Mosquito   449 QANPSEALRFCIEDRVECCSSGKVMYNRRDEWCLPLQIPLQKATNLDEVKQYEAERAAAEREGRR 513

  Fly   519 LPDRDIVRHKVPLQACLERFFGPELIEQFYSTAIGSKTNARKITRLATMPDCLMIHVGKFTLGDD 583
            |....:||.|:.|.|||:.|..|||:|||||||||:||.|:|.|:||:|||.|::|:.||||.:|
Mosquito   514 LDPDALVRPKITLAACLDTFAQPELVEQFYSTAIGAKTTAKKTTKLASMPDYLLLHLKKFTLKED 578

  Fly   584 WVPKKLDVSVDMPDELDLSNWRSAGGLQPGEEALPEPA-TEEVKFAFDEAVMSELLTMGFPPEAC 647
            |...||||::|:|:.|||...|.. |.||.||.||:.| .|......|..||.:||.||||||||
Mosquito   579 WTSLKLDVAIDIPEVLDLETLRGT-GKQPYEEELPDIAGREPTPPPMDPEVMEQLLGMGFPPEAC 642

  Fly   648 KRACYHTKNSGLEAASNWLMEHIADEDISEPFVVP--NNSIGDCAANQFVANPESLAMLMSMGFD 710
            |||.:.|||:|:|.|:.|:||||||.|.:.|||.|  .......|...||.||..|.|||.|||.
Mosquito   643 KRAIFFTKNTGIEPATQWMMEHIADADFASPFVPPGTGGKSSSAAGAAFVPNPVGLEMLMGMGFS 707

  Fly   711 ERQAVAALKATDGNVERATDWIFSHA---DSIGVED--------AAPAANSSAAAASSTPNKTNY 764
            :|||..|||.|..|.|||.||||||.   ||:.::|        ||.||.|...||.|... ::|
Mosquito   708 DRQATKALKETGNNTERAVDWIFSHTDELDSMAIDDATSDSVATAAAAAGSDGGAAGSKQG-SSY 771

  Fly   765 RDGRGKYRLVAFISHMGTSAQVGHYVCHIRKKGEWVIFNDSKVAKSQNPPKDLGYLYLYMR 825
            |||.|||:|||||||||||||||||||||.|.|:||||||:|||.||||||:|||||||.|
Mosquito   772 RDGTGKYKLVAFISHMGTSAQVGHYVCHILKDGQWVIFNDNKVAISQNPPKELGYLYLYQR 832

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp5	NP_647773.1	zf-UBP_var	11..77	CDD:407678	44/65 (68%)
		zf-UBP	204..278	CDD:460464	62/73 (85%)
		Peptidase_C19B	333..823	CDD:239123	295/505 (58%)
		UBA1_UBP5_like	631..674	CDD:270480	28/42 (67%)
		UBA2_UBP5	696..737	CDD:270569	26/43 (60%)
Usp5	XP_320294.4	None