Protein Alignment Usp5 and USP17L15

DIOPT Version :10

• Sequence 1: NP_647773.1
• Gene: Usp5 / 38375
• FlyBaseID: FBgn0035402
• Length: 827
• Species: Drosophila melanogaster
• Sequence 2: NP_001243823.2
• Gene: USP17L15 / 100288520
• HGNCID: 44443
• Length: 553
• Species: Homo sapiens
• Alignment Length: 301
• Identity: 54/301 - (17%)
• Similarity: 100/301 - (33%)
• Gaps: 100/301 - (33%)

  Fly   333 GMRNLGNSCYINSVMQVLFVIPDFQQRFVGTGAERYFKEFPSDPANDFNIQMAKLGTGLQSGKYS 397
            |::|:||:||:|:.:|.|...|                               .|...:.|.::|
Human    81 GLQNMGNTCYVNASLQCLTYTP-------------------------------PLANYMLSREHS 114

  Fly   398 SIAENTLDTDHSTGISPAMFKNIVGKNH-------------PDFSTKQQQDANDFYLHLLTLL-- 447
            .....     |...:...|..:|....|             ..|...:|:||::|.:..:..:
Human   115 QTCHR-----HKGCMLCTMQAHITRALHNPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKK 174

  Fly   448 ---------DRNSRNQTNPADALKFLLEDRVECLASHKVKYNTREEYSFRLPVPLDKATNLDEVR 503
                     |.:|::.|............:::||..|.:. :|.:.|       ||.|.::...:
Human   175 ACLPGHKQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGIS-DTFDPY-------LDIALDIQAAQ 231

  Fly   504 EFQERKKAARETGQRLPDRDIVRHKVPLQACLERFFGPELI--EQFYSTAIG-SKTNARKITRLA 565
            ..|:                          .||:...||.:  |..|...:. .:..|.|...|.
Human   232 SVQQ--------------------------ALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLH 270

  Fly   566 TMPDCLMIHVGKFTLGDDWVPKKLDVSVDMPDELDLSNWRS 606
            |....|::.:.:|:   |....|:|.:|..|:.||:..:.|
Human   271 TSAKVLILVLKRFS---DVTGNKIDKNVQYPECLDMKLYMS 308

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp5	NP_647773.1	zf-UBP_var	11..77	CDD:407678
		zf-UBP	204..278	CDD:460464
		Peptidase_C19B	333..823	CDD:239123	54/301 (18%)
		UBA1_UBP5_like	631..674	CDD:270480
		UBA2_UBP5	696..737	CDD:270569
USP17L15	NP_001243823.2	Peptidase_C19E	79..373	CDD:239126	54/301 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	382..413
		HABP4_PAI-RBP1	<417..454	CDD:461421
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	491..524