DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Alg2 and AT1G78800

DIOPT Version :9

Sequence 1:	NP_647772.1	Gene:	Alg2 / 38374	FlyBaseID:	FBgn0035401	Length:	424	Species:	Drosophila melanogaster
Sequence 2:	NP_178001.2	Gene:	AT1G78800 / 844216	AraportID:	AT1G78800	Length:	403	Species:	Arabidopsis thaliana

Alignment Length:	434	Identity:	181/434 - (41%)
Similarity:	253/434 - (58%)	Gaps:	58/434 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 VRVLFLHPDLGIGGAERLVVDAALALKERGHQVSFLTNHHDSTHCFKETADGTFPVHVVGDWLPR 66
            :.:..:||||||||||||:||||:.|...||:|...|:|||.:.||:||..|.|.|.|.|.:|||
plant     9 MNIAIIHPDLGIGGAERLIVDAAVELASHGHKVHIFTSHHDKSRCFEETLSGIFQVTVYGSFLPR 73

  Fly    67 GLFGRFYAICAYLRMLYAAI-----YASFFMPQREQVDVVVCDLISVCIPVLRFAPHRPKVLFYC 126
            .:|.|.:|:|||||.|:.|:     ::||        |||:.|.:||.:|:|:. ....||:|||
plant    74 HIFYRLHAVCAYLRCLFVALCVLLGWSSF--------DVVLADQVSVVVPLLKL-KRSSKVVFYC 129

  Fly   127 HFPDQLLSSREGLLKRLYRLPINWLEEHTIGLADKVLVNSKFTLRVFQDTFRRLS---TVPDVLY 188
            ||||.||:.....|:|:||.||:::||.|.|:||.:||||.||...|.:||:||:   :.|.|||
plant   130 HFPDLLLAKHTTTLRRMYRKPIDFIEEQTTGMADMILVNSNFTASTFANTFKRLNAQGSRPAVLY 194

  Fly   189 PSLHTQYFDQMQKKLEQRSALLDEPVHPRV-PLNAFIYLDINRYERKKNHALALHSLRLLGDMLP 252
            |:::                 :|:.:.|.. .||   :|.|||:|||||..||:.:..:|
plant   195 PAVN-----------------IDQFIEPHTYKLN---FLSINRFERKKNIDLAVSAFAIL----- 234

  Fly   253 ATDFKRCR---------LIIAGGYDTRCMENVEHFAELEHLTEELKLQDHVVLLRSPTDEEKCRL 308
                  |:         |.:|||||.|..||||:..||..|.|:..:.|.|..:.|.:..|:..|
plant   235 ------CKHKQNLSDVTLTVAGGYDERLKENVEYLEELRSLAEKEGVSDRVNFITSCSTAERNEL 293

  Fly   309 LFAAHCLLYTPENEHFGIVPLEGMYCSKPVVALNSGGPTETVVSTSTGFLCEKTEKSFGGAMLQL 373
            |.:..|:||||.:|||||||||.|...|||:|.|||||.|||.:..||:|||.|.:.|..||.:.
plant   294 LSSCLCVLYTPTDEHFGIVPLEAMAAYKPVIACNSGGPVETVKNGVTGYLCEPTPEDFSSAMARF 358

  Fly   374 FRDEQLRVKMGDQGHKRVQQKFSFQAFADRLNGIIRDLVPISRE 417
            ..:.:|..:||.:....|.:.||.:.|..:||..:.|:|...:|
plant   359 IENPELANRMGAEARNHVVESFSVKTFGQKLNQYLVDVVSSPKE 402

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Alg2	NP_647772.1	RfaB	1..412	CDD:223515	179/427 (42%)
Alg2	NP_647772.1	GT1_ALG2_like	2..404	CDD:99977	176/419 (42%)
AT1G78800	NP_178001.2	RfaB	8..398	CDD:223515	179/428 (42%)
AT1G78800	NP_178001.2	GT1_ALG2_like	9..389	CDD:99977	176/419 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	164	1.000	Domainoid score	I1222
eggNOG	1	0.900	-	-		E1_COG0438
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5930
Inparanoid	1	1.050	320	1.000	Inparanoid score	I707
OMA	1	1.010	-	-		QHG53746
OrthoDB	1	1.010	-	-		D1339573at2759
OrthoFinder	1	1.000	-	-		FOG0005034
OrthoInspector	1	1.000	-	-		oto4185
orthoMCL	1	0.900	-	-		OOG6_102563
Panther	1	1.100	-	-	LDO	PTHR45918
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3559
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.840