DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG11537 and QDR1

DIOPT Version :9

Sequence 1:NP_001097489.1 Gene:CG11537 / 38373 FlyBaseID:FBgn0035400 Length:705 Species:Drosophila melanogaster
Sequence 2:NP_012146.1 Gene:QDR1 / 854686 SGDID:S000001382 Length:563 Species:Saccharomyces cerevisiae


Alignment Length:483 Identity:88/483 - (18%)
Similarity:173/483 - (35%) Gaps:108/483 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly   257 LVVI---FLEFFAW--GLLTMPIISTLNQTFPDHTFLMNGLVMGIKGILSFLSAPLIGALSDIWG 316
            |:|:   |..||:.  |.:..|:::.:.:.|.....|.|..:: :..|...::..::|.|:|.:|
Yeast    70 LLVVQCAFTGFFSTVAGSIYYPVLTIIERKFNITEELANVTIV-VYFIFQGVAPSIMGGLADTFG 133

  Fly   317 RKFFLLVTVF-FTCLPIPLMSINTWWFFAMI---------SISGAFAVTFSVVFAYVADVTTPEE 371
            |:..:|..:. :.|..|.|...:.   :|.|         .||...|:...:    :.||||..|
Yeast   134 RRPIVLWAILAYFCACIGLACAHN---YAQILALRCLQAAGISPVIAINSGI----MGDVTTKVE 191

  Fly   372 RSKAYGLASATFAASLVISPALGNALMEMYGDTLV---VALSTAIALLDVFFILVAVPESL---- 429
            |....||.:............:|..|...:|...:   :|:.:.|.|:   |..:.:||:.    
Yeast   192 RGGYVGLVAGFQVVGTAFGALIGAGLSSKWGWRAIFWFLAIGSGICLV---FSTLLMPETKRTLV 253

  Fly   430 -SEKMRPASW---------GA---PISWEQADP----------FLALRKVGTDKTVLMLCLTVLL 471
             :..:.|.|:         |:   .:..:..||          |||..|:...:.:.:|.....|
Yeast   254 GNGSVTPRSFLNRSLILHVGSVKKTLHLDDPDPETLEPRTSVDFLAPLKILHIREIDILLSIAGL 318

  Fly   472 SYLPEAGEYSCMFVYLKLKMGFNYVEVSVFIAIVGILSITVQVTLGSFMQVFGAKRTI------- 529
            .:.......:.:.:.|..|...:..::.:.....||.::|..::.|.::......|.:       
Yeast   319 QFSTWTTHQTALTIVLSKKYNLSVAKIGLCFLPAGISTLTSIISAGRYLNWSYRTRKVKYNRWIK 383

  Fly   530 ---------IMGLALEIVQLL----WYGFGSQKWMMWSAGVVAALGSITYPAISAFVSLYAAPES 581
                     ..|...::.:|:    .|.|...:..:..|.|...|.||.:.|....:|       
Yeast   384 EQELQLMEKYKGDKNKVAELIHSNSHYAFNLVEARLHPAFVTLLLSSIGFTAFGWCIS------- 441

  Fly   582 QGAVQGMITGMRGLCNGLGPAVFGVVFYLFNVDLNDDHDSHAKSSGSRATNVEKISQHVPGPPFV 646
               |:..:..:  ||.....::|......|:..|..|......|:.:...|:.:           
Yeast   442 ---VKTPLAAV--LCTSAFASLFSNCILTFSTTLIVDLFPSKASTATGCLNLFR----------- 490

  Fly   647 FGALCVFCAIIVSAFIPEGQTSTLEKKR 674
                |:..||.::|.     |..:||.|
Yeast   491 ----CLLSAIFIAAL-----TKMVEKMR 509

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG11537NP_001097489.1 MFS 256..612 CDD:119392 75/419 (18%)
MFS_1 257..601 CDD:284993 74/408 (18%)
QDR1NP_012146.1 MFS_Tpo1_MDR_like 72..516 CDD:340881 87/481 (18%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C157341877
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.930

Return to query results.
Submit another query.