Protein Alignment CG11537 and QDR1

DIOPT Version :10

• Sequence 1: NP_001097489.1
• Gene: CG11537 / 38373
• FlyBaseID: FBgn0035400
• Length: 705
• Species: Drosophila melanogaster
• Sequence 2: NP_012146.1
• Gene: QDR1 / 854686
• SGDID: S000001382
• Length: 563
• Species: Saccharomyces cerevisiae
• Alignment Length: 483
• Identity: 88/483 - (18%)
• Similarity: 173/483 - (35%)
• Gaps: 108/483 - (22%)

  Fly   257 LVVI---FLEFFAW--GLLTMPIISTLNQTFPDHTFLMNGLVMGIKGILSFLSAPLIGALSDIWG 316
            |:|:   |..||:.  |.:..|:::.:.:.|.....|.|..:: :..|...::..::|.|:|.:|
Yeast    70 LLVVQCAFTGFFSTVAGSIYYPVLTIIERKFNITEELANVTIV-VYFIFQGVAPSIMGGLADTFG 133

  Fly   317 RKFFLLVTVF-FTCLPIPLMSINTWWFFAMI---------SISGAFAVTFSVVFAYVADVTTPEE 371
            |:..:|..:. :.|..|.|...:.   :|.|         .||...|:...:    :.||||..|
Yeast   134 RRPIVLWAILAYFCACIGLACAHN---YAQILALRCLQAAGISPVIAINSGI----MGDVTTKVE 191

  Fly   372 RSKAYGLASATFAASLVISPALGNALMEMYGDTLV---VALSTAIALLDVFFILVAVPESL---- 429
            |....||.:............:|..|...:|...:   :|:.:.|.|:   |..:.:||:.
Yeast   192 RGGYVGLVAGFQVVGTAFGALIGAGLSSKWGWRAIFWFLAIGSGICLV---FSTLLMPETKRTLV 253

  Fly   430 -SEKMRPASW---------GA---PISWEQADP----------FLALRKVGTDKTVLMLCLTVLL 471
             :..:.|.|:         |:   .:..:..||          |||..|:...:.:.:|.....|
Yeast   254 GNGSVTPRSFLNRSLILHVGSVKKTLHLDDPDPETLEPRTSVDFLAPLKILHIREIDILLSIAGL 318

  Fly   472 SYLPEAGEYSCMFVYLKLKMGFNYVEVSVFIAIVGILSITVQVTLGSFMQVFGAKRTI------- 529
            .:.......:.:.:.|..|...:..::.:.....||.::|..::.|.::......|.:
Yeast   319 QFSTWTTHQTALTIVLSKKYNLSVAKIGLCFLPAGISTLTSIISAGRYLNWSYRTRKVKYNRWIK 383

  Fly   530 ---------IMGLALEIVQLL----WYGFGSQKWMMWSAGVVAALGSITYPAISAFVSLYAAPES 581
                     ..|...::.:|:    .|.|...:..:..|.|...|.||.:.|....:|
Yeast   384 EQELQLMEKYKGDKNKVAELIHSNSHYAFNLVEARLHPAFVTLLLSSIGFTAFGWCIS------- 441

  Fly   582 QGAVQGMITGMRGLCNGLGPAVFGVVFYLFNVDLNDDHDSHAKSSGSRATNVEKISQHVPGPPFV 646
               |:..:..:  ||.....::|......|:..|..|......|:.:...|:.:
Yeast   442 ---VKTPLAAV--LCTSAFASLFSNCILTFSTTLIVDLFPSKASTATGCLNLFR----------- 490

  Fly   647 FGALCVFCAIIVSAFIPEGQTSTLEKKR 674
                |:..||.::|.     |..:||.|
Yeast   491 ----CLLSAIFIAAL-----TKMVEKMR 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11537	NP_001097489.1	MFS_MFSD14	253..663	CDD:340945	84/470 (18%)
QDR1	NP_012146.1	MFS_Tpo1_MDR_like	72..516	CDD:340881	87/481 (18%)