DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11537 and MEE15

DIOPT Version :9

Sequence 1:	NP_001097489.1	Gene:	CG11537 / 38373	FlyBaseID:	FBgn0035400	Length:	705	Species:	Drosophila melanogaster
Sequence 2:	NP_001323497.1	Gene:	MEE15 / 816200	AraportID:	AT2G16970	Length:	460	Species:	Arabidopsis thaliana

Alignment Length:	488	Identity:	106/488 - (21%)
Similarity:	185/488 - (37%)	Gaps:	130/488 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   248 IGEPSVHHALVVIFLEFFAWGLLTMPII---------STLNQTFPDHTFLMNGLVMGIKGILSFL 303
            :||  :.|.|..:||..|: ..|..|::         |.||:|.....:| .|:.....|:.:.:
plant     6 LGE--LRHLLTTVFLSGFS-EFLVKPVMTDVTVAAVCSGLNETCSLAVYL-TGVEQVTVGLGTMV 66

  Fly   304 SAPLIGALSDIWGRKFFLLVTVFFTCLPIPLMSI--NTWWFFAMISISGAFAVT---FSVV---- 359
            ..|:||.|||.:|.|..|.:.:..:.||..:::.  :|.:|:       ||.:|   |.:|
plant    67 MMPVIGNLSDRYGIKTLLTLPMCLSILPPAILAYRRDTNFFY-------AFYITKILFDMVCQGT 124

  Fly   360 -----FAYVADVTTPEERSKAYGLAS---------ATFAASLVISPALGNALMEMYGDTLVVALS 410
                 .||||......:|...:|:.:         |||:|.|                 |.:|..
plant   125 VDCLAHAYVAKNVCGRKRISMFGVLAGVRSISGVCATFSARL-----------------LPIASI 172

  Fly   411 TAIALLDVFFILVAVPESLSEKM-----------------------------RPASWGAP----- 441
            ..:|.:..||.||.:...|.|::                             .|....||
plant   173 FQVAAISFFFGLVYMRVFLKERLHDDDEDDCDEDDNTSGRNHHDGGDLTMLAEPILRDAPTKIHI 237

  Fly   442 ---ISWEQADPFLALRKVGTDKTVLMLCLTV-LLSYLPEAGEYSCMFVYLKLKMGFN---YVEVS 499
               ..:......::|.|   :.|:|:..|.| ..:...::|..|....:||.:.|||   :.|:.
plant   238 VLNTKYSSLKDMVSLIK---NSTILVQTLVVTFFATFAQSGMQSAFLYFLKARFGFNKNDFAELI 299

  Fly   500 VFIAIVGILSITVQVTLGSFMQVFGAKRTIIMGLALEIVQLLWYGFGSQKWMMWSAGVVAALGSI 564
            :.:.|:|  ||:....|...:...|.:|.:..||.::.|...........|:.::..|:..:...
plant   300 LLVTIIG--SISQLFILPKLVSAIGERRVLSTGLLMDSVNAACLSVSWSAWVPYATTVLVPVTMF 362

  Fly   565 TYPAISAFVSLYAAPESQGAVQGMITGMRGLCNGLGPAVFGVVFYLFNVDLNDDHDSHAKSSGSR 629
            ..|::....|....|..||.|||.|:|::.....:.|.::..:..||   |:
plant   363 VMPSVCGIASRQVGPGEQGKVQGCISGVKSFSGVVAPFIYSPLTALF---LS------------- 411

  Fly   630 ATNVEKISQHVPGPPFVFGALCVFCAIIVSAFI 662
                ||...:.||    |..|||..::::..|:
plant   412 ----EKAPFYFPG----FSLLCVTFSLMIGFFL 436

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11537	NP_001097489.1	MFS	256..612	CDD:119392	92/428 (21%)
CG11537	NP_001097489.1	MFS_1	257..601	CDD:284993	90/416 (22%)
MEE15	NP_001323497.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	91	1.000	Domainoid score	I2614
eggNOG	1	0.900	-	-		E1_KOG2816
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	95	1.000	Inparanoid score	I2229
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D582396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm1054
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23504
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.970