DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11537 and slc2a10

DIOPT Version :9

Sequence 1:	NP_001097489.1	Gene:	CG11537 / 38373	FlyBaseID:	FBgn0035400	Length:	705	Species:	Drosophila melanogaster
Sequence 2:	NP_001072926.1	Gene:	slc2a10 / 780388	XenbaseID:	XB-GENE-950490	Length:	555	Species:	Xenopus tropicalis

Alignment Length:	493	Identity:	103/493 - (20%)
Similarity:	176/493 - (35%)	Gaps:	144/493 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   247 GIGEPSVHHALVVIFLEFFAWGLLTMPIIS----TLNQTFPDHTFLMNGLVMGIKGILSFLSAPL 307
            |:..|::..|..|..|....:| ..:.|||    .|...:....|....||..:  :...|.|.|
Frog     2 GLSSPTLILAATVSLLGGIVFG-YELGIISGALLVLKTVYQLTCFEQEALVSAV--LFGALLASL 63

  Fly   308 IGA-LSDIWGRKFFLLVT-VFFTCLPIPLMSINTWWFFAMISISGAFAVTFSVVFA--YVADVTT 368
            ||. :.|.|||:..:|.: :......|.|::.:|:|:..:..::..||::.|.:..  ||:::..
Frog    64 IGGIIIDRWGRRTAILASNLVVLAGSIILIATSTFWWLIVGRVTIGFAISISSMACCIYVSEIVR 128

  Fly   369 PEERSKAYGLASATFAASLVISPALGNAL-------MEMYGDTLVVALSTAIALLDVFFILVAVP 426
            |.:|.....|........::||.|:...|       ..|:|..:|.|....|::|    .|.:.|
Frog   129 PHQRGMLVSLYETGITVGILISYAMNYFLSGVNESWKYMFGLAIVPAAFQFISIL----FLPSKP 189

  Fly   427 ESLSEKMRPASWGAPISWEQ--ADPFLALRKVGTDKTVLMLCLTVLLSYLPEAGE-----YSCMF 484
            ..|:            .|||  .|.|:.|.:.|                  ||||     |...:
Frog   190 HKLN------------FWEQDTDDGFIELEETG------------------EAGEFKPDTYDRQY 224

  Fly   485 VYLKLKMGFNYVEVSVFIAIVGILSITVQVTLGSFMQVFGAKRTIIMGLALEIVQ-------LLW 542
            .:|.|                             |......:...::||.|.:.|       :|:
Frog   225 TFLDL-----------------------------FRSKDNMRTRTLLGLGLVLFQQFTGQPNVLY 260

  Fly   543 YG---FGSQKWMMWSAGVVAALGSITYPAISAFVSLYAAPESQGAVQGMITGMRGL----CNGLG 600
            |.   |.|..:...|:.|:|::|.......|..:::..|.::         |.|.|    |..:.
Frog   261 YASTIFQSVGFQSNSSAVLASVGLGVVKVASTLIAICFADKA---------GRRILLLAGCIVMT 316

  Fly   601 PAVFGVVFYLFNVDLNDDHDSHAKSSGSRATNVEKISQHVPGPPFVFGALCVFCAIIVSAFIPEG 665
            .|:.|:....|.|.::...|..:.:..:.::....:||       :.|             |...
Frog   317 IAITGIGIVSFTVKMDSHRDCGSVTGRNMSSGESNVSQ-------LLG-------------IVHA 361

  Fly   666 QTSTLEKKRASLDVQYEIEPGHKAPSSLAPLIRSDSLA 703
            :|||:.    :||         .:...||..|||.|||
Frog   362 ETSTIN----TLD---------NSVHQLAMAIRSPSLA 386

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11537	NP_001097489.1	MFS	256..612	CDD:119392	81/391 (21%)
CG11537	NP_001097489.1	MFS_1	257..601	CDD:284993	78/379 (21%)
slc2a10	NP_001072926.1	MFS_GLUT10_Class3	10..517	CDD:340994	101/485 (21%)
		Monosaccharide binding. /evidence=ECO:0000250\|UniProtKB:P11166	250..256		1/5 (20%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	528..555
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910