Protein Alignment CG11537 and SLC46A2

DIOPT Version :9

• Sequence 1: NP_001097489.1
• Gene: CG11537 / 38373
• FlyBaseID: FBgn0035400
• Length: 705
• Species: Drosophila melanogaster
• Sequence 2: NP_149040.3
• Gene: SLC46A2 / 57864
• HGNCID: 16055
• Length: 475
• Species: Homo sapiens
• Alignment Length: 426
• Identity: 92/426 - (21%)
• Similarity: 161/426 - (37%)
• Gaps: 104/426 - (24%)

  Fly   287 FLMNGLVMGIKGILSFLSAPLIGALSDIWGRKFFL---LVTVFFTCLPIPLMSINTW------WF 342
            :::..||:|:..:   |||..:|.|||.:.||..:   |:....:.|.:.|..:..|      ..
Human    78 YIIYNLVVGLSPL---LSAYGLGWLSDRYHRKISICMSLLGFLLSRLGLLLKVLLDWPVEVLYGA 139

  Fly   343 FAMISISGAFAVTFSVVFAYVADVTTPEERSKA--------YGLASATFAASLVISPALGNALME 399
            .|:..:.|.|:..:|.|.| :..:.:.|.|...        .|||.  |..|:    |.|:...:
Human   140 AALNGLFGGFSAFWSGVMA-LGSLGSSEGRRSVRLILIDLMLGLAG--FCGSM----ASGHLFKQ 197

  Fly   400 MYGDT----LVVALSTAIALLDVFF--ILVAVPESLSEKMR--PA-------------------- 436
            |.|.:    ::.|.|.:.|...:.:  :::.||||:::..:  ||
Human   198 MAGHSGQGLILTACSVSCASFALLYSLLVLKVPESVAKPSQELPAVDTVSGTVGTYRTLDPDQLD 262

  Fly   437 ---SWGAPISWEQADPF---LALRKVGTDKTVLMLCLTVLLSYLPEAGEYSCMFVYLKLKMGFNY 495
               :.|.|.|..:|.|.   :||..||.  .:..|.:...:..:|       :|| |:..:|:|.
Human   263 QQYAVGHPPSPGKAKPHKTTIALLFVGA--IIYDLAVVGTVDVIP-------LFV-LREPLGWNQ 317

  Fly   496 VEVSVFIAIVGILSITVQVTLGSFMQVFGAKRTIIMGLALEIVQLLWYGFGSQKWMMWSAGVVAA 560
            |:|...:|....:.||..:.:..|.:.|.....|::|:.......|...|..:.:|.:.|..|..
Human   318 VQVGYGMAAGYTIFITSFLGVLVFSRCFRDTTMIMIGMVSFGSGALLLAFVKETYMFYIARAVML 382

  Fly   561 LGSITYPAISAFVSLYAAPESQGAVQGMITGMRGLCNGLGPAVFGVVFYLFNVDLNDDHDSHAKS 625
            ...|....|            :.|:..:|.|          :.:|.||.:..:.|       |.:
Human   383 FALIPVTTI------------RSAMSKLIKG----------SSYGKVFVILQLSL-------ALT 418

  Fly   626 SGSRATNVEKISQ----HVPGPPFVFGALCVFCAII 657
            ....:|...||.|    ...|..|...:...|.|||
Human   419 GVVTSTLYNKIYQLTMDMFVGSCFALSSFLSFLAII 454

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11537	NP_001097489.1	MFS	256..612	CDD:119392	80/375 (21%)
		MFS_1	257..601	CDD:284993	77/364 (21%)
SLC46A2	NP_149040.3	MFS_1	84..421	CDD:284993	81/385 (21%)
		MFS	<282..453	CDD:304372	42/209 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2816
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810