DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11537 and mfsd14bb

DIOPT Version :9

Sequence 1:	NP_001097489.1	Gene:	CG11537 / 38373	FlyBaseID:	FBgn0035400	Length:	705	Species:	Drosophila melanogaster
Sequence 2:	XP_003199082.1	Gene:	mfsd14bb / 557243	ZFINID:	ZDB-GENE-120215-153	Length:	471	Species:	Danio rerio

Alignment Length:	469	Identity:	275/469 - (58%)
Similarity:	342/469 - (72%)	Gaps:	14/469 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly   244 KSSGIGEPSVHHALVVIFLEFFAWGLLTMPIISTLNQTFPDHTFLMNGLVMGIKGILSFLSAPLI 308
            :...:|...|.||:||||:|||||||||.|:::.|:.|||.||||||||:.|:||:|||:||||:
Zfish     7 RQRSVGRAKVAHAVVVIFMEFFAWGLLTTPMLTVLHDTFPQHTFLMNGLIQGVKGLLSFMSAPLV 71

  Fly   309 GALSDIWGRKFFLLVTVFFTCLPIPLMSINTWWFFAMISISGAFAVTFSVVFAYVADVTTPEERS 373
            |||||:||||.|||:||||||.|||||.|:.|||||::|:||.|:|||||:||||||:|...|||
Zfish    72 GALSDVWGRKSFLLLTVFFTCAPIPLMRISPWWFFALMSVSGLFSVTFSVIFAYVADITEEHERS 136

  Fly   374 KAYGLASATFAASLVISPALGNALMEMYGDTLVVALSTAIALLDVFFILVAVPESLSEKMRPASW 438
            .||||.|||||||||.|||:|..|...|||:|||.|:|.||:||:.|:|:.|||||.:|||.:||
Zfish   137 TAYGLVSATFAASLVTSPAIGAFLSIHYGDSLVVLLATIIAVLDILFVLLVVPESLPDKMRLSSW 201

  Fly   439 GAPISWEQADPFLALRKVGTDKTVLMLCLTVLLSYLPEAGEYSCMFVYLKLKMGFNYVEVSVFIA 503
            |.||||||||||.:|||||.|.|||::|:|||||||||||:||..|:||...:.|:...::.|||
Zfish   202 GFPISWEQADPFASLRKVGKDSTVLLICVTVLLSYLPEAGQYSSFFLYLGQVINFSSAAIAGFIA 266

  Fly   504 IVGILSITVQVTLGS-FMQVFGAKRTIIMGLALEIVQLLWYGFGSQKWMMWSAGVVAALGSITYP 567
            :||||||..|..|.| .|:..|.|.|:::||..::.||.||||||:.||||:||.||||.|||:|
Zfish   267 MVGILSIGAQTLLLSVLMKKIGNKSTVLLGLGFQLFQLAWYGFGSEPWMMWAAGAVAALSSITFP 331

  Fly   568 AISAFVSLYAAPESQGAVQGMITGMRGLCNGLGPAVFGVVFYLFNVDLNDDHDSHAKSSGSRATN 632
            ||||.||.....:.||||||:|||:|||||||||.:||.:|:||||:||   |.....|.|..|.
Zfish   332 AISALVSRCTDRDQQGAVQGIITGIRGLCNGLGPFLFGFIFFLFNVELN---DISTVQSNSAVTP 393

  Fly   633 VEKISQHVPGPPFVFGALCVFCAIIVSAFIPEGQTSTLEKKRASLDVQYEIEP------GHKAPS 691
            ..|....||||||||||..|..|::|:.||| .|.:.|.|..:|.......||      |...|:
Zfish   394 DTKQKSVVPGPPFVFGACTVVLALLVAVFIP-SQPAPLVKTCSSSSTCVVTEPMSSILAGGSLPA 457

  Fly   692 S---LAPLIRSDSL 702
            |   :.||::..||
Zfish   458 SDEDIEPLLQDSSL 471

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11537	NP_001097489.1	MFS	256..612	CDD:119392	233/356 (65%)
CG11537	NP_001097489.1	MFS_1	257..601	CDD:284993	226/344 (66%)
mfsd14bb	XP_003199082.1	MFS	16..365	CDD:119392	229/348 (66%)
mfsd14bb	XP_003199082.1	MFS_1	21..365	CDD:284993	226/343 (66%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575238
Domainoid	1	1.000	510	1.000	Domainoid score	I315
eggNOG	1	0.900	-	-		E1_KOG2816
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	579	1.000	Inparanoid score	I995
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D139531at33208
OrthoFinder	1	1.000	-	-		FOG0001490
OrthoInspector	1	1.000	-	-		otm26206
orthoMCL	1	0.900	-	-		OOG6_102321
Panther	1	1.100	-	-	O	PTHR23504
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1552
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	13	12.760