DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11537 and mfsd14a

DIOPT Version :9

Sequence 1:	NP_001097489.1	Gene:	CG11537 / 38373	FlyBaseID:	FBgn0035400	Length:	705	Species:	Drosophila melanogaster
Sequence 2:	NP_001016552.1	Gene:	mfsd14a / 549306	XenbaseID:	XB-GENE-1001416	Length:	488	Species:	Xenopus tropicalis

Alignment Length:	419	Identity:	271/419 - (64%)
Similarity:	332/419 - (79%)	Gaps:	1/419 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly   247 GIGEPSVHHALVVIFLEFFAWGLLTMPIISTLNQTFPDHTFLMNGLVMGIKGILSFLSAPLIGAL 311
            |||.|||:||::|||||||||||||.|.:..|::|||.||||||||:.|:||:||||||||||||
Frog    30 GIGSPSVYHAVIVIFLEFFAWGLLTAPTLVVLHETFPKHTFLMNGLIQGVKGLLSFLSAPLIGAL 94

  Fly   312 SDIWGRKFFLLVTVFFTCLPIPLMSINTWWFFAMISISGAFAVTFSVVFAYVADVTTPEERSKAY 376
            ||:||||.|||:||||||.|||||.|:.||:||:||:||.||||||||||||||:|...|||.||
Frog    95 SDVWGRKSFLLLTVFFTCAPIPLMKISPWWYFAVISVSGVFAVTFSVVFAYVADITQEHERSMAY 159

  Fly   377 GLASATFAASLVISPALGNALMEMYGDTLVVALSTAIALLDVFFILVAVPESLSEKMRPASWGAP 441
            ||.|||||||||.|||:|..|..:|||.|||.|:|||||||:.||||||||||.|||||||||||
Frog   160 GLVSATFAASLVTSPAIGAYLGRVYGDNLVVLLATAIALLDICFILVAVPESLPEKMRPASWGAP 224

  Fly   442 ISWEQADPFLALRKVGTDKTVLMLCLTVLLSYLPEAGEYSCMFVYLKLKMGFNYVEVSVFIAIVG 506
            |||||||||.:|:|||.|..||::|:||.||||||||:||..|:||:..|.|:...|:.|||::|
Frog   225 ISWEQADPFASLKKVGQDSIVLLICITVFLSYLPEAGQYSSFFLYLRQIMDFSPESVAAFIAVLG 289

  Fly   507 ILSITVQ-VTLGSFMQVFGAKRTIIMGLALEIVQLLWYGFGSQKWMMWSAGVVAALGSITYPAIS 570
            ||||..| |.|...|:..|.|.||::||..:|:||.||||||:.||||:||.|||:.|||:||:|
Frog   290 ILSIIAQTVVLSLLMRSIGNKNTILLGLGFQILQLAWYGFGSEPWMMWAAGAVAAMSSITFPAVS 354

  Fly   571 AFVSLYAAPESQGAVQGMITGMRGLCNGLGPAVFGVVFYLFNVDLNDDHDSHAKSSGSRATNVEK 635
            |.||..|..:.||.|||||||:||||||||||::|.:||:|:|:||:...:..:..|.......:
Frog   355 ALVSRTADADQQGVVQGMITGIRGLCNGLGPALYGFIFYIFHVELNEMPITETEHVGKVTAPKSE 419

  Fly   636 ISQHVPGPPFVFGALCVFCAIIVSAFIPE 664
            .:..:|||||:||:..|..|::|:.||||
Frog   420 QNSIIPGPPFLFGSCSVLLALLVALFIPE 448

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11537	NP_001097489.1	MFS	256..612	CDD:119392	245/356 (69%)
CG11537	NP_001097489.1	MFS_1	257..601	CDD:284993	238/344 (69%)
mfsd14a	NP_001016552.1	MFS_MFSD14	36..447	CDD:340945	263/410 (64%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	498	1.000	Domainoid score	I355
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	575	1.000	Inparanoid score	I1029
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D139531at33208
OrthoFinder	1	1.000	-	-		FOG0001490
OrthoInspector	1	1.000	-	-		otm48121
Panther	1	1.100	-	-	LDO	PTHR23504
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4214
SonicParanoid	1	1.000	-	-		X1552
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	9.190