DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11537 and CG5078

DIOPT Version :9

Sequence 1:	NP_001097489.1	Gene:	CG11537 / 38373	FlyBaseID:	FBgn0035400	Length:	705	Species:	Drosophila melanogaster
Sequence 2:	NP_649238.3	Gene:	CG5078 / 40276	FlyBaseID:	FBgn0037005	Length:	447	Species:	Drosophila melanogaster

Alignment Length:	446	Identity:	251/446 - (56%)
Similarity:	333/446 - (74%)	Gaps:	17/446 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly   240 ICCCKSSGIGEPSVHHALVVIFLEFFAWGLLTMPIISTLNQTFPDHTFLMNGLVMGIKGILSFLS 304
            :....:||||:|||.|.|||:|||:|||||||||:|:||.:|||||||||||||||:||||||||
  Fly    11 VSLASTSGIGKPSVGHILVVVFLEYFAWGLLTMPMIATLKETFPDHTFLMNGLVMGVKGILSFLS 75

  Fly   305 APLIGALSDIWGRKFFLLVTVFFTCLPIPLMSINTWWFFAMISISGAFAVTFSVVFAYVADVTTP 369
            :|||||||||:|||..||:||.||.||||:|:::.||||.:.||||...|:|||.|||||||||.
  Fly    76 SPLIGALSDIYGRKVLLLITVIFTSLPIPMMTMDNWWFFVISSISGVLGVSFSVAFAYVADVTTK 140

  Fly   370 EERSKAYGLASATFAASLVISPALGNALMEMYGDTLVVALSTAIALLDVFFILVAVPESLSEKMR 434
            ||||::|.|.||||||||||:||:||.:|:.||...||.::|.::..:|.|:|:||||:|.:.:|
  Fly   141 EERSRSYELVSATFAASLVIAPAMGNLIMDRYGINTVVLVATLVSTTNVMFVLLAVPETLQQNVR 205

  Fly   435 PASWGAPISWEQADPFLALRKVGTDKTVLMLCLTVLLSYLPEAGEYSCMFVYLKLKMGFNYVEVS 499
            ...    :||:||||||:||:||:|..||:||:.:....||||||||.:..||||.|||::.|:|
  Fly   206 STG----LSWKQADPFLSLRRVGSDPNVLLLCVVMFTFLLPEAGEYSSVPAYLKLTMGFDFTELS 266

  Fly   500 VFIAIVGILSITVQVTLGSFMQVFGAKRTIIMGLALEIVQLLWYGFGSQKWMMWSAGVVAALGSI 564
            ..:|.:.||.|::.|||||.::..|||..||:||.||::||:.:..|.:||.||.||.||||.||
  Fly   267 TLVAFMAILGISINVTLGSIVKTLGAKNAIILGLLLELLQLILFAIGYEKWQMWLAGNVAALSSI 331

  Fly   565 TYPAISAFVSLYAAPESQGAVQGMITGMRGLCNGLGPAVFGVVFYLFNVDLNDDHDSHAKSSGSR 629
            |:||:||:||||...|:|||||||||||.|||:|||||:||:||||.::||:.:.......||.|
  Fly   332 TFPAVSAYVSLYTDVETQGAVQGMITGMSGLCSGLGPALFGIVFYLSDMDLDKNRILIGSVSGDR 396

  Fly   630 -ATNVEKISQHVPGPPFVFGALCVFCAIIVSAFIPEGQTSTLEKKRASLDVQYEIE 684
             .||           ||:.||:.||..|:::::||:.:.|...::..|. ::|.||
  Fly   397 TVTN-----------PFMIGAISVFIGILLASYIPDEKVSRGRREEFSA-LKYIIE 440

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11537	NP_001097489.1	MFS	256..612	CDD:119392	222/355 (63%)
CG11537	NP_001097489.1	MFS_1	257..601	CDD:284993	213/343 (62%)
CG5078	NP_649238.3	MFS	27..375	CDD:119392	218/351 (62%)
CG5078	NP_649238.3	MFS_1	27..368	CDD:284993	213/344 (62%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45470062
Domainoid	1	1.000	91	1.000	Domainoid score	I2614
eggNOG	1	0.900	-	-		E1_KOG2816
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	95	1.000	Inparanoid score	I2229
Isobase	1	0.950	-	0	Normalized mean entropy	S2848
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D139531at33208
OrthoFinder	1	1.000	-	-		FOG0001490
OrthoInspector	1	1.000	-	-		mtm1054
orthoMCL	1	0.900	-	-		OOG6_102321
Panther	1	1.100	-	-	P	PTHR23504
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	11	10.750