DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11537 and Slc18b1

DIOPT Version :9

Sequence 1:	NP_001097489.1	Gene:	CG11537 / 38373	FlyBaseID:	FBgn0035400	Length:	705	Species:	Drosophila melanogaster
Sequence 2:	XP_006227779.1	Gene:	Slc18b1 / 309570	RGDID:	1306962	Length:	455	Species:	Rattus norvegicus

Alignment Length:	506	Identity:	109/506 - (21%)
Similarity:	166/506 - (32%)	Gaps:	170/506 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   215 GGNSEATPERPKRNRFFEWIRVV-CNICCCKSSGIGEPSVHHALVVIFLEFFAWGLLTMPIISTL 278
            ||::..|..|..:.:.|..:... .|:.|                             |...|.|
  Rat    18 GGSTGETSRRLSKEQIFVLVSAASMNLGC-----------------------------MMTYSIL 53

  Fly   279 NQTFP--------DHTFLMNGLVMGIKGILSFLSAPLIGALSDIWGRKFFLL--------VTVFF 327
            ...||        .:|.:  |::.|...:...|::.:.|......|.||..:        ||:.|
  Rat    54 GPFFPKEAEKKGASNTTI--GMIFGCYALFELLASLVFGKYLVHIGAKFMFIAGMFVSGGVTILF 116

  Fly   328 TCL------PIPLMSINTWWFFAMISISGAFAVTFSVVFAYVADVTTPEE-RSKAYGLASATFAA 385
            ..|      ||         |.||     .|.|.......:.|.:|.... .:||:....||...
  Rat   117 GVLDQLPEGPI---------FIAM-----CFLVRIVDAIGFGAAITASSSILAKAFPNNVATVMG 167

  Fly   386 S--------LVISPALGNALMEMYGDTLVVALSTAIALLDVFFILVAVPESLSEKMRPASWGAPI 442
            |        ||..|.||..|.:.:|..:.......|.||.:...|..:|...|:..:.:.|
  Rat   168 SLEVFSGLGLVAGPPLGGLLYQSFGYEVPFIFLGCIVLLMIPLNLCILPSYESDAGKQSFW---- 228

  Fly   443 SWEQADPFLALRKVGTDKTVLMLCLTVLLSYLPEAGEYSC---------MFVYLKLKMGFNYVEV 498
                  ..:.|.|:|     |:..:.:.||        ||         :||..|..:...||.:
  Rat   229 ------KLVTLPKIG-----LIAFVIISLS--------SCFGFLDPTLSLFVMKKFSLSTGYVGL 274

  Fly   499 SVFIA----------IVGILSITVQVTLGSFMQVFGAKRTIIMGLALEIVQLLWYGFGSQKWMMW 553
             ||:.          :.|:||..:. .|..:..|||...|....:.|..:.||  ...||.|::.
  Rat   275 -VFLGLSLSYAISSPLFGLLSDKMP-NLRKWFLVFGNLITAGCYMLLGPIPLL--HIKSQLWLLV 335

  Fly   554 SA----GVVAALGSI-TYP----------------AISAFVSLYAAPESQGAVQGMITGMRG-LC 596
            ..    ||.|.:..| |:|                .:.....|:.|..|.||..|.|.|  | ||
  Rat   336 LVLVINGVSAGMSIIPTFPEMLSCAYANGFEDGISTLGLVSGLFGAMWSVGAFMGPILG--GFLC 398

  Fly   597 NGLG----PAVFGV----------VFYLFNVDLNDDHDSHAKSSGSRATNV 633
            ..:|    .|:.|:          :|||:       .||..:.  |:|.|:
  Rat   399 EKIGFEWAAAIQGLWTLLSGVAMALFYLW-------EDSTMRR--SKAQNI 440

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11537	NP_001097489.1	MFS	256..612	CDD:119392	97/441 (22%)
CG11537	NP_001097489.1	MFS_1	257..601	CDD:284993	92/419 (22%)
Slc18b1	XP_006227779.1	MFS	36..425	CDD:119392	96/462 (21%)
Slc18b1	XP_006227779.1	MFS_1	47..391	CDD:284993	85/386 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910