Protein Alignment CG11537 and vpat-1

DIOPT Version :9

• Sequence 1: NP_001097489.1
• Gene: CG11537 / 38373
• FlyBaseID: FBgn0035400
• Length: 705
• Species: Drosophila melanogaster
• Sequence 2: NP_741716.2
• Gene: vpat-1 / 180457
• WormBaseID: WBGene00018860
• Length: 628
• Species: Caenorhabditis elegans
• Alignment Length: 668
• Identity: 133/668 - (19%)
• Similarity: 233/668 - (34%)
• Gaps: 171/668 - (25%)

  Fly    21 LEDSEAEQVNSPVAIKGEPSAHGDT--DRDGDADRERQE----------SGEQTDSLSTRSSSST 73
            |:...:.:|..|..:     .:|.|  :|.|.....::|          :.:.|..|.||:.|
 Worm    15 LDMDTSSEVYYPTLV-----GYGGTSNERSGSTSAGKKEKKVVSINTADTRKSTQHLKTRNHS-- 72

  Fly    74 PTTADVADVETISSLPLSPPA--------FGGRGNQLVKRHSPLKDKQAEQADSSSSSSCSQQPD 130
              |::..|.|.   .||..|:        :.|........|:|....::|......:....::|.
 Worm    73 --TSNAIDNEL---TPLLHPSISLPTVVGYDGFNEDYQAGHNPPTTTRSEIGPREFARKKRRRPR 132

  Fly   131 ADDVPTVSGCDLRQSP------PSSSSSSSSTSTSPQTSRYAAAAAHPSAAFAETAITASSGSGR 189
            .:   |:.|.:.::.|      |....|:..:...|::|..:|...:.|.| ...:|..|.||
 Worm   133 FN---TLQGLNRKKKPRPFIISPFMPISTQISVDGPRSSALSAKINYESTA-ERLSIKESEGS-- 191

  Fly   190 VCGGSGGAAHRRTHSAASYISMRSQGGNSEATPERPKRNRFFEWIRVVCNICCCKSSGIGEPSVH 254
                   .:.....||.|        ...:|.|          :::...:.....||
 Worm   192 -------ESDSDEESAIS--------DEEQAVP----------FLKSALHTVSALSS-------- 223

  Fly   255 HALVVIFLEFFAWGLLTMPIISTLNQTFPDHTFLMN------GLVMGIKGILSFLSAPLIGALSD 313
            ..|:.|.:...| .|.:....|.:...:|....|.|      |:|.||.....|:.:||.|....
 Worm   224 RQLLSISMLSLA-NLCSTIAFSCIAPFYPAEAKLKNLSETQTGIVFGIFEFTMFIISPLFGKYII 287

  Fly   314 IWGRKFFLLVTV-----------FFTCLPIPLMSINTWWFFAMI-----SISGAFAVTFSVVFAY 362
            ..|.:...:|.:           |...||    |.||:::|:::     ::..|..||.|  ||
 Worm   288 FIGARTMFIVGIAVTGVTAILFGFLNFLP----SGNTFFWFSVLVRILEAVGDAAFVTSS--FA- 345

  Fly   363 VADVTTPEERSKAYGLASATFAASLVISPALGNALMEMYG---DTLVVALSTAIALLDVFFIL-- 422
            :|..:.|:..:...|:............|.:|....::.|   ..||:.:...:|.:..||::
 Worm   346 IAAKSFPKNVAFVVGILETFAGLGYTAGPVIGGFFYDIGGFQLPFLVLGIVLLVASVLAFFLIEN 410

  Fly   423 ----VAVPE--SLSEKMR-PASW-------GAPISWEQADPFLALRKVGTDKTVLMLCLTVLLSY 473
                .:.||  .:.|.:| |..|       ...||....||.|:               ..|.|:
 Worm   411 TKDDESNPEDKGMLEILRLPQIWLPIFSVVSCAISLSFLDPTLS---------------NHLESF 460

  Fly   474 LPEAGEYSCMFVYLKLKMGFNYVEVSVFIAIVGILSITVQVTLGSFMQVFGAKRTIIMGLALEIV 538
            .....|...||:   |..||..|...||.||:.      ::..|..:.:||:..|::....:...
 Worm   461 KLTPTEIGLMFL---LCGGFYTVMCPVFGAIMD------RLHNGENLLLFGSIATLLSMFFIGPT 516

  Fly   539 QLLWYGFGSQKWMMWSAGV-VAALGSITYPAISAFVSLYAAP-------------ESQGAVQGMI 589
            .|| .|:..:.  :|..|: :|.||   ..|.:.::..:...             .:.|.|.|:.
 Worm   517 PLL-NGYVEKD--LWVIGISLAVLG---LAASALYIPCFQMCLDEVKDKGFDDNFHTYGCVSGIF 575

  Fly   590 TGMRGLCNGLGPAVFGVV 607
            ....|..:.:|| .||.|
 Worm   576 QAAFGFGSFIGP-TFGSV 592

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11537	NP_001097489.1	MFS	256..612	CDD:119392	88/407 (22%)
		MFS_1	257..601	CDD:284993	83/398 (21%)
vpat-1	NP_741716.2	MFS_SLC18B1	229..621	CDD:340943	87/403 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910