DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11537 and AgaP_AGAP012382

DIOPT Version :9

Sequence 1:	NP_001097489.1	Gene:	CG11537 / 38373	FlyBaseID:	FBgn0035400	Length:	705	Species:	Drosophila melanogaster
Sequence 2:	XP_320176.3	Gene:	AgaP_AGAP012382 / 1280332	VectorBaseID:	AGAP012382	Length:	497	Species:	Anopheles gambiae

Alignment Length:	493	Identity:	104/493 - (21%)
Similarity:	167/493 - (33%)	Gaps:	167/493 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   233 WIRVVCNICCCKSSGI------GEPSVHHALVVI--FLEFFAWGLLT---MPIISTLNQTFPDHT 286
            |.|||.|. ..:|||:      .|..:...||.:  ||.|.::|::|   .|.:..::.|. ...
Mosquito     7 WWRVVQNE-KDRSSGLESDFEYRERWITIRLVYVSGFLMFLSFGVVTTGLWPYLQDMDPTV-GKP 69

  Fly   287 FLMNGLVMGIKGILSFLSAPLIG----ALSDIWGRKFFLLVTVFFT----------CLPIPLMSI 337
            ||.........|.|.|  :||||    .||.|  |..|:::|..|.          ..|.|...
Mosquito    70 FLSVVFAAPPAGQLIF--SPLIGWCSNRLSSI--RVPFVILTALFVFGNGLYSVVELFPTPHRR- 129

  Fly   338 NTWWFFAMISISGAFAVTFSV---VFAYVADVTTPEERSKAYGLASATFAASLVISPALGNAL-- 397
                 :.::.....|.::.|:   ..||::..|...||:.|..::|......|.:.|.:..||
Mosquito   130 -----YVLLLARFVFGISTSINTLSRAYISTATKLSERTGAISMSSLAQTFGLAVGPIIQAALST 189

  Fly   398 ------------MEMYGDTLVVALSTAIALLDVFFI--------LVAVPESLS-----------E 431
                        :.||  |:...:..|:.::.:.|:        .:|..|::.           |
Mosquito   190 IGKEGLMWYGLRINMY--TMAGWICAALGVVYILFLNPSCFVHRTIAAQEAMKTTGFSKATDTYE 252

  Fly   432 KMRPAS-WG-------------------APIS-----WEQADPFLALRKVGTDKTVLMLCLTVLL 471
            .::..| |.                   :|||     |...:....|..:.|..|   ||...:.
Mosquito   253 PLKMFSIWTVMIGYSVLMFFYVSVQTALSPISLDQFGWSHEESLYYLGILITGGT---LCSCAVF 314

  Fly   472 SYLPEAGEYSCMFVYLKLKMGFNYVEVSVFIAIVGI-LSITVQVTLGS----FMQVFGAKRTIIM 531
            ..||:            |...|....|.:|.|||.: :|..|.:.:||    .:.....:.|.:.
Mosquito   315 LLLPQ------------LCKRFQEHNVFLFFAIVPLFISQVVMIPMGSKSIPMLDSSNNRSTGVG 367

  Fly   532 GLALEIVQLLWYGFG---SQKW--------------------MMWSAGVVAALGSITYPAIS-AF 572
            |           |.|   .|:|                    :.:|.|:          ||| ..
Mosquito   368 G-----------GGGCPIEQEWCNSIPPINQYQLTISYTMLCISFSVGI----------AISQTI 411

  Fly   573 VSLYAAPESQGAVQGMITGMRGLCNGLGPAVFGVVFYL 610
            :|.......||....:.|.:.||...:|||  .||.|:
Mosquito   412 LSKLLGTRPQGNWMALYTSIGGLTRIIGPA--SVVVYV 447

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11537	NP_001097489.1	MFS	256..612	CDD:119392	95/464 (20%)
CG11537	NP_001097489.1	MFS_1	257..601	CDD:284993	89/452 (20%)
AgaP_AGAP012382	XP_320176.3	MFS	34..470	CDD:119392	95/465 (20%)
AgaP_AGAP012382	XP_320176.3	MFS_1	37..440	CDD:284993	88/451 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910