Protein Alignment CG11537 and SLC46A1

DIOPT Version :9

• Sequence 1: NP_001097489.1
• Gene: CG11537 / 38373
• FlyBaseID: FBgn0035400
• Length: 705
• Species: Drosophila melanogaster
• Sequence 2: NP_542400.2
• Gene: SLC46A1 / 113235
• HGNCID: 30521
• Length: 459
• Species: Homo sapiens
• Alignment Length: 555
• Identity: 110/555 - (19%)
• Similarity: 185/555 - (33%)
• Gaps: 197/555 - (35%)

  Fly   218 SEATPERPKRNRFFEWIRVVCNICCCKSSGIGEPSVHHALVVIFLE-----FFAWGLL------- 270
            |.:.||:|:       .|....:.|   .|..||.|..|...:.|:     .:.|...
Human     4 SASPPEKPR-------ARPAAAVLC---RGPVEPLVFLANFALVLQGPLTTQYLWHRFSADLGYN 58

  Fly   271 ---------------TMPIISTLNQTFPDHTFLMN--GLVMGIKGILSFLSAPLIGALSDIWGRK 318
                           ||..:.||...:   |..||  |.::|:      .|:.|:||.||..||:
Human    59 GTRQRGGCSNRSADPTMQEVETLTSHW---TLYMNVGGFLVGL------FSSTLLGAWSDSVGRR 114

  Fly   319 FFL-----------LVTVFFTCLPIPLMSINTWWFF---AMISISGAFAVTFSVVFAYVADVTTP 369
            ..|           ||:||     :..:.::..:|.   .:.::.|.|....:..||.||||::.
Human   115 PLLVLASLGLLLQALVSVF-----VVQLQLHVGYFVLGRILCALLGDFGGLLAASFASVADVSSS 174

  Fly   370 EERSKAYGLASATFAASLVISPALGNALM--EMYGDTLVVALSTAIALLDVFFILVAVPESLSEK 432
            ..|:....|..|:...:.:::..||...:  :.|.:...:||:..||:  ..:......|:|.|
Human   175 RSRTFRMALLEASIGVAGMLASLLGGHWLRAQGYANPFWLALALLIAM--TLYAAFCFGETLKE- 236

  Fly   433 MRPAS---------------WGAPISWEQADPFLALRKVGTDKTVLMLCLTV------------- 469
              |.|               :.||.. |::...|||..:     .:.:.:||
Human   237 --PKSTRLFTFRHHRSIVQLYVAPAP-EKSRKHLALYSL-----AIFVVITVHFGAQDILTLYEL 293

  Fly   470 ---------LLSYLPEAGEYSCMFVYLKLKMGFNYVEVSVFIAIVGILSITVQVTLGSFMQVFGA 525
                     |:.|...|.....:...|.||: ..|.....::|.:
Human   294 STPLCWDSKLIGYGSAAQHLPYLTSLLALKL-LQYCLADAWVAEI-------------------- 337

  Fly   526 KRTIIMGLALEIVQLLWYGFGSQKWMMWSAGVVAALGSITYPAISAFVSLYAAPESQGAV----- 585
                  |||..|:.::.:.|.:...:|::...:..|..:..|.|.|.:|.......|||:
Human   338 ------GLAFNILGMVVFAFATITPLMFTGYGLLFLSLVITPVIRAKLSKLVRETEQGALFSAVA 396

  Fly   586 ----QGMITGMRGLCNGLGPAVFGVVFYLFNVDLNDDHDSHAKSSGSRATNVEKISQHVPGPPFV 646
                ..|:|. .|:.|.|.||.           ||                      .:.|.||:
Human   397 CVNSLAMLTA-SGIFNSLYPAT-----------LN----------------------FMKGFPFL 427

  Fly   647 FGA-LCVFCAIIVSAFIPEGQTSTLEKKRASLDVQ 680
            .|| |.:..|:::         ..|||....|:.|
Human   428 LGAGLLLIPAVLI---------GMLEKADPHLEFQ 453

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11537	NP_001097489.1	MFS	256..612	CDD:119392	86/446 (19%)
		MFS_1	257..601	CDD:284993	83/434 (19%)
SLC46A1	NP_542400.2	MFS	73..443	CDD:119392	92/464 (20%)
		MFS_1	94..407	CDD:284993	70/362 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2816
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810