Protein Alignment CG11537 and MFSD10

DIOPT Version :9

• Sequence 1: NP_001097489.1
• Gene: CG11537 / 38373
• FlyBaseID: FBgn0035400
• Length: 705
• Species: Drosophila melanogaster
• Sequence 2: XP_024309639.1
• Gene: MFSD10 / 10227
• HGNCID: 16894
• Length: 491
• Species: Homo sapiens
• Alignment Length: 510
• Identity: 112/510 - (21%)
• Similarity: 175/510 - (34%)
• Gaps: 170/510 - (33%)

  Fly   215 GGNSEATPERPKRNRFFEWIRVVCNICCCKSSGIGEPSVHHALVVIF----LEFFAWGLLTMPII 275
            ||....||..|...                     :|.....:.|:|    |:..|:.|| :|::
Human     4 GGGGGCTPRPPIHQ---------------------QPPERRVVTVVFLGLLLDLLAFTLL-LPLL 46

  Fly   276 STLNQTFPD----------------------------HTFLMNGLVMGIKGILSFLSAPLIGALS 312
            ..|.::...                            ::.|..||:.....:|.||.|||.||.|
Human    47 PGLLESHGRAHDPLYGSWQGGVDWFATAIGMPVEKRYNSVLFGGLIGSAFSVLQFLCAPLTGATS 111

  Fly   313 DIWGRKFFLLVTVFFTCLPIPLMSINTW-------WFFAMISISGAFAVTFSVVFAYVADVTTPE 370
            |..||:     .|...||.....|...|       .|.|...|.|......|:..|.|||:.:|.
Human   112 DCLGRR-----PVMLLCLMGVATSYAVWATSRSFAAFLASRLIGGISKGNVSLSTAIVADLGSPL 171

  Fly   371 ERSKAYGLASATFAASLVISPALGNAL-MEMYGDTLVVALSTAIALL----DVFFILVAVPESLS 430
            .||:...:....|:....:.|.||.:| :||         :...|||    |:.||...:||:|.
Human   172 ARSQGMAVIGVAFSLGFTLGPMLGASLPLEM---------APWFALLFAASDLLFIFCFLPETLP 227

  Fly   431 -EKMRPA-SWGAPISWEQADPFLALR---------------KVGTDKTV------------LMLC 466
             ||..|: :.|...:.:...|...||               |..|:.:|            |..|
Human   228 LEKRAPSIALGFRDAADLLSPLALLRFSAVARGQDPPSGDSKDSTNPSVEPALPWASPGGALPCC 292

  Fly   467 LTVL--------LSYLPEAGEYSCMFVYLKLKMGFNY--------------VEVSVFIAIVGILS 509
            ..:|        ||.|...|  ...|:||.|..|..|              ::......::|:..
Human   293 GRLLSTRHLSPGLSSLRRLG--LVYFLYLFLFSGLEYTLSFLTHQRFQFSSLQQGKMFFLIGLTM 355

  Fly   510 ITVQVTLGSFM-------QVFGAKRTIIM----------GLALEI--VQLLWYGFGSQKWMMWSA 555
            .|:|   |::.       :|...||.:::          |.:|.:  :.||.|.|.:
Human   356 ATIQ---GAYARRIHPGGEVAAVKRALLLLVPAFLLIGWGRSLPVLGLGLLLYSFAA-------- 409

  Fly   556 GVVAALGSITYPAISAFVSLYAAPESQGAVQGMITGMRGLCNGLGPAVFGVVFYL 610
                   ::..|.:|:.|:.|.:|..:|.|.|.:..:..|....||.|...|::|
Human   410 -------AVVVPCLSSVVAGYGSPGQKGTVMGTLRSLGALARAAGPLVAASVYWL 457

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11537	NP_001097489.1	MFS	256..612	CDD:119392	106/469 (23%)
		MFS_1	257..601	CDD:284993	101/457 (22%)
MFSD10	XP_024309639.1	MFS_1	85..448	CDD:311564	93/396 (23%)
		MFS	90..225	CDD:328737	45/148 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165142524
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840