DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11537 and ptprf

DIOPT Version :9

Sequence 1:	NP_001097489.1	Gene:	CG11537 / 38373	FlyBaseID:	FBgn0035400	Length:	705	Species:	Drosophila melanogaster
Sequence 2:	XP_031756782.1	Gene:	ptprf / 100493254	XenbaseID:	XB-GENE-495325	Length:	1920	Species:	Xenopus tropicalis

Alignment Length:	263	Identity:	57/263 - (21%)
Similarity:	97/263 - (36%)	Gaps:	81/263 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   494 NYVE----VSVFIAIVGILSITVQVTLGSFMQVFGAKR--TIIMGLALEIVQLL-----WYGFGS 547
            ||::    .:.:||..|.|..|:.    .|.::...:|  ||:|...||....:     |.|.||
Frog  1422 NYIDGYRKQNAYIATQGPLPETIT----DFWRMVWEQRTATIVMMTRLEEKSRVKCDQYWPGRGS 1482

  Fly   548 QKWMMWSAGVVAALGSITYPAISAFVSLY---------------------AAPESQGAVQGMITG 591
            :.:.|....::..:...|| .:..| :||                     ..||....:.|.:..
Frog  1483 ETYGMIQVTLMDTVELATY-TVRTF-TLYKNGSSEKRDVRQFQFMAWPDHGVPEYPTPILGFLRR 1545

  Fly   592 MRGLCN--GLGPAV------------FGVV-FYLFNVDLNDDHDSHAKSSGSRATN---VEKISQ 638
            ::| ||  ..||.|            |.|: ..|..|.|....|.:...:..|:..   |:...|
Frog  1546 VKG-CNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERVKLEKTVDIYGHVTCMRSQRNYMVQTEDQ 1609

  Fly   639 HVPGPPFVFGAL--CVFCAII-VSA-----------FIPEGQTSTLEKKRASLDVQYEIEPGHKA 689
            ::    |:..||  .|.|.|. |.|           .:|.|::.|      |:::::::....||
Frog  1610 YI----FIHEALLEAVMCGITEVPARSLYAHIQKLSQVPPGESVT------SMELEFKLLANSKA 1664

  Fly   690 PSS 692
            .:|
Frog  1665 HTS 1667

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11537	NP_001097489.1	MFS	256..612	CDD:119392	36/164 (22%)
CG11537	NP_001097489.1	MFS_1	257..601	CDD:284993	30/140 (21%)
ptprf	XP_031756782.1	I-set	30..121	CDD:400151
		Ig strand A	30..33	CDD:409353
		Ig strand A'	39..42	CDD:409353
		Ig strand B	47..54	CDD:409353
		Ig strand C	60..65	CDD:409353
		Ig strand C'	68..70	CDD:409353
		Ig strand D	77..81	CDD:409353
		Ig strand E	83..90	CDD:409353
		Ig strand F	100..108	CDD:409353
		Ig strand G	111..121	CDD:409353
		IgI_2_RPTP_IIa_LAR_like	133..229	CDD:409400
		Ig strand B	149..153	CDD:409400
		Ig strand C	162..166	CDD:409400
		Ig strand E	193..197	CDD:409400
		Ig strand F	207..212	CDD:409400
		Ig strand G	219..222	CDD:409400
		IgI_3_RPTP_IIa_LAR_like	238..319	CDD:409401
		Ig strand B	252..256	CDD:409401
		Ig strand C	265..269	CDD:409401
		Ig strand E	286..290	CDD:409401
		Ig strand F	298..303	CDD:409401
		Ig strand G	311..314	CDD:409401
		FN3	322..411	CDD:238020
		FN3	418..510	CDD:238020
		FN3	515..603	CDD:238020
		fn3	611..698	CDD:394996
		FN3	713..818	CDD:238020
		FN3	823..904	CDD:238020
		fn3	921..1002	CDD:394996
		fn3	1018..1077	CDD:394996
		R-PTPc-F-1	1348..1623	CDD:350474	46/211 (22%)
		R-PTP-F-2	1626..1915	CDD:350477	9/48 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165162163
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23504
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.030