Protein Alignment promL and prom1b

DIOPT Version :10

• Sequence 1: NP_647770.1
• Gene: promL / 38372
• FlyBaseID: FBgn0026189
• Length: 1013
• Species: Drosophila melanogaster
• Sequence 2: XP_073775965.1
• Gene: prom1b / 378834
• ZFINID: ZDB-GENE-031003-1
• Length: 907
• Species: Danio rerio
• Alignment Length: 1047
• Identity: 203/1047 - (19%)
• Similarity: 382/1047 - (36%)
• Gaps: 268/1047 - (25%)

  Fly    67 WRKGYV---GHGTTHEQLGQPH--WPP----------------VQYTVYRPTTNYTKAPPPPTSA 110
            |:.|.|   ..|.|..:..:.|  .||                |...||.....|...|
Zfish     5 WKVGLVLVMFWGLTSSEDREEHRESPPRTAMLRAPVETLDFGFVPSVVYETHAYYEPGP------ 63

  Fly   111 MNPIFNFTH-FLYDKVLYRDEPIPEGYIV---------VKNSDTLSLGPKVEENDWRDLLAHYWM 165
            |..:|:..| |||   :.:..|.|:..||         :|..|.     |..||....|...|:.
Zfish    64 MGILFHMVHAFLY---VVQPNPFPKDLIVKMVQQNMGGIKGDDY-----KKPENVVLLLQTIYYE 120

  Fly   166 V--LIWVVILVVLIIVIPFIAVCYCCFCCCRRCRQGCPPCTSKQDAQRRFCCGICL-----LILI 223
            :  ::..|:.|..::::|.:.:|:|...||..|        ..:..||:...|.||     ..||
Zfish   121 LGFIVLSVLGVFFVLLMPIVGLCFCVCRCCENC--------GGEMHQRQKKNGDCLRGFYMATLI 177

  Fly   224 IGLIF---GIIIAFVTNKMIDSGFAETSETMKRGSED---------------TCTY-------LK 263
            ...:|   |:.:|:|.|:.|.|....|...:.....|               |..|       |.
Zfish   178 ATSVFLAVGVTVAYVANQNITSQIKSTRRLVSTNIRDLKAFANYTPAQIDYLTAQYTTAKNKVLS 242

  Fly   264 DVADHVHHLM---MYNYEEMETHVLDQLTHAHRHIFLDLSDTSESNSLAEMERVLENMPEALELM 325
            |: |::..|:   ::|  ::|:.|:..|.||.|...:.:.  |...::.|.:..||::..:||.:
Zfish   243 DL-DNIGTLLGGQIHN--KLESEVVPALDHALRMTAVKVE--SAIKAMRETKESLESVSTSLETL 302

  Fly   326 RQ-VEKMEKDLRFYGSQLRDGVRGIKRDVNFAVANLCQLQMCQKFLISSNIEHIDSSQCLHFDNL 389
            :: ..:::..|:.....|.:.:.      ::|.:|......|..  |...:..:..|  .:|:.|
Zfish   303 QEGTGRLQVSLQSERVSLSNTLN------DWACSNEDVTHTCNS--IRGTLNQLALS--ANFNGL 357

  Fly   390 PNTKEFVEGMENIVASEYYAIPQRGLSRLKKVSDKVKTQLSFVVPPMMRDLTKGRTIFREHATNV 454
            |:.:..:..::.::.::...|.|:|.|....            .|.::|:.|||       ..:.
Zfish   358 PDVEAPLANLDAVLKTDLSNIVQKGYSSFND------------TPQLVREQTKG-------IVSA 403

  Fly   455 RNIVEGVLSDIHIKTLHSTKSF--EDVYERFG-----HDRNVVS----------------LIVCL 496
            ...|:|:|.....:.:..||.|  |...:.|.     ..:|:.:                :::|.
Zfish   404 LPKVKGLLDKSGAEIIGFTKMFPVEPALQNFSKFLTDSQKNIEAYYPQIDQLDFYRWIGCVLICC 468

  Fly   497 LILLVLFILIFALLCGCFGRRR----TGYGDECCSKSTGATCLLLAILLIFCVFSFIALVGLFY- 556
            |::|||......||||..|..:    |..|   |..:||...|:.::...| :||:: |:|:..
Zfish   469 LVVLVLAFNFLGLLCGSCGYDKNSTPTTRG---CLSNTGGNLLMASVGFSF-IFSWV-LMGVVVT 528

  Fly   557 -FMLGMVTYQGACAPLRDQENNTLFRQLDASIDLNHYLPPSESN-------KEVVQPLKMSSAIK 613
             |::|....:..|.||.:       ||:...||..:.:.|::.|       ::....|.:.|..:
Zfish   529 TFIVGGNIEKLVCEPLAN-------RQIFKIIDTPYMVHPTKKNFLPGMLFQDPNIDLTIGSMYR 586

  Fly   614 ACHANQTIFDMMRQHNIYDINDLTRIKVMSHSQENTDSIKVFDEDLSTVVLLTKEERDELKTAGE 678
            .|:.|..::..::....::.|......|.  :.|..|.....:.||..::||.:|.:|.|.....
Zfish   587 DCYENNGLYSALQLETKFNFNKFLNATVF--NPEIGDIFNNVNVDLQGMLLLEQEGKDNLIDFAN 649

  Fly   679 SKLAKYHSSLYMPSLCTQFTPMNLNALSEQLYKLSNDLEYPAYGWAKVSFWN----EGLNTKAFY 739
            :.:.......|:       |.:|.......|...:|:|:..|....:.:..|    ...:.:..:
Zfish   650 TGIGDIDYQAYL-------TEVNKGVTVVDLLSYANELDAQADNLPRGALENALKGHASSIRQIH 707

  Fly   740 RNFVPKLTSLVEKMKANLKKIDELISYENHDFTNTIKILTA-TAINSEQFIQTRGKDYINALGGN 803
            ::.|..:...::.:||.......:...|.......:|:... .||.:.:::          :..|
Zfish   708 KDQVVPMEQAMKFVKARSNLNQSIRQLEKTSRELPVKVTNVLNAIEAAEYL----------ISNN 762

  Fly   804 LTNSIDQMIDDYIDMII---KEANESVGH--------CAPLSYIYYRGVDLICHRIVDPINGFWV 857
            .::.:.|..|.:|..||   .:..|.|.|        |.|:|.|......:.|..|||.:|.||.
Zfish   763 ASHVVKQESDKFIKKIIGYFSQYTEWVKHSLAMEVAQCKPISNIVDSAEIVACSFIVDSVNTFWF 827

  Fly   858 GILLCALLFLPILFVAHRLMCLYKKIYPYLATVGAAGVVEGGSDYLYDAYSERDREHVPLANVPK 922
            |:..|.:|.:|.:.::.:|...|
Zfish   828 GLGGCCVLLIPSIIMSVKLAKFY------------------------------------------ 850

  Fly   923 KRRKAYERRREQQDYFEDASPSVSRGNRSGGDRGGGGGDGAPGSSSMRYNDMAPTHWDHEPPRYH 987
                   ||.:.:|.|:|:...|..|..:....|..             |.|..::..::..|::
Zfish   851 -------RRMDTEDVFDDSMDVVVSGCHNEPLYGIN-------------NPMMSSYPSYDTMRWY 895

  Fly   988 NPPAAPP 994
            ...:|||
Zfish   896 PRASAPP 902

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
promL	NP_647770.1	Prominin	76..881	CDD:461660	184/920 (20%)
prom1b	XP_073775965.1	None