Protein Alignment CG45067 and Prom1

DIOPT Version :9

• Sequence 1: NP_001334707.1
• Gene: CG45067 / 38371
• FlyBaseID: FBgn0266437
• Length: 881
• Species: Drosophila melanogaster
• Sequence 2: XP_008768433.1
• Gene: Prom1 / 60357
• RGDID: 69367
• Length: 866
• Species: Rattus norvegicus
• Alignment Length: 898
• Identity: 198/898 - (22%)
• Similarity: 332/898 - (36%)
• Gaps: 261/898 - (29%)

  Fly    47 PQNRYAEPESRSNNGDADSMCPITYLSHVFTGSVVSYAKEVPKGYISKDGNDIGSKVQEDDWEAY 111
            |...| |.:...|.|..|   |:..:.|:|..  |....:.|:        |:..|:.:..::..
  Rat    37 PTTEY-ETQDTFNAGIID---PLYQMVHIFLN--VVQPNDFPQ--------DLVKKLIQKRFDIS 87

  Fly   112 LASQKGLKILVLLLVLLF----LLILILGLLYA----------CCCVAWEK-------NERSSRG 155
            :.:::...|::.|.|.::    |:.:|||||:.          |.|....|       .::.:..
  Rat    88 VDTKEPENIVLALKVAIYEIGVLICVILGLLFIFLMPLVGFFFCMCRCCNKCGGEMHQRQKQNES 152

  Fly   156 C-RYCCGILLAILALLMLLFLILAIMAATQLNI-----------NLKNLKASGCYPSNSSQSSAD 208
            | |.|..|.|.::.|||.|.:....:|..|...           |.::|:|.    ...:....|
  Rat   153 CRRKCLAISLLLICLLMSLGIAFGFVANQQTRTRIQRTQKLAESNYRDLRAL----LTEAPKQID 213

  Fly   209 YIF-------QKASERLRHLYVINYDQKV-KRIKSALNQDPSIKYPNRELEVHAKAIERLIEVLR 265
            ||.       .||...|..:     |..: .|||..|.  |.:.....|::..|.||.:..:.|:
  Rat   214 YILGQYNTTKNKAFSDLDSI-----DSVLGGRIKGQLK--PKVTPVLEEIKAMATAIRQTKDALQ 271

  Fly   266 NMRRIKPVMLRIKNRLLDARRLATQFRDALRGVKRDLMVILIA-DCTHSECQDFYRANEIKMLDM 329
            ||          .:.|...|..:||....|..|:..:...|.: ||..........:...::.::
  Rat   272 NM----------SSSLKSLRDASTQLSTNLTSVRNSIENSLNSNDCASDPASKICDSLRPQLSNL 326

  Fly   330 GCLHYDS-LPEFEPLLESVQEVIDSKFIDYPLQAVGQLRRMSSAIKNRMSDILDSVNKDLNKGAK 393
            |..|..| ||..:..|.:|.:|..:.......:....:..:.:.|:|:..|::..|.|.|:..:.
  Rat   327 GSNHNGSQLPSVDRELNTVNDVDRTDLESLVKRGYMSIDEIPNMIQNQTGDVIKDVKKTLDSVSS 391

  Fly   394 KLQERYEA--SLKVLRQVVEEMKKDMPLVVKTNPRSRSTPAADLRRKLGSSWFGTTLCLIVLLML 456
            |::...::  ..:||.|....:......:.::.||.         .:..|.|:...|.:..||.|
  Rat   392 KVKNMSQSIPVEEVLLQFSHYLNDSNRYIHESLPRV---------EEYDSYWWLGGLIVCFLLTL 447

  Fly   457 VPLLLLFGLLIALFS-PKVA----------------------SWLLCAVLVALFILFSVGVILVL 498
            :......|||..:|. .|.|                      |:|.|.:|          :|||:
  Rat   448 IVTFFYLGLLCGVFGYDKRATPTRRGCVSNTGGIFLMAGVGFSFLFCWIL----------MILVV 502

  Fly   499 FYLVHGALIYQAFCSRKFPQPVDNKSI------------------------NPNKFLPENVTTFR 539
            ...|.||.:.:..|     :|.:||.:                        ||:    .|:|
  Rat   503 LTFVVGANVEKLLC-----EPYENKKLLQVLDTPYLLNDQWQFYLSGILLKNPD----INMT--- 555

  Fly   540 SMPMVRTSEILQSCVRNESLY------NVLGIKEIYDPYGFRDDVMIDVVKSLEKMGNTSMPGAP 598
                  ..::.:.|.|...:|      ||..|.|.::    .:.:..|:||.|||:
  Rat   556 ------FEQVYRDCKRGRGVYATFQLENVFNITENFN----IERLSEDIVKELEKL--------- 601

  Fly   599 KEIHPDAEESAKKLLTGNLSTYDIK-------DYTKYICPQLVPEPNPGPLDGLT--RKLESLAN 654
             .::.|:.|...|  ||..|..|..       :|:.|:  |...:| |..:|.||  ..||:.||
  Rat   602 -NVNIDSIELLDK--TGRKSLEDFAQSGIDRINYSMYL--QEAEKP-PTKVDLLTFASFLETEAN 660

  Fly   655 KVEPGVTLKN----QAIHLRA-YQKHLCVPLAAIVQRLIKRLKQMDWLLSGGYGSFVKYLHHLLD 714
            ::..| .||.    .|.::|| :|:|  ||   .||:.:..|||..|
  Rat   661 QLPDG-NLKQAFLMDAQNIRAIHQQH--VP---PVQQSLNSLKQSVW------------------ 701

  Fly   715 KIKQGDDLLRQDSKKEADEVAR--------------NISKLV-----KSG------LDDYVRVVE 754
                   .|:|.|.|..:||.:              |:|.:|     |.|      .:.|::.|.
  Rat   702 -------ALKQTSSKLPEEVKKVLASLDSAQHFLTSNLSSIVIGETKKFGRTIIGYFEHYLQWVL 759

  Fly   755 EATKEDMESCEPLIREDDEAMVEYADLCNRIAKPMNAIWFWLLLFSSLLLPTI 807
            .|..|.|.||:|:|...|.|:  ...||:.:|.|:|..||.:...:.||||.:
  Rat   760 YAITEKMTSCKPMITAMDSAV--NGILCSYVADPLNLFWFGIGKATMLLLPAV 810

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG45067	NP_001334707.1	None
Prom1	XP_008768433.1	Prominin	18..821	CDD:398888	198/898 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166354198
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG46440
OrthoDB	1	1.010	-	-		D1129032at2759
OrthoFinder	1	1.000	-	-		FOG0002387
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22730
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1580
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.960