Protein Alignment CG45067 and prom

DIOPT Version :10

• Sequence 1: NP_001334707.1
• Gene: CG45067 / 38371
• FlyBaseID: FBgn0266437
• Length: 881
• Species: Drosophila melanogaster
• Sequence 2: NP_001137754.1
• Gene: prom / 246493
• FlyBaseID: FBgn0259210
• Length: 1235
• Species: Drosophila melanogaster
• Alignment Length: 879
• Identity: 157/879 - (17%)
• Similarity: 296/879 - (33%)
• Gaps: 314/879 - (35%)

  Fly   115 QKGLKILVLLLVLLFLLILILGLLYAC----------------CCVAWEKNERSSRGCRYCCGIL 163
            :.|...|:.:..:|.|:.||....:.|                |.:..|..|.|.| ||...|
  Fly   120 ESGFIALMSVFAILALVPLIATCAWCCGRRSTQEEVDHIRNAPCHIRDESLEESLR-CRKSAG-- 181

  Fly   164 LAILALLMLLFLILAIMAATQLNINLKNLKASGCYPSNSSQSSADYIFQKASERLRHLYVINYDQ 228
               |..|.::|::|.:                           :|:....|:.||.    ...:.
  Fly   182 ---LVTLWVVFILLTL---------------------------SDFSIFYANSRLS----AGIEM 212

  Fly   229 KVKRIKSALNQDPSIKYPNRELEVHAK-------AIERLIEVLRNMRRI--KPVM---------- 274
            ..:.:|||:: |..:...:..|::..|       ::||:::.|.::..:  :|:.
  Fly   213 TPEMVKSAVH-DVEVFLKDTHLQIKQKLDNGFHVSVERVVKDLEDVDVLLGEPIQAEISAHTGLE 276

  Fly   275 --------LRIKNRLLDARRLATQFRDALRGVKRDLMVILIADCTHSECQDFYRANEIKMLDMGC 331
                    |.:.|..|..|.|..|     ..|.|.|.:...|.....|.|     .::.:|...|
  Fly   277 LAYDSLTTLSLANAELIYRVLMLQ-----ETVGRALKLSQEAAARMEELQ-----IQLSVLQRQC 331

  Fly   332 LHYDSLPEFEPLLESVQEVIDSKFIDYPLQAVGQLRRMSSAIKNRMSDILDSVNKD--------- 387
            .:.|     .||.:::                    |:.|..:|.:.|.|.::.:|
  Fly   332 TYRD-----RPLCDTL--------------------RIRSFEENGVVDALKTLQEDQSIFRMRYL 371

  Fly   388 --LNKGA--KKLQERYEASLKVLRQVVEEMKKD------MPLVVKTNPRSRSTPAAD-------- 434
              :..||  |.|......|..:.....:::|.|      ..|....:.|.|:|..|.
  Fly   372 GEIEFGATVKNLTSEVGVSRSIFSNFPQQVKHDTAYERNYTLEQLASIRHRTTANAQQLTSTVNG 436

  Fly   435 LRRKLGSSW-----------------------FGTTLCLIVLLMLVPLLLLF-------GLLIAL 469
            |.|:|..:|                       .||.:..::|.||:......       |::..
  Fly   437 LLRRLEDTWSSLQPAYNELKEWADAYWSVGWIAGTVIVWVMLFMLMSYCCFLCESNAKSGVVFF- 500

  Fly   470 FSPKVASWLLC--AVLVALFILFSVGV-----ILV---LF---YLVHGALIYQ-AFCSRKFPQP- 519
                :|..|:|  ::.:.:|.:||:.|     :.|   |:   |.:.|.|:.: .:...:.||.
  Fly   501 ----IAVMLICLASICLTIFGVFSLAVGGNAEVFVCRSLYDEDYNMLGKLLDKPGYAYAREPQTG 561

  Fly   520 VDNKSINPNKFLPENVTTFRSMPMVRTSEILQSCVRNESLYNVLGIKEIYDPYGFRDDVMIDVVK 584
            :..:.:.|       |...||:..|...:.|:.|.:|::.|||           |:.|..::..|
  Fly   562 IIGELLRP-------VGVNRSVVNVGLGQALRGCEQNQASYNV-----------FQLDAFVNTSK 608

  Fly   585 ---------------SLEKMGNTSMPGAPKEIHPDAEESAKKLLTG-------NLSTY------- 620
                           ::...|.|.:         ...:|.:.:|..       ||:||
  Fly   609 IADLRQFPKVSTAIDAISVSGRTLL---------SLTQSVQNILDNMLQTSSFNLTTYRSSVGAP 664

  Fly   621 -DIKDYTKYI---------CPQLVPEPNPGPLDGLTRKLESLANKVEPGVTLKNQAI-HLRAYQK 674
             ..||...:|         ...:........|...:::|:  |:.::|...|:|:.: ||.|.:
  Fly   665 TPEKDLATFIDQMQRVALQIQDVATSSRMTTLGSRSKRLQ--ASILQPLENLQNEILYHLTALE- 726

  Fly   675 HLCVPLAAIVQRLIKRLKQMDWLLSGGYGSFVKYLHHLLDKIKQGDDLLRQDSKKEADEVARNIS 739
                            |::..|         .|.::..|:.:|.....|    :.:|.|:..|::
  Fly   727 ----------------LQRDPW---------AKQVNQTLNHLKSIQSYL----ENKAGEICHNMT 762

  Fly   740 KLVKSGLDDYVRVVEEATKEDMES--------CEPLIREDDEAMVEYADLCNRIAKPMNAIWFWL 796
            :..:..|..|:    ..:|..|||        |.|.....|.:.   ..||..:...:|.:.|:
  Fly   763 RDYRDRLKAYL----TTSKATMESQLGDTTTKCRPFYDTFDASR---TFLCRNMVDFINGLTFF- 819

  Fly   797 LLFSSLLL-----PTICCTHFLRSRLNSLKHSVA 825
             :|.:|||     |.......:::|||.::.:.|
  Fly   820 -IFLTLLLWAIGTPVGLNLITVQTRLNVMQAAQA 852

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG45067	NP_001334707.1	Prominin	<215..791	CDD:461660	125/722 (17%)
prom	NP_001137754.1	Prominin	73..826	CDD:461660	150/851 (18%)
		PRK12678	848..>1009	CDD:237171	1/5 (20%)
		U2AF_lg	944..>1034	CDD:273727