DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht7 and Chi3l1

DIOPT Version :9

Sequence 1:	NP_647768.3	Gene:	Cht7 / 38370	FlyBaseID:	FBgn0035398	Length:	1013	Species:	Drosophila melanogaster
Sequence 2:	NP_001296749.1	Gene:	Chi3l1 / 89824	RGDID:	620874	Length:	391	Species:	Rattus norvegicus

Alignment Length:	406	Identity:	187/406 - (46%)
Similarity:	250/406 - (61%)	Gaps:	25/406 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    89 AAAAGGAAVAAGGTA---LVASGSSLKGKKTKVDDGTPKIVCYYTNWSQYRVKIGKFVPEDIPAD 150
            |.|..|..||..|.|   |:.|.|:.            |:|||||||||||...|...|:.:...
  Rat     5 AEARMGMRVALTGFAVLMLLQSCSAY------------KLVCYYTNWSQYREGNGSCFPDALDHS 57

  Fly   151 LCTHIIFAFGWLKKNKLSSYESNDETKDNVPGLYERMMTLKKANPKLKILLALGGWSFGTQKFKD 215
            ||||||::|..:..||||:.|.||.|      ||..:.|||..||:||.||::||||||:::|..
  Rat    58 LCTHIIYSFANISNNKLSTSEWNDVT------LYGMLNTLKTRNPRLKTLLSVGGWSFGSERFSR 116

  Fly   216 MSSTRYTRQTFVYSAIPFLRKRGFDGLDMDWEYPKGSDDKKNFVLLLKELREAFEAEAQELKKPR 280
            :.|...:|:|||.|..||||..||||||:.|.|| |..||::|..|:|||:..|..|.|. ...:
  Rat   117 IVSNAKSRKTFVQSVAPFLRTYGFDGLDLAWLYP-GPKDKQHFTTLIKELKAEFTKEVQP-GTEK 179

  Fly   281 LLLSAAVPVGPDNIRGGYDVPAIASYLDFINLMAYDFHGKWERETGHNAPLYAPSTDSEWRKQLS 345
            |||||||..|...:..||||..||.:|||||||.|||||.|...|||::||:....|:...:..:
  Rat   180 LLLSAAVSAGKVTLDSGYDVAQIAQHLDFINLMTYDFHGTWRHTTGHHSPLFRGQQDTGPDRFSN 244

  Fly   346 VDNAASLWVKMGAPKEKLVIGMPTYGRSFTLANPDKHGPNAPASGGGREGVYTKEGGFLAYYEIC 410
            ||......:::|||..|||:|:||:|:|||||:.:.. ..||.:|.|..|.||||.|.|||||||
  Rat   245 VDYGVGYMLRLGAPTNKLVMGIPTFGKSFTLASSENQ-VGAPITGSGLPGRYTKEKGTLAYYEIC 308

  Fly   411 EMLLNGAVYVWDDEMKVPYLVDGDQWVGFDDERAIRNKMHWIKSNGFGGAMVWTIDMDDFKGEVC 475
            :.|....|:....: :||:...|:||||:||..:::||:.::|:....|||||.:|:|||:|..|
  Rat   309 DFLRGAEVHRILGQ-QVPFATKGNQWVGYDDPESVKNKVKYLKNKQLAGAMVWAVDLDDFRGSFC 372

  Fly   476 GGNVKYPLIGAMREEL 491
            |.||.:||..|::|.|
  Rat   373 GHNVHFPLTNAIKEAL 388

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht7	NP_647768.3	Glyco_18	124..468	CDD:214753	164/343 (48%)
		GH18_chitolectin_chitotriosidase	125..491	CDD:119351	175/365 (48%)
		Glyco_18	559..898	CDD:214753
		GH18_chitolectin_chitotriosidase	560..919	CDD:119351
		CBM_14	951..1005	CDD:279884
Chi3l1	NP_001296749.1	Glyco_18	31..365	CDD:214753	164/343 (48%)
Chi3l1	NP_001296749.1	GH18_chitolectin_chitotriosidase	32..388	CDD:119351	175/365 (48%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166350386
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264489at33208
OrthoFinder	1	1.000	-	-		FOG0000107
OrthoInspector	1	1.000	-	-		mtm9066
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X91
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.850