DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht7 and chia

DIOPT Version :9

Sequence 1:	NP_647768.3	Gene:	Cht7 / 38370	FlyBaseID:	FBgn0035398	Length:	1013	Species:	Drosophila melanogaster
Sequence 2:	NP_001186489.1	Gene:	chia / 548404	XenbaseID:	XB-GENE-5868468	Length:	482	Species:	Xenopus tropicalis

Alignment Length:	473	Identity:	194/473 - (41%)
Similarity:	273/473 - (57%)	Gaps:	45/473 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   559 QVFCYLTSWSAKRPGAGKFQPENIDPKLCTHIVYAFATLQDYKLTEATDDDPENYESVIALRDNN 623
            ::.||.|:|:..|||.|||:|:||||.||||::||||.:.:.::|....:|...|.|...|::.|
Frog    23 ELTCYFTNWAQYRPGLGKFKPDNIDPCLCTHLIYAFAGMSNNQITTIEWNDVTLYSSFQNLKNQN 87

  Fly   624 PDLQILLAIGGWAFGSTPFKELTSNVFRMNQFVYEAIDFLRDYKFNGLDVDWEYP--RGA--EDR 684
            .:|:.|||||||.||:.||..:.:.......|:...|.|||.|.|:|||.|||||  ||:  :|:
Frog    88 GNLKTLLAIGGWNFGTAPFTAMVATAQSRQTFISSVIKFLRQYGFDGLDFDWEYPGSRGSPPQDK 152

  Fly   685 VAYVSLLKELRVAFEGEAKSSGLPRLLLTAAVPASFEAIAAGYDVPEISKYLDFINVMTYDFHGQ 749
            ..:.:|::|:..|||.||..|..|||::||||.|....|.:||.:|::|:.||:|:|||||.||.
Frog   153 QLFTTLVQEMLAAFEAEASQSNKPRLMVTAAVAAGISNIESGYQIPQLSQALDYIHVMTYDLHGS 217

  Fly   750 WERTVGHNSPLFALESATGYQKKLTVDYSAREWVKQGAPKEKLLIGMPTYGRSFELVNDTQFDIG 814
            ||...|.||||:...|||||...|.|||....|:..|||..||::|.||||.:|.|.|.:...||
Frog   218 WEGYTGENSPLYTNPSATGYNAYLNVDYVMNYWLNNGAPASKLIVGFPTYGHTFILSNPSNNGIG 282

  Fly   815 SPSSGGGKAGKFTNEAGFLSYYEVCSFLAADNTTLVWDSEQQVPFAYRGNQWVGFDDERSLKTKT 879
            :|:||.|.||.:|.:|||.:|||:|:|| .:..|.:|.|.:.||:||:|::|:|:|:|:|.:.|.
Frog   283 APTSGNGPAGPYTRQAGFWAYYEICTFL-KNGATNLWSSAEDVPYAYQGSEWLGYDNEKSFQIKA 346

  Fly   880 EWLKEQGFGGIMVWSIDMDDFSGR-CGSGKYPLLTALNDELKDYKVELEYDG---PYESHGPRGA 940
            |||.:...||.|||:||:|||:|. |..||:||:..|.:.|     .::..|   |.....|
Frog   347 EWLMKNNLGGAMVWAIDLDDFTGTFCNQGKFPLINTLKNTL-----GVQASGCTPPATPVAP--- 403

  Fly   941 YTTKDPHDVT-----------------------CAEEDGHISYHKDWADCTH-YYMCEGERKHHM 981
             .|..|..|.                       ||   |..|.....|..|: ::.|.....:..
Frog   404 -VTAAPATVPSGSGSGSSGSGSSSGGSSGGSGFCA---GKASGLYPVAGNTNAFWHCLNGITYQQ 464

  Fly   982 PCPANLVFNPQENVCDWP 999
            .|...|||:|....|:||
Frog   465 HCQTGLVFDPSCECCNWP 482

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht7	NP_647768.3	Glyco_18	124..468	CDD:214753
		GH18_chitolectin_chitotriosidase	125..491	CDD:119351
		Glyco_18	559..898	CDD:214753	162/342 (47%)
		GH18_chitolectin_chitotriosidase	560..919	CDD:119351	172/363 (47%)
		CBM_14	951..1005	CDD:279884	15/50 (30%)
chia	NP_001186489.1	GH18_chitolectin_chitotriosidase	24..387	CDD:119351	172/363 (47%)
		Glyco_18	26..365	CDD:214753	162/339 (48%)
		CBM_14	436..482	CDD:279884	13/48 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264489at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2066
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.040