Protein Alignment Cht7 and LOC4578142

DIOPT Version :10

• Sequence 1: NP_647768.3
• Gene: Cht7 / 38370
• FlyBaseID: FBgn0035398
• Length: 1013
• Species: Drosophila melanogaster
• Sequence 2: XP_001238192.3
• Gene: LOC4578142 / 4578142
• VectorBaseID: AGAMI1_000982
• Length: 2401
• Species: Anopheles gambiae
• Alignment Length: 1019
• Identity: 360/1019 - (35%)
• Similarity: 532/1019 - (52%)
• Gaps: 173/1019 - (16%)

  Fly   115 KTKVDDGTP-----------KIVCYYTNWSQYRVKIGKFVPEDIPADLCTHIIFAFGWLKKNKLS 168
            :|.|...||           |:|||:|||:.||...||:.|:.|..||||||::.|..|..:.|
Mosquito   990 RTTVAPSTPPPVLEPLSGHYKMVCYFTNWAWYRKGYGKYTPDHIRTDLCTHIVYGFAVLDYSTL- 1053

  Fly   169 SYESNDETKDNVPGLYERMMTLKKANPKLKILLALGGWSFGT-QKFKDMSSTRYTRQTFVYSAIP 232
            :.:::|...|.....|.|::..|:..  :|:.||:|||:... .|:..:..:...|..||...:.
Mosquito  1054 TIKTHDSWADIDNKFYARVVAAKEKG--VKVTLAIGGWNDSAGDKYSRLVRSAAARSKFVQHVVG 1116

  Fly   233 FLRKRGFDGLDMDWEYP--------KG-SDDKKNFVLLLKELREAFEAEAQELKKPR-LLLSAAV 287
            ||.|.||:|||:|||||        || :|:|:.|..|::||.|||        :|| .||||||
Mosquito  1117 FLEKYGFEGLDLDWEYPVCWQVDCKKGYADEKEGFTELVRELSEAF--------RPRDWLLSAAV 1173

  Fly   288 PVGPDNIRGGYDVPAIASYLDFINLMAYDFHGKWERETGHNAPL-YAPSTDSEWRKQLSVDNAAS 351
            ......|..||||.|:|.|.|:|.:|.|||||:|:::|||.||| |.|..:.::   .:.:.:.:
Mosquito  1174 SPSKTVIDAGYDVAALAQYFDWIAVMTYDFHGQWDKQTGHVAPLYYHPDDEIDF---FNANYSIN 1235

  Fly   352 LWVKMGAPKEKLVIGMPTYGRSFTLANPDKHGPNAPASGGGREGVYTKEGGFLAYYEICEMLLN- 415
            .|::.|||..|||:|||.||:||.||:..|:|.||.|.|.|:.|.:|:..|||||||||:.:.|
Mosquito  1236 YWIEKGAPPRKLVMGMPLYGQSFQLADTKKNGLNAKAPGPGQAGEFTRAAGFLAYYEICDRIQNK 1300

  Fly   416 GAVYVWDDEMKV-PYLVDGDQWVGFDDERAIRNKMHWIKSNGFGGAMVWTIDMDDFKGEVCGGNV 479
            |...|.||..:: ||...|:|||.|||:.::..|:.:|::...||.|:|.:|:|||| :.||..
Mosquito  1301 GWTVVQDDLQRMGPYAYKGNQWVSFDDKESLLRKVQFIRAMDLGGGMIWALDLDDFK-DRCGQG- 1363

  Fly   480 KYPLIGAMREELLGISRGKEAKDVNWTAVAATFEDIEEKPEPIKISVDE-ILNKVRKPQVQKKQR 543
            .:||:.|:||   |:.....:.||..|.|.....:     |.:.:|.:. ..|....|  :|:|.
Mosquito  1364 SHPLLTAIRE---GLREPYNSNDVLPTIVKEPMAN-----ENLALSTESPSTNSNSSP--EKQQP 1418

  Fly   544 IKSGANAVASNTRPA---QVFCYLTSWSAKRPGAGKFQPENIDPKLCTHIVYAFATLQDYKLTEA 605
            ..:.:..|..|:..:   :|.||.|:|:..|.|.||:.||:|||.|||||||.||.|....||..
Mosquito  1419 ASNESTEVDENSVDSDEYKVVCYFTNWAWYRQGNGKYLPEDIDPDLCTHIVYGFAVLDREGLTIK 1483

  Fly   606 TDD---DPEN--YESVIALRDNNPDLQILLAIGGW-AFGSTPFKELTSNVFRMNQFVYEAIDFLR 664
            ..|   |.:|  ||.|:.|:....  ::.:||||| ......:..|..:.....:|:...:.|:.
Mosquito  1484 PHDSWADIDNRFYERVVELKKKGK--KVTVAIGGWNDSAGDKYSRLVRSAQARKRFIDNVMQFIE 1546

  Fly   665 DYKFNGLDVDWEYP--------RG-AEDRVAYVSLLKELRVAFEGEAKSSGLPRLLLTAAVPASF 720
            .|.|:|||:|||||        :| |:::..:.||:.||..||    |..|   .||::||..|.
Mosquito  1547 KYGFDGLDLDWEYPVCWQVDCKKGYADEKEGFASLVVELATAF----KPYG---YLLSSAVSPSK 1604

  Fly   721 EAIAAGYDVPEISKYLDFINVMTYDFHGQWERTVGHNSPLFAL--ESATGYQKKLTVDYSAREWV 783
            :.|.|||||..:|.|:|:|.|||||:||||::..||.:|::..  :..|.:....|:.|    |:
Mosquito  1605 KVIDAGYDVRTLSDYMDWIAVMTYDYHGQWDKQTGHVAPMYEHPDDVDTTFNANFTIHY----WI 1665

  Fly   784 KQGAPKEKLLIGMPTYGRSFELVNDTQFDIGSPSSGGGKAGKFTNEAGFLSYYEVCSFLAADNTT 848
            :|||...||::|||.||:||.|.|.....:...:.|||:||..|...|||||||:||.:...|..
Mosquito  1666 EQGADPRKLVMGMPMYGQSFSLANVNANGLNEKTYGGGEAGDQTRARGFLSYYEICSNINKKNWN 1730

  Fly   849 LVWDSEQQV-PFAYRGNQWVGFDDERSLKTKTEWLKEQGFGGIMVWSIDMDDFSGRCGSGKYPLL 912
            :|.|.:.:: |:||:|:|||.|||:..::.|:|::|..|.||.|:|::|:|||...||..:||||
Mosquito  1731 VVRDRKGRMGPYAYKGDQWVSFDDQYMIRHKSEYVKAMGLGGAMIWALDLDDFRNICGCEEYPLL 1795

  Fly   913 TALNDELKDYKVELEYDGPYESHGPR-------------------------------------GA 940
            ..:|..|::      |.||    ||:                                     .|
Mosquito  1796 RTINRVLRN------YPGP----GPKCILGSTKPSPDRPTTAMTTTTTRSTTRRPTTTVRTTTTA 1850

  Fly   941 YTTKDPHDVTCAEE--------------------------------DGHISYHKDWADCTHYYMC 973
            .|:..|..|:...:                                ||.:....: :||:.||:|
Mosquito  1851 TTSTTPRAVSTTRQTTRRTTTRFSTTSRPTTPSIDDLDSNQSSSKCDGRLFIPHE-SDCSKYYIC 1914

  Fly   974 EGERKHHMPCPANLVFNPQENVCDWPENVEGCHTP----TEAPA 1013
            :..:::...||.|..:|  ...|||.||. .|...    |.||:
Mosquito  1915 QHGKRYEQRCPTNTAWN--NGYCDWEENT-NCKNKQGPVTSAPS 1955

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cht7	NP_647768.3	GH18_chitolectin_chitotriosidase	125..491	CDD:119351	159/379 (42%)
		GH18_chitolectin_chitotriosidase	560..919	CDD:119351	153/376 (41%)
		CBM_14	951..1005	CDD:426342	16/85 (19%)
LOC4578142	XP_001238192.3	None