DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht7 and chia.1

DIOPT Version :9

Sequence 1:	NP_647768.3	Gene:	Cht7 / 38370	FlyBaseID:	FBgn0035398	Length:	1013	Species:	Drosophila melanogaster
Sequence 2:	NP_998215.1	Gene:	chia.1 / 406323	ZFINID:	ZDB-GENE-040426-1994	Length:	455	Species:	Danio rerio

Alignment Length:	457	Identity:	172/457 - (37%)
Similarity:	258/457 - (56%)	Gaps:	27/457 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   551 VASNTRPAQVFCYLTSWSAKRPGAGKFQPENIDPKLCTHIVYAFATLQ-DYKLTEATDDDPENYE 614
            :.|:|:   :.||:|:||..|||.|||.||||||.||||:|||.||:. |.::|....:|.:.|:
Zfish    18 IVSSTK---LVCYMTNWSQYRPGNGKFLPENIDPFLCTHVVYALATISYDNQITTIEWNDVDLYK 79

  Fly   615 SVIALRDNNPDLQILLAIGGWAFGSTPFKELTSNVFRMNQFVYEAIDFLRDYKFNGLDVDWEYP- 678
            |:..|:..||.|:..|::||...|.:|:..:.:.......|:..|:.|||.::|:|:|:||:||
Zfish    80 SMNELKKVNPALKTQLSVGGLVNGVSPYINMVATPENRKAFIRNALLFLRLHEFDGMDIDWQYPG 144

  Fly   679 -RGA--EDRVAYVSLLKELRVAFEGEAKSSGLPRLLLTAAVPASFEAIAAGYDVPEISKYLDFIN 740
             .|:  :|:....:.:||:|.|.|.||..:....|||:..|.|....|...|:..|::..:||:.
Zfish   145 HNGSPPQDKQRLTTFIKEMRDAIEQEAIDTKKTPLLLSIKVSAIKTTIENAYEAKEVASLVDFVT 209

  Fly   741 VMTYDFHGQWERTVGHNSPLFALESATGYQKKLTVDYSAREWVKQGAPKEKLLIGMPTYGRSFEL 805
            :|:||:||.|:...|||||||.....||......::.|...|:..|||.::||:|:|||||:| :
Zfish   210 IMSYDYHGHWDPITGHNSPLFRSSFDTGSIVHHNINSSLEFWLGSGAPADRLLLGLPTYGRTF-M 273

  Fly   806 VNDTQFDIGSPSSGGGKAGKFTNEAGFLSYYEVCSFLAADNTTLVWDSEQQVPFAYRGNQWVGFD 870
            ::.:|..:|:|::|...||.:|.||||.||||:|..  ..:..:.|..||.||:|.:|..|||||
Zfish   274 LSTSQTGLGAPANGPADAGPYTREAGFWSYYEICPM--ESSVPIHWIDEQMVPYAVQGRAWVGFD 336

  Fly   871 DERSLKTKTEWLKEQGFGGIMVWSIDMDDFSGR-CGSGKYPLLTALNDELKDYKVELEYDG--PY 932
            ::.|:..|.:||.....||..||::|.|||:|| |.:|.|||:..|.:.|          |  |.
Zfish   337 NQESITAKVQWLNSLKLGGASVWTLDFDDFAGRFCYNGAYPLVNHLRNSL----------GFPPK 391

  Fly   933 ESHGPRGAYTTKDPHDVTCAEEDGHISYHKDWADCTHYYMCEGERKHHMPCPANLVFNPQENVCD 997
            .:..||.. ||.||.:..|..:...:..|.  .|.:.|:.|.....:...|...|||......||
Zfish   392 PTTTPRPT-TTADPINSFCVGKPDGLYPHP--TDASKYFHCFRGNTYLQQCQPGLVFVDACKCCD 453

  Fly   998 WP 999
            ||
Zfish   454 WP 455

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht7	NP_647768.3	Glyco_18	124..468	CDD:214753
		GH18_chitolectin_chitotriosidase	125..491	CDD:119351
		Glyco_18	559..898	CDD:214753	137/343 (40%)
		GH18_chitolectin_chitotriosidase	560..919	CDD:119351	148/364 (41%)
		CBM_14	951..1005	CDD:279884	13/49 (27%)
chia.1	NP_998215.1	Glyco_18	23..364	CDD:214753	137/346 (40%)
		GH18_chitolectin_chitotriosidase	24..386	CDD:119351	148/364 (41%)
		ChtBD2	407..455	CDD:214696	11/49 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592098
Domainoid	1	1.000	352	1.000	Domainoid score	I965
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264489at33208
OrthoFinder	1	1.000	-	-		FOG0000107
OrthoInspector	1	1.000	-	-		mtm6443
orthoMCL	1	0.900	-	-		OOG6_100224
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X91
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.750