DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht7 and Idgf4

DIOPT Version :9

Sequence 1:	NP_647768.3	Gene:	Cht7 / 38370	FlyBaseID:	FBgn0035398	Length:	1013	Species:	Drosophila melanogaster
Sequence 2:	NP_001285068.1	Gene:	Idgf4 / 31926	FlyBaseID:	FBgn0026415	Length:	442	Species:	Drosophila melanogaster

Alignment Length:	442	Identity:	127/442 - (28%)
Similarity:	197/442 - (44%)	Gaps:	93/442 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   121 GTPKIVCYYTNWSQYRVKIGKFVPEDI-PA-DLCTHIIFAFGWL--KKNKLSSYESNDETKDNVP 181
            |:..::|||...|..|..:.|.:..|: || ..|||:::.:..:  ..|||   .||:|..|...
  Fly    23 GSHHLLCYYDGNSFVREGLSKLILTDLEPALQYCTHLVYGYAGINPSSNKL---VSNNEKLDLDL 84

  Fly   182 G--LYERMMTLKKANPKLKILLALGGWSFGTQKFKDMSSTRY--------TRQTFVYSAIPFLRK 236
            |  |:.::..||:..|.||:||::|    |.:...|..:.:|        .|..|:.||...::.
  Fly    85 GSSLFRQVTGLKRKYPALKVLLSVG----GDKDTVDPENNKYLTLLESSNARIPFINSAHSLVKT 145

  Fly   237 RGFDGLDMDWEYPKGSDDK---------KNFVLLL----------KELREAFEAEAQELK---KP 279
            .||||||:.|::||....|         |.|..:.          :|.:|||.|..:|||   :|
  Fly   146 YGFDGLDLGWQFPKNKPKKVHGSIGKFWKGFKKIFSGDHVVDEKAEEHKEAFTALVRELKNAFRP 210

  Fly   280 --RLLLSAAVPVGPDNIRGG--YDVPAIASYLDFINLMAYDFHGKWERE---TGHNAPLYAPSTD 337
              .:|..:.:|    |:...  :|||||.:.||::||..|||... ||.   ....||:|..
  Fly   211 DGYILGLSVLP----NVNSSLFFDVPAIINNLDYVNLHTYDFQTP-ERNNEVADFPAPIYEL--- 267

  Fly   338 SEWRKQLSVDNAASLWVKMGAPKEKLVIGMPTYGRSFTLANPDKHG-----PNAPASGGGREGVY 397
            :|...:.:|:.....|....||..|:.:|:.||||::.|....  |     |.|.|.|....|..
  Fly   268 NERNPEFNVNYQVKYWTGNRAPAAKINVGIATYGRAWKLTKDS--GLTGLPPVAEADGVAPAGTQ 330

  Fly   398 TKEGGFLAYYEICEMLLNGAVYVWDDEMK---VPYLVDGDQ--------------------WVGF 439
            |:..|.|::.|:|..|.|.|    :..:|   .|....||.                    |||:
  Fly   331 TQIPGLLSWPEVCAKLPNPA----NQHLKGADGPLRKVGDPTKRFGSYAYRSADDSGENGVWVGY 391

  Fly   440 DDERAIRNKMHWIKSNGFGGAMVWTIDMDDFKGEVCGGNVKYPLIGAMREEL 491
            :|......|..::|..|.||..|..:..|||:|. |.|:.|:|::..::.:|
  Fly   392 EDPDTAAIKAEYVKREGLGGIAVVDLSFDDFRGG-CTGHDKFPILRQVKSKL 442

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht7	NP_647768.3	Glyco_18	124..468	CDD:214753	117/414 (28%)
		GH18_chitolectin_chitotriosidase	125..491	CDD:119351	125/436 (29%)
		Glyco_18	559..898	CDD:214753
		GH18_chitolectin_chitotriosidase	560..919	CDD:119351
		CBM_14	951..1005	CDD:279884
Idgf4	NP_001285068.1	GH18_IDGF	26..442	CDD:119352	125/437 (29%)
Idgf4	NP_001285068.1	Glyco_18	27..420	CDD:214753	117/413 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463840
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11177
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X91
	5	4.840