DRSC/TRiP Functional Genomics Resources

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Protein Alignment Cht7 and CHIA

DIOPT Version :9

Sequence 1:NP_647768.3 Gene:Cht7 / 38370 FlyBaseID:FBgn0035398 Length:1013 Species:Drosophila melanogaster
Sequence 2:NP_970615.2 Gene:CHIA / 27159 HGNCID:17432 Length:476 Species:Homo sapiens


Alignment Length:400 Identity:189/400 - (47%)
Similarity:253/400 - (63%) Gaps:18/400 - (4%)


- Green bases have known domain annotations that are detailed below.


  Fly   124 KIVCYYTNWSQYRVKIGKFVPEDIPADLCTHIIFAFGWLKKNKLSSYESNDETKDNVPGLYERMM 188
            ::.||:|||:|||..:|:|:|::|...||||:|:||...:.|::::.|.||.|      ||:...
Human    23 QLTCYFTNWAQYRPGLGRFMPDNIDPCLCTHLIYAFAGRQNNEITTIEWNDVT------LYQAFN 81

  Fly   189 TLKKANPKLKILLALGGWSFGTQKFKDMSSTRYTRQTFVYSAIPFLRKRGFDGLDMDWEYP--KG 251
            .||..|.:||.|||:|||:|||..|..|.||...||||:.|.|.|||:..|||||.|||||  :|
Human    82 GLKNKNSQLKTLLAIGGWNFGTAPFTAMVSTPENRQTFITSVIKFLRQYEFDGLDFDWEYPGSRG 146

  Fly   252 S--DDKKNFVLLLKELREAFEAEAQELKKPRLLLSAAVPVGPDNIRGGYDVPAIASYLDFINLMA 314
            |  .||..|.:|::|:|||||.||:::.||||:::|||..|..||:.||::|.::.|||:|::|.
Human   147 SPPQDKHLFTVLVQEMREAFEQEAKQINKPRLMVTAAVAAGISNIQSGYEIPQLSQYLDYIHVMT 211

  Fly   315 YDFHGKWERETGHNAPLYAPSTDSEWRKQLSVDNAASLWVKMGAPKEKLVIGMPTYGRSFTLANP 379
            ||.||.||..||.|:|||...||:.....|:||...:.|...|||.|||::|.||||.:|.|:||
Human   212 YDLHGSWEGYTGENSPLYKYPTDTGSNAYLNVDYVMNYWKDNGAPAEKLIVGFPTYGHNFILSNP 276

  Fly   380 DKHGPNAPASGGGREGVYTKEGGFLAYYEICEMLLNGAVYVWDDEMKVPYLVDGDQWVGFDDERA 444
            ...|..||.||.|..|.|.||.|..||||||..|.|||...||...:|||...|:.|||:|:.::
Human   277 SNTGIGAPTSGAGPAGPYAKESGIWAYYEICTFLKNGATQGWDAPQEVPYAYQGNVWVGYDNIKS 341

  Fly   445 IRNKMHWIKSNGFGGAMVWTIDMDDFKGEVCGGNVKYPLIGAMREELLGISRGKEAKDVNWTAVA 509
            ...|..|:|.|.|||||||.||:|||.|..|... |:|||..:: :.||:      :..:.||.|
Human   342 FDIKAQWLKHNKFGGAMVWAIDLDDFTGTFCNQG-KFPLISTLK-KALGL------QSASCTAPA 398

  Fly   510 ATFEDIEEKP 519
            ...|.|...|
Human   399 QPIEPITAAP 408

Known Domains:


Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.

GeneSequenceDomainRegion External IDIdentity
Cht7NP_647768.3 Glyco_18 124..468 CDD:214753 172/347 (50%)
GH18_chitolectin_chitotriosidase 125..491 CDD:119351 181/369 (49%)
Glyco_18 559..898 CDD:214753
GH18_chitolectin_chitotriosidase 560..919 CDD:119351
CBM_14 951..1005 CDD:279884
CHIANP_970615.2 GH18_chitolectin_chitotriosidase 24..387 CDD:119351 181/370 (49%)
Glyco_18 26..365 CDD:214753 172/344 (50%)