DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht7 and cht-4

DIOPT Version :9

Sequence 1:	NP_647768.3	Gene:	Cht7 / 38370	FlyBaseID:	FBgn0035398	Length:	1013	Species:	Drosophila melanogaster
Sequence 2:	NP_497437.2	Gene:	cht-4 / 189507	WormBaseID:	WBGene00021252	Length:	360	Species:	Caenorhabditis elegans

Alignment Length:	379	Identity:	110/379 - (29%)
Similarity:	178/379 - (46%)	Gaps:	65/379 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   560 VFCYLTSWSAKRPGAGKFQPENIDPKLCTHIVY--AFATLQDYKLTEATDDDPENY--------E 614
            |.||   :...:|...|. |:|    |||||:.  :....:|.:| :..:.|.|::        |
Worm    20 VACY---YILNQPDISKV-PKN----LCTHIILINSAHVSEDGRL-QGFEQDLEHFSELFDGKIE 75

  Fly   615 SVIALRDNNPDLQILLAIGGWAFGSTPFKELTSNVFRMNQFVYEAIDFLRDYKFNGLDVDWEYP- 678
            ..:::..:||.                |..||||...|:.|.......|:.|:.||:|:|||:|
Worm    76 LFVSITSSNPS----------------FSFLTSNTTLMHNFSSTVTQVLQKYRLNGVDIDWEFPV 124

  Fly   679 --RGAE--DRVAYVSLLKELRVAFEGEAKSSGLPR-LLLTAAVPASFEAIAAGYDVPEISKYLDF 738
              |.|:  |:..:.:.|:.|        ||...|. |.|:.||..........|||..:..|.|.
Worm   125 WSRDAQKSDKAHFATFLRIL--------KSHLKPADLKLSVAVSGPPTISRKAYDVDALKMYADM 181

  Fly   739 INVMTYDFH--GQWERT-VGHNSPLFALESATGYQKKLTVDYSAREWVKQGAPKEKLLIGMPTYG 800
            :.:|.||||  .::... ||.|:||..:.:......::..:.|.:.|...|.|:.....|:|||.
Worm   182 VQIMNYDFHVFNRYSNPFVGFNAPLHPMRAEISVLGEMNAEASMKTWYDLGLPRNISFFGIPTYA 246

  Fly   801 RSFELVNDTQFDIGSPSSGGGKA-GKFTNEAGFLSYYEVCSFLAADNTTLVWDSEQQVPFAYRGN 864
            |:|:|:  |.: :..|.|...:| .:.||      ..:||.|..:...|.||:...|.|:.| |:
Worm   247 RAFQLL--THY-LHKPYSPAIRARPEITN------LPDVCIFAQSGYYTTVWNHHAQAPYLY-GD 301

  Fly   865 Q--WVGFDDERSLKTKTEWLKEQGFGGIMVWSIDMDDFSGRCGSGKYPLLTALN 916
            .  ||.:::::|:..|..:.::...||:||:||..||.:|:||.|.|||||.::
Worm   302 DGIWVSYENQQSILAKMAFARKLQVGGVMVFSIGSDDVTGKCGHGPYPLLTKIS 355

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht7	NP_647768.3	Glyco_18	124..468	CDD:214753
		GH18_chitolectin_chitotriosidase	125..491	CDD:119351
		Glyco_18	559..898	CDD:214753	99/359 (28%)
		GH18_chitolectin_chitotriosidase	560..919	CDD:119351	110/379 (29%)
		CBM_14	951..1005	CDD:279884
cht-4	NP_497437.2	GH18_chitinase-like	30..357	CDD:385673	106/366 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S2365
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264489at33208
OrthoFinder	1	1.000	-	-		FOG0000107
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR11177
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.870