DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht7 and chil-25

DIOPT Version :9

Sequence 1:	NP_647768.3	Gene:	Cht7 / 38370	FlyBaseID:	FBgn0035398	Length:	1013	Species:	Drosophila melanogaster
Sequence 2:	NP_001300596.1	Gene:	chil-25 / 188614	WormBaseID:	WBGene00011846	Length:	483	Species:	Caenorhabditis elegans

Alignment Length:	427	Identity:	103/427 - (24%)
Similarity:	178/427 - (41%)	Gaps:	109/427 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   114 KKTKVDDGTPKI-------------VCYYTNWSQYRVKIGKFVPEDIPADLCTHIIFAFGWLKKN 165
            ||::.....|||             |.||:     |.:..|..  .:.....||.:|||.::..:
Worm    87 KKSRTSTIQPKIDPTSTVSNCNKRVVGYYS-----RSETSKIT--SVQVSKLTHAVFAFVYMNSD 144

  Fly   166 KLSSYESNDETKDNVPGLYERMMTLK----KANPKLKILLALGGWSFGTQKFKDMSSTRYTRQTF 226
            ....:|..||.        :|.|.||    .....:||::::|| ...:|.|..:..:.|.||.|
Worm   145 GTLKFEKQDEE--------DRFMQLKDIVNMGTSPVKIMISIGG-KENSQNFSPVIESEYRRQIF 200

  Fly   227 VYSAIPFLRKRGFDGLDMDWEYPKGSDDKKNFVLLLKELREAFEAEAQELKKPRLLLSAAVPVGP 291
            :.|.:.||::...||:|:.||:| .|..|..::..:.||::..:.:.::     .:||..||  |
Worm   201 INSILTFLKENDLDGIDLFWEWP-CSTYKSVYLHFICELKQQLQTKDKD-----YILSIVVP--P 257

  Fly   292 DNIRG---GYDVPAIASYLDFINLMAYDFHGKWERE----TGHNAPLY--APSTDSEWRKQLSVD 347
            ..:.|   |:|:..|...:||||:.:.|::|..:.:    ||..||::  .|.     |:..:||
Worm   258 PEVGGWIDGFDMNNIVQIVDFINVFSLDYYGPTQNDFGKITGPTAPMFNGVPG-----RETFNVD 317

  Fly   348 NAA---------------------SLWVKMGAPKEKLVIGMPTYGRSFTLANPDK-HGPNAPASG 390
            :.:                     :||..:..|.:|:.|          ..|.:| ||.....|.
Worm   318 HTSKVLSCETMQSNKFNIAIPFYTTLWENVQGPIDKIEI----------FRNVNKVHGKIVGQSH 372

  Fly   391 GGREGVYTKEGGFLAYYEICEMLLNGAVYVWDDEMKVPYLVDGDQWVGFDDERAIRNKMHWIKSN 455
            ..|. :..::|..|..|.......|  .::::...|: ||.       |:.:::|..|:.::..:
Worm   373 MSRM-IVQQKGFVLTPYSFDNATRN--AFIYNSSTKI-YLT-------FETDQSIVAKIEYVSEH 426

  Fly   456 GFGGAMVWTIDMDD----------FKGEVCGGNV-KY 481
            ..||..:||:|.||          |.|....||| ||
Worm   427 LLGGICIWTVDKDDEGNSQLNAISFDGLCTTGNVPKY 463

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht7	NP_647768.3	Glyco_18	124..468	CDD:214753	91/391 (23%)
		GH18_chitolectin_chitotriosidase	125..491	CDD:119351	99/416 (24%)
		Glyco_18	559..898	CDD:214753
		GH18_chitolectin_chitotriosidase	560..919	CDD:119351
		CBM_14	951..1005	CDD:279884
chil-25	NP_001300596.1	Glyco_18	110..439	CDD:214753	89/378 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D826687at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm14141
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820