DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht7 and chil-12

DIOPT Version :9

Sequence 1:	NP_647768.3	Gene:	Cht7 / 38370	FlyBaseID:	FBgn0035398	Length:	1013	Species:	Drosophila melanogaster
Sequence 2:	NP_506770.2	Gene:	chil-12 / 187357	WormBaseID:	WBGene00010799	Length:	450	Species:	Caenorhabditis elegans

Alignment Length:	393	Identity:	99/393 - (25%)
Similarity:	166/393 - (42%)	Gaps:	78/393 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   109 SSLKGK----KTKVDDGTPKIVCYYTNWSQYRVKIGKFVPEDIPADLCTHIIFAFGWLK------ 163
            :|.|.|    ||:.:..:.:|:.||:..|...:.|.:       ....||.||||..|.
Worm    75 NSFKNKFPPIKTEENTCSKRIIGYYSGTSDSEITINQ-------VSKLTHAIFAFVQLTFDGTLV 132

  Fly   164 -KNKLSSYESNDETKDNVPGLYERMMTL----KKANPKLKILLALGGWSFGTQKFKDMSSTRYTR 223
             :||                  .|.|.|    |..|..:|.:.::||... :|.|..:...:..:
Worm   133 FRNK------------------NRFMALRNIAKTENSTVKFMFSIGGPGH-SQNFSPVVRNQEKK 178

  Fly   224 QTFVYSAIPFLRKRGFDGLDMDWEYPKGSDDKKNFVLLLKELREAFEAEAQELKKPR--LLLSAA 286
            :.|:.|...||.:...||:|:.|::|..:|         |.....|..|..|:.|.|  .:||..
Worm   179 RRFIKSIFSFLEEHKLDGVDIFWKWPHLAD---------KHAYSQFLLELNEILKTRKDYILSIL 234

  Fly   287 VPVGPDNIRGGYDVPAIASYLDFINLMAYDFHGKWE----RETGHNAPLYAPSTDSEWRKQLSVD 347
            ||........|:.:..|...:||||:.|.|::|.|.    ..||..:|:|.   .||.|:|.:||
Worm   235 VPPQGIGFASGFKMNEIVENVDFINIFAMDYYGPWASGWGNPTGPISPIYG---GSERREQWNVD 296

  Fly   348 NAASLWVKMGAPKEKLVIGMPTYGRSFTLANPDKHGPNAPASGGGREGVYT-------KEGG--F 403
            |.|:::........|..|.:|.:.|.:.  |..|     |....|:| ||.       |..|  :
Worm   297 NTAAIYSCETMRSSKFNIVIPFFARLWN--NVGK-----PIDFPGKE-VYRNVTLIDGKAVGEVY 353

  Fly   404 LAYYEICEMLLNGAVYVWDDEMKVPYLVDG--DQWVGFDDERAIRNKMHWIKSNGFGGAMVWTID 466
            :......:...|.:.|.:||..:..::.:.  .:::.|:.:|:|..|:.::::...||..:|.:|
Worm   354 MPRRSALQKGYNLSSYNYDDLSETAFIYNSTTKEYLTFEVKRSIAAKLDYVQNMNLGGVWIWQMD 418

  Fly   467 MDD 469
            |||
Worm   419 MDD 421

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht7	NP_647768.3	Glyco_18	124..468	CDD:214753	91/371 (25%)
		GH18_chitolectin_chitotriosidase	125..491	CDD:119351	94/373 (25%)
		Glyco_18	559..898	CDD:214753
		GH18_chitolectin_chitotriosidase	560..919	CDD:119351
		CBM_14	951..1005	CDD:279884
chil-12	NP_506770.2	Glyco_18	94..420	CDD:214753	91/371 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D826687at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm14141
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820