DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht7 and chil-6

DIOPT Version :9

Sequence 1:	NP_647768.3	Gene:	Cht7 / 38370	FlyBaseID:	FBgn0035398	Length:	1013	Species:	Drosophila melanogaster
Sequence 2:	NP_496126.1	Gene:	chil-6 / 182436	WormBaseID:	WBGene00007471	Length:	460	Species:	Caenorhabditis elegans

Alignment Length:	506	Identity:	104/506 - (20%)
Similarity:	210/506 - (41%)	Gaps:	110/506 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LLRIAFVICLLIVLLSPSADSAQTKTRRRLRRPTTSVSSSRSNLIESKKSTEAPEAEKRIDQITS 70
            |:....::..::|:.:|.|.|. ::.....|..:.:||:..:.||.|.:::.           |:
Worm    32 LINPCLILIAILVISAPVAFSL-SELIMVARHKSETVSNLINMLIPSSQTSR-----------TT 84

  Fly    71 ATTTSARRTRL--RSKAKLGAAAAGGAAVAAGGTALVASGSSLKGKKTKVDDGTPKIVCYYTNWS 133
            ..|.::..|:|  :|..|:...||.                  .||         :||.|:..:
Worm    85 MKTNNSPTTKLVQKSNEKVSPPAAS------------------CGK---------RIVGYFAEF- 121

  Fly   134 QYRVKIGKFVPEDIP-----ADLCTHIIFAFGWLKKNKLSSYESNDETKDNVPGLYERMMT-LKK 192
                       |:.|     ..:.||||:.|...|...|:..:.:...|      :..|.. .:|
Worm   122 -----------ENSPLSKKQLQMLTHIIYLFAIPKNGSLTFRDESSRRK------FVAMKNEARK 169

  Fly   193 ANPKLKILLALGGWSFGTQKFKDMSSTRYTRQTFVYSAIPFLRKRGFDGLDMDWEYPKGSDDKKN 257
            .:..||:::::|| .:.:.:|..:.|...:|..|..|.:.|::....||:|:.|.:||.||: .|
Worm   170 ESSTLKVMISIGG-QYSSGEFSGLVSKETSRNLFTNSIVSFVQNYDIDGVDIFWTWPKYSDE-NN 232

  Fly   258 FVLLLKELREAF-EAEAQELKKPRLLLSAAVPVGPDNIRGGYDVPAIASYLDFINLMAYDFHGKW 321
            :::.::|||.|| |.:.:..:|...::|..:   ..|:....::...::::||:|:..::   .:
Worm   233 YLMFIRELRYAFTELQKKLNRKETFVISLVI---SRNVNHLSNLVEFSNFVDFLNIYLFN---SF 291

  Fly   322 ERETGHNAPLYAPSTDSEWRKQLSVDNAASLWVKMGAP-KEKLVIGM-PTYGRSFTLANPDKHGP 384
            ..:.|.::|||...:      ::..:|......|.|.| |..:::.. .||.....|...|....
Worm   292 LNQIGPDSPLYGGGS------RIVDENMKYYICKSGQPSKFNIIVSFHATYWNGAELPLRDDSDD 350

  Fly   385 NAPASGGGREGVYTKEGGFLAY-YEICEML---LNGAVYVWDDEMKVPYLVDG--DQWVGFDDER 443
            ....:..||..:.........| :.:.::.   |....|:|         :.|  .:::..::||
Worm   351 IWKDNNSGRLPIALPRRQLRQYNWNLTDIKFHNLTKTSYIW---------IPGPPTRFMTLEEER 406

  Fly   444 AIRNKMHWIKSNGFGGAMVWTIDMDD---------FKGEVCGGN----VKY 481
            ::|.|..::..:..||..:||||.||         ...|:|.|:    :||
Worm   407 SLREKNRYVADHNIGGITMWTIDQDDDDHTLLKVVSSAELCTGDEKNTIKY 457

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht7	NP_647768.3	Glyco_18	124..468	CDD:214753	76/358 (21%)
		GH18_chitolectin_chitotriosidase	125..491	CDD:119351	83/385 (22%)
		Glyco_18	559..898	CDD:214753
		GH18_chitolectin_chitotriosidase	560..919	CDD:119351
		CBM_14	951..1005	CDD:279884
chil-6	NP_496126.1	Glyco_18	113..431	CDD:214753	76/358 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810