DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cht7 and chil-13

DIOPT Version :9

Sequence 1:	NP_647768.3	Gene:	Cht7 / 38370	FlyBaseID:	FBgn0035398	Length:	1013	Species:	Drosophila melanogaster
Sequence 2:	NP_496018.2	Gene:	chil-13 / 174500	WormBaseID:	WBGene00010945	Length:	439	Species:	Caenorhabditis elegans

Alignment Length:	377	Identity:	92/377 - (24%)
Similarity:	173/377 - (45%)	Gaps:	55/377 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   549 NAVASNTRPAQVFCYLTSWSAKRPGAGKF--------QPENIDPKLCTHIVYAFATLQDYKLTEA 605
            |.|.:|..|.:..|       ||...|.|        ....|| || ||.|:||..:: |..|..
Worm    65 NLVLNNESPKKPVC-------KRRIVGYFSEIESTEISKSQID-KL-THAVFAFVRIK-YDGTLQ 119

  Fly   606 TDDDPENYE-SVIALRDNNPDLQILLAIGGWAFGSTPFKELTSNVFRMNQFVYEAIDFLRDYKFN 669
            .|:...:.. |::..:....:::::::|||....:..|....|:..:...|:...:.||.:::.:
Worm   120 FDNSKADLRFSILKDKTRGSNVEMMVSIGGGYENAHYFASALSDSQKKKNFIDSILAFLVEHRID 184

  Fly   670 GLDVDWEYPRGAEDRVAYVSLLKELRVAFEGEAKSSGLPRLLLTAAVPAS-FEAIAAGYDVPEIS 733
            |:|..|::|. .:|...||:.::|||...:...:.    ..|::..|||: .:....|:|:.|:.
Worm   185 GVDFFWQWPT-VQDTFNYVTFIRELRQKLDENKRK----HFLISMTVPAAGVDNWELGFDLEELQ 244

  Fly   734 KYLDFINVMTYDFHG----QWERTVGHNSPLFALESATGYQKKLTVDYSAREWVKQGAPKEKLLI 794
            .::||.||.:.|:.|    ||....|.:||:|   ...|.:|...||::.:.:..:......|.:
Worm   245 NHVDFFNVYSMDYAGPWPNQWGVPTGPSSPMF---YNIGARKNFYVDWTMKHYTCKLKQPSMLNM 306

  Fly   795 GMPTYGRSFELVN---DTQFDI-------GSPSSGGGKAGKFTNEAGFLSYYEVCSFLAADNTTL 849
            .:|...|.:..|.   |.:.::       .:.:.|..:..::|.|...|.       |:..:
Worm   307 VIPFSARIWNNVQEAIDNRTEVFRNAELKNNMAEGRTQISRWTAEHEGLE-------LSPSS--- 361

  Fly   850 VWDSEQQVPFA--YRGNQWVGFDDERSLKTKTEWLKEQGFGGIMVWSIDMDD 899
             ||:....|:.  .:...::.|:|:||:|.||::.|:...||:.:||:||||
Worm   362 -WDNLTMTPYILDLKAKTFLTFEDKRSIKIKTDYAKKMDLGGVWLWSVDMDD 412

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht7	NP_647768.3	Glyco_18	124..468	CDD:214753
		GH18_chitolectin_chitotriosidase	125..491	CDD:119351
		Glyco_18	559..898	CDD:214753	85/364 (23%)
		GH18_chitolectin_chitotriosidase	560..919	CDD:119351	88/366 (24%)
		CBM_14	951..1005	CDD:279884
chil-13	NP_496018.2	Glyco_18	81..411	CDD:214753	82/351 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264489at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm14141
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820