DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht7 and cht-2

DIOPT Version :9

Sequence 1:	NP_647768.3	Gene:	Cht7 / 38370	FlyBaseID:	FBgn0035398	Length:	1013	Species:	Drosophila melanogaster
Sequence 2:	NP_495798.2	Gene:	cht-2 / 174363	WormBaseID:	WBGene00011757	Length:	626	Species:	Caenorhabditis elegans

Alignment Length:	484	Identity:	135/484 - (27%)
Similarity:	213/484 - (44%)	Gaps:	96/484 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   563 YLTSWSAKRPGAGKFQPENIDPKLCTHIVYAFATL-QDYKLTEATDDDPENYESVIALRDNNPDL 626
            |:||| .|.|    |:.:..: || ||:|:||..: .|..:....|......|.|..:...:|||
Worm    37 YITSW-GKHP----FRDDQAE-KL-THLVFAFFVVDSDGSVKLEGDAAKARLEHVKEVASRHPDL 94

  Fly   627 QILLAIGGWAFGSTPFKELTSNVFRMNQFVYEAIDFLRDYKFNGLDVDWEYP--RGA-----EDR 684
            ::|.|:|||. .|..|..||::..|.:..:...:..:::|.|:|:|:|||||  .||     .||
Worm    95 KLLYAVGGWE-NSQYFSVLTADHSRRSILISNFVKVIKEYGFDGVDIDWEYPVTGGAVEGTPADR 158

  Fly   685 VAYVSLLKELRVAFEGEAKSSGLPRLLLTAAVPASFEAIAAGYDVPEISKYLDFINVMTYDFHG- 748
            ..||:|::|||.........:| ...|::.|..|....:..|||:.::.||.||:|||:||:.|
Worm   159 RNYVNLMRELRNELRDLESETG-KSYLISFAGAAGHWVLKPGYDLQQLMKYCDFVNVMSYDYFGA 222

  Fly   749 ---QWERTVGHNSPL-FALESATGYQKKLTVDYSAREWVKQGAPKEKLLIGMPTYGRSFELVN-- 807
               :|....|..:|| ||:...  :..::.|..:.:::..|....:|:.:|:|.|||.::.|.
Worm   223 WASKWGAYTGPPAPLQFAMPKK--FSGRMNVHATMKDYSCQIKATDKINMGVPFYGRFWKNVGDA 285

  Fly   808 -DTQFDIGSPSSGGGKAG-KFTNEAGFLSYYEV--------CSFLAADNTTLVWDSEQQVPFAYR 862
             |:..|:...::.....| ||  |.|.:.:.::        ..|.:...|..:|.|||:.
Worm   286 VDSTDDMWRTATATNSEGTKF--EGGDVQWRDLHEKFDTTKTKFHSGSKTPFIWLSEQKT----- 343

  Fly   863 GNQWVGFDDERSLKTKTEWLKEQGFGGIMVWSIDMDDFSGRCGSGKYPLLTALNDELKD------ 921
               :||:::..|||.|.:::.|...||:|:|:||.||..|          |.||....:
Worm   344 ---FVGYENAESLKHKVDYIVENNIGGVMIWAIDFDDDQG----------TLLNSAAAESICTTS 395

  Fly   922 -----YKVE-------LEYDGPYESHGP--------RGAYTTKDPHDVTCAEEDGHISYHKDWAD 966
                 ||..       ..||...|..|.        .|.|...||.|      .||       |.
Worm   396 TKSFNYKCSPVDDKRWWTYDDNEELAGMCGKSSPLIDGYYPVCDPDD------PGH-------AC 447

  Fly   967 CTHYYMCEGERKHHMPCPANLVFNPQENV 995
            |..|..| |.......||..:.:....|:
Worm   448 CGKYGYC-GSGAEFCSCPECIDYGADPNL 475

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht7	NP_647768.3	Glyco_18	124..468	CDD:214753
		GH18_chitolectin_chitotriosidase	125..491	CDD:119351
		Glyco_18	559..898	CDD:214753	108/359 (30%)
		GH18_chitolectin_chitotriosidase	560..919	CDD:119351	114/380 (30%)
		CBM_14	951..1005	CDD:279884	10/45 (22%)
cht-2	NP_495798.2	Glyco_18	33..376	CDD:214753	108/359 (30%)
		GH18_chitinase-like	35..376	CDD:299167	108/359 (30%)
		ChtBD1_GH18_2	418..469	CDD:211315	16/64 (25%)
		ChtBD1_GH18_2	496..547	CDD:211315
		ChtBD1_GH18_2	567..618	CDD:211315
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm14141
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X91
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.810