DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht7 and chil-24

DIOPT Version :9

Sequence 1:	NP_647768.3	Gene:	Cht7 / 38370	FlyBaseID:	FBgn0035398	Length:	1013	Species:	Drosophila melanogaster
Sequence 2:	NP_494455.1	Gene:	chil-24 / 173661	WormBaseID:	WBGene00020407	Length:	410	Species:	Caenorhabditis elegans

Alignment Length:	406	Identity:	101/406 - (24%)
Similarity:	188/406 - (46%)	Gaps:	71/406 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   109 SSLKGKKTKVDDGTPKIVCYYTNWSQYRV---KIGKFVPEDIPADLCTHIIFAFGWLKKNKLSSY 170
            |:.|....:.:....:||.:|.:|.:..:   ::.|.          ||.:||:..:|.:....:
Worm    40 SNYKMSNNETETTPSRIVGFYADWERTDITSHQVAKL----------THAVFAYVQMKFDGSLGF 94

  Fly   171 ESNDETKDNVPGLYERMMTLKKANPKLKILLALGGWSFGTQKFKDMSSTRYTRQTFVYSAIPFLR 235
            : ||..:.....|.:::...:.:|  :|:::::||:. .:|.|..:.|....::.|:.|...||.
Worm    95 K-NDAARIRFSNLRDKVRRNEDSN--VKMMISIGGFE-NSQHFYPVLSNVEMKKAFLNSISSFLA 155

  Fly   236 KRGFDGLDMDWEYPKGSDDKKNFVLLLKELREAFEAEAQELKKPRLLLSAAVPVGP-DNIRGGYD 299
            .....|:|:.|::| ..:||.::...|.:||:....|        .::|.|||... .|:..|||
Worm   156 YHELHGVDIFWKWP-SPEDKAHYSRFLADLRQHLGYE--------FIISVAVPQAEVSNLELGYD 211

  Fly   300 VPAIASYLDFINLMAYDFHGKWERE----TGHNAPLYAPSTDS-EWRKQLSVDNAASLWVKMGAP 359
            :..|:|::||.|:.:.|::|.|..|    ||..:|||.|:..: :|..:...:       |.|.|
Worm   212 LRTISSHVDFFNVHSMDYYGPWPNEWGKPTGPISPLYGPTRHNVDWTLRYYAE-------KTGEP 269

  Fly   360 KEKLVIGMPTYGRSFTLANPDKHGPNAPASGGGR-----EGVYTKEGG------FLAYYEICEML 413
             .||.:.:|.:.|.:      |:.|. |...|.:     |.|..|..|      :.|.:|  |:.
Worm   270 -GKLNMVIPFFVRLW------KNVPE-PVEPGRQVFRDVELVDNKPQGEAYMSRWSAQHE--ELD 324

  Fly   414 LNGAVYVWDDEMKVPYLVDGD--QWVGFDDERAIRNKMHWIKSNGFGGAMVWTIDMDD------- 469
            |:.|  .||:|.:..|..:.|  .:|.|:.:::|:.||.::|....||..:|.:|.::
Worm   325 LSPA--DWDEETRSSYTWNPDTRNFVTFETDKSIQEKMKYVKEKNLGGVWIWHVDANEKLLDSVR 387

  Fly   470 FKGEVCGGNVKYPLIG 485
            |.||....:.:|..||
Worm   388 FDGEGVVDDQEYREIG 403

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht7	NP_647768.3	Glyco_18	124..468	CDD:214753	93/365 (25%)
		GH18_chitolectin_chitotriosidase	125..491	CDD:119351	99/390 (25%)
		Glyco_18	559..898	CDD:214753
		GH18_chitolectin_chitotriosidase	560..919	CDD:119351
		CBM_14	951..1005	CDD:279884
chil-24	NP_494455.1	Glyco_18	55..378	CDD:214753	92/364 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm14141
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810