DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PAN3 and prkci

DIOPT Version :9

Sequence 1:	NP_647767.1	Gene:	PAN3 / 38369	FlyBaseID:	FBgn0035397	Length:	790	Species:	Drosophila melanogaster
Sequence 2:	NP_571930.2	Gene:	prkci / 117507	ZFINID:	ZDB-GENE-011105-1	Length:	588	Species:	Danio rerio

Alignment Length:	378	Identity:	70/378 - (18%)
Similarity:	130/378 - (34%)	Gaps:	150/378 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly   470 VYDYHPGSQTLLAKYFTPAPETNGYTDPFQGE------------------------ARPFSHKSN 510
            :|:.:..|: |:...|...||..|.  |..||                        |:.|:.:::
Zfish    85 LYELNKDSE-LIIHVFPCVPEKPGM--PCPGEDKSIYRRGARRWRKLYYATGHAFQAKRFNRRAH 146

  Fly   511 MQRTSNGPLLPEATIWSIIMQLTAGLKAIHHAGLACKVLDPTKI--IVT---GKRVRFSSCCISD 570
            ....::       .||.:..|   |.|.|:     ||:|...|.  :||   |::|      |.|
Zfish   147 CAICTD-------RIWGLGRQ---GYKCIN-----CKLLVHKKCHKLVTVECGRQV------IQD 190

  Fly   571 --ITQFDPNASNP------LALVNM-----HQQDDLTALGRLVLALACRCLQSVQRDNVQSSIDM 622
              |.:.||.:::|      |...|.     |:.::..|:|            |.:.....||:.:
Zfish   191 PMIGRIDPGSTHPEHPDQVLGKKNSTESINHEGEEHEAVG------------SRESGKAVSSLGL 243

  Fly   623 VTRNYSTDLRNFIVYLFTTNNRRSVTDLMPMIGARFYTQLDALQSKIDMQEDELAKEMENGRLYR 687
            :         :|              ||:.:||...|.::..::.|            :..|:|.
Zfish   244 I---------DF--------------DLLRVIGRGSYAKVLLVRLK------------KTERIYA 273

  Fly   688 I-LVKLNSINERPDFNLDCTWSETGDRYML--------------------KLF--------RDYL 723
            : :||...:|:..|.:    |.:| ::::.                    :||        .|.:
Zfish   274 MKVVKKELVNDDEDID----WVQT-EKHVFEQASNHPFLVGLHSCFQTESRLFFVIEYVNGGDLM 333

  Fly   724 FHSVTEDGRPWLDHAHIVQCLNKLDAGSIERVQLMSRDEQ--SVLIVSYAELK 774
            ||...:...| .:||........|....:....::.||.:  :||:.|...:|
Zfish   334 FHMQRQRKLP-EEHARFYSAEISLALNYLHERGIIYRDLKLDNVLLDSEGHIK 385

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PAN3	NP_647767.1	DUF4797	245..284	CDD:292670
PAN3	NP_647767.1	PKc	406..>570	CDD:270622	27/128 (21%)
prkci	NP_571930.2	PB1_aPKC	19..101	CDD:99725	4/16 (25%)
		C1_1	134..184	CDD:278556	14/64 (22%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	194..213		4/18 (22%)
		STKc_aPKC_iota	225..588	CDD:270769	35/214 (16%)
		S_TKc	246..514	CDD:214567	30/172 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910