DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32486 and TRAF4

DIOPT Version :9

Sequence 1:	NP_647765.1	Gene:	CG32486 / 38367	FlyBaseID:	FBgn0266918	Length:	412	Species:	Drosophila melanogaster
Sequence 2:	XP_011523806.1	Gene:	TRAF4 / 9618	HGNCID:	12034	Length:	477	Species:	Homo sapiens

Alignment Length:	182	Identity:	40/182 - (21%)
Similarity:	62/182 - (34%)	Gaps:	49/182 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    98 GMHEKLAHRISNALCCAVCLDLPKTAMYQCQMGHLMCAACFTHLLADGRLRDQIATCPNCRVEIS 162
            |...|...:....|.|.:|....:..:.....||..|..|....|::|     :..||..::.:.
Human     3 GFDYKFLEKPKRRLLCPLCGKPMREPVQVSTCGHRFCDTCLQEFLSEG-----VFKCPEDQLPLD 62

  Fly   163 KSTASR-------NLAVEKAASELP-----------------------SECQF----CNKEFPYK 193
            .:....       :..:|.....||                       :.|.|    |....|.|
Human    63 YAKFPHPYPQIYPDPELEVQVLGLPIRCIHSEEGCRWSGPLRHLQGHLNTCSFNVIPCPNRCPMK 127

  Fly   194 ----SLERHEQHECQERPTKCKYHRIGCQWRGPYHETNEHERNCLHPQKSGY 241
                .|..|.||:|.:|..||::  .||.:.|..:|:  ||..|  ||:|.|
Human   128 LSRRDLPAHLQHDCPKRRLKCEF--CGCDFSGEAYES--HEGMC--PQESVY 173

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32486	NP_647765.1	zf-C3HC4_3	109..164	CDD:290631	11/54 (20%)
CG32486	NP_647765.1	Sina	168..>232	CDD:302762	22/101 (22%)
TRAF4	XP_011523806.1	RING	18..55	CDD:238093	8/41 (20%)
		zf-TRAF	109..163	CDD:280357	17/57 (30%)
		zf-TRAF	217..276	CDD:280357
		MATH_TRAF4	315..470	CDD:239750
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	0	0.000