Protein Alignment CG32486 and SIAH2

DIOPT Version :9

• Sequence 1: NP_647765.1
• Gene: CG32486 / 38367
• FlyBaseID: FBgn0266918
• Length: 412
• Species: Drosophila melanogaster
• Sequence 2: NP_005058.3
• Gene: SIAH2 / 6478
• HGNCID: 10858
• Length: 324
• Species: Homo sapiens
• Alignment Length: 342
• Identity: 79/342 - (23%)
• Similarity: 127/342 - (37%)
• Gaps: 83/342 - (24%)

  Fly    11 QQPPSSSNLPLLGDNQAVATTSSASSASSSSTSSSSSSVGGGNVVGVPLDTQGSGEPPAKKQLLD 75
            |.||...:.|......|.||.|:|...||:..::::       |:..|
Human    18 QPPPQPQHTPSPAAPPAAATISAAGPGSSAVPAAAA-------VISGP----------------- 58

  Fly    76 GGGGGATSSSGSSLLSSAAAASGMHEKLAHRISNALCCAVCLDLPKTAMYQCQMGHLMCAACFTH 140
            |||||            |...|..|    |.:::...|.||.|.....:.|||.|||:|..|
Human    59 GGGGG------------AGPVSPQH----HELTSLFECPVCFDYVLPPILQCQAGHLVCNQC--- 104

  Fly   141 LLADGRLRDQIATCPNCRVEISKSTASRNLAVEKAASELPSECQF----CNKEFPYKSLERHEQH 201
                   |.:::.||.||..::.|.  ||||:||.||.:...|::    |:....:.....||.
Human   105 -------RQKLSCCPTCRGALTPSI--RNLAMEKVASAVLFPCKYATTGCSLTLHHTEKPEHED- 159

  Fly   202 ECQERPTKCKYHRIGCQWRGPYHETNEHERNCLHPQKSGYEVMAALEAHDDRIKEEKKMFNTLID 266
            .|:.||..|......|:|:|.......|   .:|..||    :..|:..|.............:|
Human   160 ICEYRPYSCPCPGASCKWQGSLEAVMSH---LMHAHKS----ITTLQGEDIVFLATDINLPGAVD 217

  Fly   267 LLSYEKIIFNDLQMKPYRTDEYV-HKLFYETARFSAFNQQ---WVVKARINNSQRDPHQSNERTI 327
            .:..:....:...:...:.::|. |:.|:.........:|   :..:..:|        .|.|.:
Human   218 WVMMQSCFGHHFMLVLEKQEKYEGHQQFFAIVLLIGTRKQAENFAYRLELN--------GNRRRL 274

  Fly   328 TYQLILKTKTSTPMSIH 344
            |::       :||.|||
Human   275 TWE-------ATPRSIH 284

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32486	NP_647765.1	zf-C3HC4_3	109..164	CDD:290631	17/54 (31%)
		Sina	168..>232	CDD:302762	20/67 (30%)
SIAH2	NP_005058.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..42		8/23 (35%)
		RING-HC_SIAH2	78..115	CDD:319666	15/46 (33%)
		Sina	122..318	CDD:397316	39/188 (21%)
		SBD. /evidence=ECO:0000250|UniProtKB:P61092	130..322		33/178 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3002
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810