Protein Alignment CG32486 and SIAH1

DIOPT Version :9

• Sequence 1: NP_647765.1
• Gene: CG32486 / 38367
• FlyBaseID: FBgn0266918
• Length: 412
• Species: Drosophila melanogaster
• Sequence 2: NP_001006611.1
• Gene: SIAH1 / 6477
• HGNCID: 10857
• Length: 313
• Species: Homo sapiens
• Alignment Length: 326
• Identity: 71/326 - (21%)
• Similarity: 113/326 - (34%)
• Gaps: 130/326 - (39%)

  Fly    59 LDTQGSGEPPAKK-QLLDGGGGGATSSSGSSLLSSAAAASGMHEKLAHRISNALCCAVCLDLPKT 122
            |.|..|..||::: ..|.|     |::|.:.|.|       :.|           |.||.|....
Human    40 LPTGTSKCPPSQRVPALTG-----TTASNNDLAS-------LFE-----------CPVCFDYVLP 81

  Fly   123 AMYQCQMGHLMCAACFTHLLADGRLRDQIATCPNCRVEISKSTASRNLAVEKAASELPSECQF-- 185
            .:.|||.|||:|:.|          |.::..||.||..:.   :.||||:||.|:.:...|::
Human    82 PILQCQSGHLVCSNC----------RPKLTCCPTCRGPLG---SIRNLAMEKVANSVLFPCKYAS 133

  Fly   186 --CNKEFPYKSLERHEQHECQERPTKCKYHRIGCQWRGPYHETNEHERNCLHPQKS--------- 239
              |....|:.....||: .|:.||..|......|:|:|.......|   .:|..||
Human   134 SGCEITLPHTEKADHEE-LCEFRPYSCPCPGASCKWQGSLDAVMPH---LMHQHKSITTLQGEDI 194

  Fly   240 ----------------------GYEVMAALEAHDDRIKEEK----KMFNTLIDLLSYEKIIFNDL 278
                                  |:..|..||      |:||    :.|..::.|:...|
Human   195 VFLATDINLPGAVDWVMMQSCFGFHFMLVLE------KQEKYDGHQQFFAIVQLIGTRK------ 247

  Fly   279 QMKPYRTDEYVHKLFYETARFSAFNQQWVVKARINNSQRDPHQSNERTITYQLILKTKTSTPMSI 343
                 :.:.:.::|                  .:|        .:.|.:|::       :||.||
Human   248 -----QAENFAYRL------------------ELN--------GHRRRLTWE-------ATPRSI 274

  Fly   344 H 344
            |
Human   275 H 275

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32486	NP_647765.1	zf-C3HC4_3	109..164	CDD:290631	17/54 (31%)
		Sina	168..>232	CDD:302762	20/67 (30%)
SIAH1	NP_001006611.1	RING-HC_SIAH1	70..109	CDD:319665	18/59 (31%)
		RING-HC finger (C3HC4-type)	72..106	CDD:319665	15/43 (35%)
		Sina	113..309	CDD:367355	42/217 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3002
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810