DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32486 and Cyhr1

DIOPT Version :9

Sequence 1:	NP_647765.1	Gene:	CG32486 / 38367	FlyBaseID:	FBgn0266918	Length:	412	Species:	Drosophila melanogaster
Sequence 2:	NP_001263250.1	Gene:	Cyhr1 / 54151	MGIID:	1859320	Length:	412	Species:	Mus musculus

Alignment Length:	286	Identity:	123/286 - (43%)
Similarity:	171/286 - (59%)	Gaps:	23/286 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 PLLGDNQAVATTSSASSASSSSTSSSSSSVGGGNVVGVPLDT---------QGSGEP--PAKKQL 73
            |..|...||.......:...::...:::::|.....|:|.:.         :.:|:|  |.||:|
Mouse    12 PAAGPAGAVPAGVGVGAGPGAAAGPAAAALGEAAGPGIPDEAALAGARQLQEAAGDPDAPPKKRL 76

  Fly    74 LDGGGGGATSSSGSSLLSSAAAASGMHEKLAHRISNALCCAVCLDLPKTAMYQCQMGHLMCAACF 138
                   ..:.:..:..::.||.||   ||..|:.:.|||.|||||||.::|||..||||||.||
Mouse    77 -------RAAEAAEAAAAAVAAGSG---KLEERLYSVLCCTVCLDLPKASVYQCTNGHLMCAGCF 131

  Fly   139 THLLADGRLRDQIATCPNCRVEISKSTASRNLAVEKAASELPSECQFCNKEFPYKSLERHEQHEC 203
            .|||||.||:::.|||||||.|||||...||||||||.|||||||.||.::||...||||::.||
Mouse   132 IHLLADARLKEEQATCPNCRCEISKSLCCRNLAVEKAVSELPSECGFCLRQFPRSLLERHQKEEC 196

  Fly   204 QERPTKCKYHRIGCQWRGPYHETNEHERNCLHPQKSGYEVMAALEAHDDRIKEEKKMFNTLIDLL 268
            |:|.|:|||.||||.|.||:||...||..|.||.|:|.|:|..|:..|...::|.:::|::..||
Mouse   197 QDRVTQCKYKRIGCPWHGPFHELTVHEAACAHPTKTGNELMEILDEMDQSHRKEMQLYNSIFSLL 261

  Fly   269 SYEKIIFNDLQMKPY--RTDEYVHKL 292
            |:|||.:......||  .|::..|.:
Mouse   262 SFEKIGYTVWVFGPYLWSTEQEEHSI 287

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32486	NP_647765.1	zf-C3HC4_3	109..164	CDD:290631	38/54 (70%)
CG32486	NP_647765.1	Sina	168..>232	CDD:302762	42/63 (67%)
Cyhr1	NP_001263250.1	Sina	161..>222	CDD:302762	40/60 (67%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167830644
Domainoid	1	1.000	269	1.000	Domainoid score	I1828
eggNOG	1	0.900	-	-		E1_KOG3002
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H32791
Inparanoid	1	1.050	332	1.000	Inparanoid score	I2410
Isobase	1	0.950	-	0	Normalized mean entropy	S5622
OMA	1	1.010	-	-		QHG48416
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0007898
OrthoInspector	1	1.000	-	-		oto93004
orthoMCL	1	0.900	-	-		OOG6_109690
Panther	1	1.100	-	-	LDO	PTHR23059
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4529
SonicParanoid	1	1.000	-	-		X1167
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	15.740