DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32486 and CG34375

DIOPT Version :9

Sequence 1:	NP_647765.1	Gene:	CG32486 / 38367	FlyBaseID:	FBgn0266918	Length:	412	Species:	Drosophila melanogaster
Sequence 2:	NP_001163693.1	Gene:	CG34375 / 42715	FlyBaseID:	FBgn0085404	Length:	568	Species:	Drosophila melanogaster

Alignment Length:	355	Identity:	77/355 - (21%)
Similarity:	119/355 - (33%)	Gaps:	115/355 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    91 SSAAAASGMHEK--------LAHRISNALCCAVCLDLPKTAMYQCQMGHLMCAACFTHLLADGRL 147
            :|.|...|::::        |.| ||..|.|.|||::.|...:||..||::|..|
  Fly   101 ASHAVQHGINQQSLQKFATCLQH-ISQLLECPVCLEVIKPPGWQCCNGHVLCNNC---------- 154

  Fly   148 RDQIATCPNCRVEISKSTASRNLAVEK----AASELPSECQFCNKEFPYKSLERHEQHECQERPT 208
            |.:...||.|||.:  ....|.|..:|    .|...|.:....||      :...:.|.......
  Fly   155 RSRSVKCPVCRVPL--GPRGRCLLSDKLFTLLAESFPCDGGKTNK------VAASQGHGKLSSVN 211

  Fly   209 KC--KYHRIGCQWRGPYHETNEHERNCLHPQKSGYEVMAALEA-------------------HDD 252
            ||  :||.   |.:....:|:..:..|      |.::...||.                   .:.
  Fly   212 KCTNEYHN---QPKMALAKTSSGKSKC------GKQISRQLETVLVDQSPREIRRKSQQGQEQEQ 267

  Fly   253 RIKEEKKMFNTLIDLLSYEKII-------FNDLQMKPYRTDEYVHKLFYETARFSAFNQQWV--- 307
            .::|......|||.:...|..:       .|::.:||..      ||..::.|.:..:|..:
  Fly   268 AVQEAVLPRCTLIKVQHQEAAVEHFSEEGHNNMLVKPKL------KLSKKSWRITGPDQDGLRCD 326

  Fly   308 VKARINN--SQRDPHQSNERTITYQLILKTKTSTPMSIHFFALKGPFSDMKVSTQIYKHEFTETS 370
            ..|.|||  ..::..|..||                                  |...|| ...|
  Fly   327 EVATINNGVQVQEQQQQQER----------------------------------QQLGHE-KSAS 356

  Fly   371 TESEYYVLPLPDGVG-GSGSSECNRMLANK 399
            :||||.....|.|.. .|.|.:..:.:|||
  Fly   357 SESEYQNYHCPTGKSCSSHSYQLGQPVANK 386

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32486	NP_647765.1	zf-C3HC4_3	109..164	CDD:290631	18/54 (33%)
CG32486	NP_647765.1	Sina	168..>232	CDD:302762	14/69 (20%)
CG34375	NP_001163693.1	PDZ	13..86	CDD:238080
CG34375	NP_001163693.1	RING	129..168	CDD:238093	17/48 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3002
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900