DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1271 and NHO1

DIOPT Version :9

Sequence 1:	NP_647763.1	Gene:	CG1271 / 38364	FlyBaseID:	FBgn0035392	Length:	556	Species:	Drosophila melanogaster
Sequence 2:	NP_178161.1	Gene:	NHO1 / 844385	AraportID:	AT1G80460	Length:	522	Species:	Arabidopsis thaliana

Alignment Length:	559	Identity:	156/559 - (27%)
Similarity:	254/559 - (45%)	Gaps:	69/559 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 AEESGPPDSPAFILALDVGTTCVRSFVLDEQCEVRGSAVDAVELLN--PQPGYFEIEPESLWRKI 83
            |:|:|      ||.::|.|||..|..:.|.  :.|..|...||...  |:.|:.|.:|..:...:
plant     2 AKENG------FIGSIDQGTTSTRFIIYDH--DARPVASHQVEFTQFYPEAGWVEHDPMEILESV 58

  Fly    84 VGVITQAVKNAQLTPPDI----TCLTISTQRCTFLTWDHRSGEYYHNFITWKDLRADELVDQWNA 144
            ...|.:|:..|.....::    ..:.::.||.|.:.|...:|...|..|.|.|.|...:..:...
plant    59 KVCIAKALDKATADGHNVDGGLKAIGLTDQRETTVVWSKSTGLPLHKAIVWMDARTSSICRRLEK 123

  Fly   145 SWTKSSMNWFSYALFLLTRQSRFLAGSVLQLMNGQVTPRLLFEIMNNKKLKQALMQKKARVELLD 209
            .              |...:|.|:....|.:.......:||:.:.|...:|.|:.:..|....:|
plant   124 E--------------LSGGRSHFVESCGLPISTYFSAMKLLWLMENVDDVKDAIKKGDAIFGTID 174

  Fly   210 SWILHKLRTGSSRDKDVEHITDVTSSTATGLYDPFTLSWSPLISWLFGINSKILPRVVDNG---- 270
            :|::..:..|.:...   |:||||:::.|.|.:..||||........||.::|||::|.|.
plant   175 TWLIWNMTGGINGGL---HVTDVTNASRTMLMNLKTLSWDQDTLKTLGIPAEILPKIVSNSEVIG 236

  Fly   271 --YKGFGHVHPTAFGPDWANTEIPIAASLSDQTAAIWGSQCFQKNDVKVTMGTGAFLNLVTGDRC 333
              .||            |....|.||..|.||.||:.|..| :|.:.|.|.|||||:.|.||:
plant   237 EICKG------------WPIPGIKIAGCLGDQHAAMLGQAC-RKGEAKSTYGTGAFILLNTGE-- 286

  Fly   334 QAVISGMYPLVAWQFKKPTRQQGAVYCIEGASHDFGTVVTWAQ-SCELFDSPANTSDIAQSVPDT 397
            ..:.||...|....:|...:.| ..|.:||:....|..|.|.: |..:..|.:...|:|..|..|
plant   287 VPIKSGHGLLTTLAYKLGPQAQ-TNYALEGSIAIAGAAVQWLRDSLGIIKSASEIEDLAAMVDST 350

  Fly   398 NDVFFMPAFSGLGPP--VNDYRSASGFIGLTPSTTKAHMVRALLESIVFRLVQLIEAAEKETSQK 460
            ..|:|:|||:||..|  ..|.|...  ||:|..|.|:|:.||:|||:.|::..::::..|:..:|
plant   351 GGVYFVPAFNGLFAPWWREDARGVC--IGITRFTNKSHIARAVLESMCFQVKDVLDSMNKDAGEK 413

  Fly   461 --------LHMIRVDGGVSRNDFVCQFLADLSRLRVERADNAESSIMGATFMAGINLGIWR--DV 515
                    ..::|||||.:.|:.:.|..|||....|.|..:.|::.:||.:.||:.:|.|:  |:
plant   414 GSLNNGKGEFLLRVDGGATANNLLMQIQADLMGSPVVRPVDIETTALGAAYAAGLAVGFWKEADI 478

  Fly   516 NDLKRFRKVARVFEPRPKEYETIANRMDKWSRTIARFSD 554
            .:.....|.::||.|..:| .....::..|.:.:.|..|
plant   479 FESGEKAKNSKVFRPAMEE-GIRKKKVASWCKAVERTFD 516

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1271	NP_647763.1	GlpK	32..555	CDD:223628	153/548 (28%)
CG1271	NP_647763.1	FGGY_GK5_metazoa	32..552	CDD:212665	151/544 (28%)
NHO1	NP_178161.1	PLN02295	7..522	CDD:215166	153/548 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0554
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D519426at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10196
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	5	4.880