DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1271 and Katnal2

DIOPT Version :9

Sequence 1:	NP_647763.1	Gene:	CG1271 / 38364	FlyBaseID:	FBgn0035392	Length:	556	Species:	Drosophila melanogaster
Sequence 2:	NP_001355584.1	Gene:	Katnal2 / 71206	MGIID:	1924234	Length:	539	Species:	Mus musculus

Alignment Length:	182	Identity:	38/182 - (20%)
Similarity:	63/182 - (34%)	Gaps:	58/182 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 PSKVAAKPAGAAKDS------QCAEESGPPDSPAFILALDVGTT--------CVRSFVLDEQCEV 54
            ||:...|......||      .|.::|.|..|     |:..|.|        .|:..|.|.|.|.
Mouse   102 PSRSGGKNKRLTNDSCQNLPKICHQKSRPKTS-----AVKTGDTKSVKEHLKQVKESVTDTQAES 161

  Fly    55 RGSAVDAVELLNPQPGYFEIEPESLWRKIV---GVITQAVKNAQLTPPDITCLTISTQRC----- 111
            ....::..::...||   |.:.:....:|:   |:::.|:|.|      .:...::|..|
Mouse   162 TDFGLNISKIHKDQP---EEKAQPRRGQIIDFRGLLSDAIKGA------TSEFALNTFECNPDPS 217

  Fly   112 --------TFLTWDHRSGE---------YYHN-FITWKDL----RADELVDQ 141
                    .|:..:....|         |.|| .|.|.|:    .|.:||.:
Mouse   218 ERLLKPLSAFIGMNSEMRELAAVVSRDIYLHNPNIKWNDIIGLDAAKQLVKE 269

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1271	NP_647763.1	GlpK	32..555	CDD:223628	29/148 (20%)
CG1271	NP_647763.1	FGGY_GK5_metazoa	32..552	CDD:212665	29/148 (20%)
Katnal2	NP_001355584.1	LisH	25..55	CDD:128913
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	93..121		5/18 (28%)
		SpoVK	<239..523	CDD:223540	9/31 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0554
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900