DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1271 and katnal2

DIOPT Version :9

Sequence 1:	NP_647763.1	Gene:	CG1271 / 38364	FlyBaseID:	FBgn0035392	Length:	556	Species:	Drosophila melanogaster
Sequence 2:	NP_001032491.1	Gene:	katnal2 / 641431	ZFINID:	ZDB-GENE-051113-156	Length:	485	Species:	Danio rerio

Alignment Length:	379	Identity:	74/379 - (19%)
Similarity:	128/379 - (33%)	Gaps:	127/379 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   186 FEIMNNKKLKQALMQ------------KKARVELLDSWILHKLRTGSSRDKDVEHITDV------ 232
            ||:.:|..|:..||:            .|...:|.:.....::::...|...:..|..:
Zfish    60 FEVCDNVDLETVLMEYESYYFIKFQKYPKLTKKLAEQGESRRIKSCGKRSHTLPRINSIQRPSSR 124

  Fly   233 -----TSSTATG-----------LYDPFTLSWSPLISWLFGIN-SKILPRVVDNG-------YKG 273
                 :.|..||           |....||.        ||:| |.|:....:.|       |:.
Zfish   125 NTVKKSESKLTGRDFSKSSDGDRLTSADTLG--------FGLNVSPIIRNGAEEGTHMRKIDYRN 181

  Fly   274 F------GHVHPTAFGPDWANTEIPIAASLSDQTAAIWGSQCFQKNDVKVTMGTGAFLNLVTGDR 332
            .      |..:.|....|:...|     .|....:|:.|    ..:|:|               .
Zfish   182 LIQDAVRGAANDTLHNADFTEQE-----RLLKPVSALIG----MNSDMK---------------E 222

  Fly   333 CQAVIS-GMY---PLVAW------QFKKPTRQQGAVYCIEGASHDFGTVVTWAQSCELFDSP-AN 386
            ..|||| .:|   |.|.|      :..|...::..||.|:......|.:..| :...|:..| ..
Zfish   223 LAAVISRDIYLHNPNVRWDDIIGLEAAKRLVKEAVVYPIKYPQLFTGILSPW-KGLLLYGPPGTG 286

  Fly   387 TSDIAQSV-PDTNDVFFMPAFSGLGPPVNDYRSASGFIGLTPSTTKAHMVRALLE-------SIV 443
            .:.:|::| .:.|..||..:.|.:   |:.:|..|           ..:||.|.|       |.:
Zfish   287 KTMLAKAVATECNTTFFNISASSI---VSKWRGDS-----------EKLVRVLFELARYHAPSTI 337

  Fly   444 F--RLVQLI------EAAEKETSQKLH---MIRVDGGVSRNDFVCQFLADLSRL 486
            |  .|..::      :..:.|.|:::.   ::::||....||.|  |:...|.|
Zfish   338 FLDELESVMSQRGVGQGGDHEGSRRMKTELLVQMDGLARSNDLV--FVLAASNL 389

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1271	NP_647763.1	GlpK	32..555	CDD:223628	74/379 (20%)
CG1271	NP_647763.1	FGGY_GK5_metazoa	32..552	CDD:212665	74/379 (20%)
katnal2	NP_001032491.1	LisH	25..55	CDD:128913
		P-loop_NTPase	242..>296	CDD:304359	10/54 (19%)
		AAA	273..410	CDD:214640	29/134 (22%)
		AAA	277..409	CDD:278434	28/129 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0554
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900